Search Results - "THALER, HOWARD T."

Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment by Simões, Rui V, Serganova, Inna S, Kruchevsky, Natalia, Leftin, Avigdor, Shestov, Alexander A, Thaler, Howard T, Sukenick, George, Locasale, Jason W, Blasberg, Ronald G, Koutcher, Jason A, Ackerstaff, Ellen

“…Abstract Cancer cells adapt their metabolism during tumorigenesis. We studied two isogenic breast cancer cells lines (highly metastatic 4T1; nonmetastatic…”
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Trastuzumab interruption and treatment-induced cardiotoxicity in early HER2-positive breast cancer by Yu, Anthony F., Yadav, Nandini U., Lung, Betty Y., Eaton, Anne A., Thaler, Howard T., Hudis, Clifford A., Dang, Chau T., Steingart, Richard M.

“…Trastuzumab improves outcomes among patients with HER2-positive breast cancer but is associated with a risk of treatment-induced cardiotoxicity (TIC). It is…”
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Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas by Zang, Xingxing, Sullivan, Peggy S, Soslow, Robert A, Waitz, Rebecca, Reuter, Victor E, Wilton, Andrew, Thaler, Howard T, Arul, Manonmani, Slovin, Susan F, Wei, Joyce, Spriggs, David R, Dupont, Jakob, Allison, James P

“…B7-H3 and B7x are members of the B7 family of immune regulatory ligands that are thought to attenuate peripheral immune responses through co-inhibition…”
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Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Predictor of Outcome in Head-and-Neck Squamous Cell Carcinoma Patients With Nodal Metastases by Shukla-Dave, Amita, Ph.D, Lee, Nancy Y., M.D, Jansen, Jacobus F.A., Ph.D, Thaler, Howard T., Ph.D, Stambuk, Hilda E., M.D, Fury, Matthew G., M.D, Patel, Snehal G., M.D, Moreira, Andre L., M.D, Sherman, Eric, M.D, Karimi, Sasan, M.D, Wang, Ya, M.S, Kraus, Dennis, M.D, Shah, Jatin P., M.D, Pfister, David G., M.D, Koutcher, Jason A., M.D., Ph.D

“…Purpose Dynamic contrast-enhanced MRI (DCE-MRI) can provide information regarding tumor perfusion and permeability and has shown prognostic value in certain…”
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Phase III Study of Cisplatin With or Without Paclitaxel in Stage IVB, Recurrent, or Persistent Squamous Cell Carcinoma of the Cervix: A Gynecologic Oncology Group Study by MOORE, David H, BLESSING, John A, ROCERETO, Thomas F, MCQUELLON, Richard P, THALER, Howard T, CELLA, David, BENDA, Jo, MILLER, David S, OLT, George, KING, Stephanie, BOGGESS, John F

“…To determine whether cisplatin plus paclitaxel (C+P) improved response rate, progression-free survival (PFS), or survival compared with cisplatin alone in…”
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Brain natriuretic peptide and risk of atrial fibrillation after thoracic surgery by Amar, David, MD, Zhang, Hao, MD, Shi, Weiji, MS, Downey, Robert J., MD, Bains, Manjit S., MD, Park, Bernard J., MD, Flores, Raja, MD, Rizk, Nabil, MD, Thaler, Howard T., PhD, Rusch, Valerie W., MD

“…Objectives Postoperative atrial fibrillation (POAF) complicating general thoracic surgery is a marker of increased morbidity and stroke risk. Our goal was to…”
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Cost-Effectiveness Analysis of Robotically Assisted Laparoscopy for Newly Diagnosed Uterine Cancers by Leitao, Mario M., Bartashnik, Aleksandra, Wagner, Isaac, Lee, Stephen J., Caroline, Ari, Hoskins, William J., Thaler, Howard T., Abu-Rustum, Nadeem R., Sonoda, Yukio, Brown, Carol L., Jewell, Elizabeth L., Barakat, Richard R., Gardner, Ginger J.

“…To assess the direct costs of three surgical approaches in uterine cancer and the cost-effectiveness of incorporating robot-assisted surgery. A cost system…”
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Preoperative left atrial dysfunction and risk of postoperative atrial fibrillation complicating thoracic surgery by Raman, Tina, MA, Roistacher, Nancy, MD, Liu, Jennifer, MD, Zhang, Hao, MD, Shi, Weiji, MS, Thaler, Howard T., PhD, Amar, David, MD

“…Objective Postoperative atrial fibrillation complicating general thoracic surgery increases morbidity and stroke risk. We aimed to determine whether…”
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Methadone Use and the Risk of Hypoglycemia for Inpatients With Cancer Pain by Flory, James H., MD, MSCE, Wiesenthal, Alison C., MD, Thaler, Howard T., PhD, Koranteng, Lauren, PharmD, Moryl, Natalie, MD

“…Abstract Context Methadone is an important drug in the management of both cancer-related and non–cancer-related pain and is the main pharmacologic agent used…”
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Statin use is associated with a reduction in atrial fibrillation after noncardiac thoracic surgery independent of C-reactive protein by Amar, David, Zhang, Hao, Heerdt, Paul M, Park, Bernard, Fleisher, Martin, Thaler, Howard T

“…The level of C-reactive protein (CRP) has been shown to be elevated in patients with atrial fibrillation/flutter (AF) unrelated to surgery, and statins are…”
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A Clinical Prediction Rule for Pulmonary Complications After Thoracic Surgery for Primary Lung Cancer by Amar, David, Munoz, Daisy, Shi, Weiji, Zhang, Hao, Thaler, Howard T.

“…There is controversy surrounding the value of the predicted postoperative diffusing capacity of lung for carbon monoxide (DLCOppo) in comparison to the forced…”
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Quality of Life and Symptom Control after Stent Placement or Surgical Palliation of Malignant Colorectal Obstruction by Nagula, Satish, MD, Ishill, Nicole, MS, Nash, Carla, MD, Markowitz, Arnold J., MD, Schattner, Mark A., MD, Temple, Larissa, MD, FACS, Weiser, Martin R., MD, FACS, Thaler, Howard T., PhD, Zauber, Ann, PhD, Gerdes, Hans, MD

“…Background Emergent surgical management of malignant large bowel obstruction (LBO) carries a high rate of morbidity and mortality. Self-expanding metal stents…”
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Beneficial effects of perioperative statins for major pulmonary resection by Amar, David, MD, Park, Bernard, MD, Zhang, Hao, MD, Shi, Weiji, MS, Fleisher, Martin, PhD, Thaler, Howard T., PhD, Rusch, Valerie W., MD

“…Objectives Statins improve overall outcomes after noncardiac surgery. The primary aim of the study was to determine whether use of perioperative atorvastatin…”
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Celecoxib Inhibits Prostate Cancer Growth: Evidence of a Cyclooxygenase-2-Independent Mechanism by Patel, Manish I, Subbaramaiah, Kotha, Du, Baoheng, Chang, Mindy, Yang, Peiying, Newman, Robert A, Cordon-Cardo, Carlos, Thaler, Howard T, Dannenberg, Andrew J

“…Purpose: Selective cyclooxygenase-2 (COX-2) inhibitors may suppress carcinogenesis by both COX-2-dependent and COX-2-independent mechanisms. The primary…”
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The development of a validated instrument to evaluate bowel function after sphincter-preserving surgery for rectal cancer by TEMPLE, Larissa K, BACIK, Jennifer, SCHRAG, Deborah, WONG, W. Douglas, SAVATTA, Salvatore G, GOTTESMAN, Lester, PATY, Philip B, WEISER, Martin R, GUILLEM, José G, MINSKY, Bruce D, KALMAN, Michelle, THALER, Howard T

“…Sphincter-preserving surgery is technically feasible for many rectal cancers, but functional results are not well understood. Therefore, the purpose of this…”
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A quantitative measurement of the human somatic mutation rate by ARATEN, David J, GOLDE, David W, ZHANG, Rong H, THALER, Howard T, GARGIULO, Lucia, NOTARO, Rosario, LUZZATTO, Lucio

“…The mutation rate (mu) is a key biological feature of somatic cells that determines risk for malignant transformation, and it has been exceedingly difficult to…”
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Clinical prediction rule for atrial fibrillation after coronary artery bypass grafting by Amar, David, Shi, Weiji, Hogue, Charles W., Zhang, Hao, Passman, Rod S., Thomas, Betsy, Bach, Peter B., Damiano, Ralph, Thaler, Howard T.

“…This study was designed to devise and validate a practical prediction rule for atrial fibrillation/atrial flutter (AF) after coronary artery bypass grafting…”
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Imaging of HSV-tk Reporter Gene Expression: Comparison Between [18F]FEAU, [18F]FFEAU, and Other Imaging Probes by Miyagawa, Tadashi, Gogiberidze, George, Serganova, Inna, Cai, Shangde, Balatoni, Julius A, Thaler, Howard T, Ageyeva, Lyudmila, Pillarsetty, Nagavarakishore, Finn, Ronald D, Blasberg, Ronald G

“…Herpes virus type 1 thymidine kinase (HSV1-tk) and the mutant HSV1-sr39tk are the 2 most widely used "reporter genes" for radiotracer-based imaging. Two…”
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Early Detection and Prognosis of Ovarian Cancer Using Serum YKL-40 by DUPONT, Jakob, TANWAR, Meena K, SPRIGGS, David R, THALER, Howard T, FLEISHER, Martin, KAUFF, Noah, HENSLEY, Martee L, SABBATINI, Paul, ANDERSON, Sibyl, AGHAJANIAN, Carol, HOLLAND, Eric C

“…YKL-40 is a secreted glycoprotein (chitinase family). We compared YKL-40 with two ovarian cancer serum markers, CA125 and CA15-3, for the detection of…”
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Imaging the Norepinephrine Transporter in Neuroblastoma: A Comparison of [18F]-MFBG and 123I-MIBG by HANWEN ZHANG, RUIMIN HUANG, CHEUNG, Nai-Kong V, HONGFEN GUO, ZANZONICO, Pat B, THALER, Howard T, LEWIS, Jason S, BLASBERG, Ronald G

“…The norepinephrine transporter (NET) is a critical regulator of catecholamine uptake in normal physiology and is expressed in neuroendocrine tumors like…”
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