Search Results - "THAKKAR, P"

Epidemiologic and molecular prognostic review of glioblastoma by Thakkar, Jigisha P, Dolecek, Therese A, Horbinski, Craig, Ostrom, Quinn T, Lightner, Donita D, Barnholtz-Sloan, Jill S, Villano, John L

“…Glioblastoma multiforme (GBM) is the most common and aggressive primary central nervous system malignancy with a median survival of 15 months. The average…”
Get full text

Dynamical system analysis in teleparallel gravity with boundary term by Kadam, S. A., Thakkar, Ninaad P., Mishra, B.

“…In this paper, we perform the dynamical system analysis of the cosmological models framed in the extended teleparallel gravity, the f ( T ,  B ) gravity. We…”
Get full text

Niosomes: Novel sustained release nonionic stable vesicular systems — An overview by Mahale, N.B., Thakkar, P.D., Mali, R.G., Walunj, D.R., Chaudhari, S.R.

“…Vesicular systems are novel means of delivering drug in controlled manner to enhance bioavailability and get therapeutic effect over a longer period of time…”
Get full text

Epidemiology of meningiomas post‐Public Law 107‐206: The Benign Brain Tumor Cancer Registries Amendment Act by Dolecek, Therese A., Dressler, Emily Van Meter, Thakkar, Jigisha P., Liu, Meng, Al‐Qaisi, Abeer, Villano, John L.

“…BACKGROUND The current analysis follows the implementation of Public Law 107‐260, the Benign Brain Tumor Cancer Registries Amendment Act, which mandated the…”
Get full text

A Review of an Unfavorable Subset of Breast Cancer: Estrogen Receptor Positive Progesterone Receptor Negative by Thakkar, Jigisha P., Mehta, Divyesh G.

“…Estrogen receptor (ER)+ progesterone receptor (PR)− tumors are a distinct subset of breast cancers characterized by aggressive behavior and tamoxifen…”
Get full text

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability by Reddy, Kaalak, Schmidt, Monika H M, Geist, Jaimie M, Thakkar, Neha P, Panigrahi, Gagan B, Wang, Yuh-Hwa, Pearson, Christopher E

“…R-loops, transcriptionally-induced RNA:DNA hybrids, occurring at repeat tracts (CTG)n, (CAG)n, (CGG)n, (CCG)n and (GAA)n, are associated with diseases…”
Get full text

Ethosomal Hydrogel of Raloxifene HCl: Statistical Optimization & Ex Vivo Permeability Evaluation Across Microporated Pig Ear Skin by Thakkar, Hetal P, Savsani, Hitesh, Kumar, Praveen

“…The oral bioavailability of Raloxifene hydrochloride, an FDA approved selective estrogen receptor modulator, is severely limited due to its poor aqueous…”
Get more information

Primary CNS germ cell tumors: current epidemiology and update on treatment by Thakkar, Jigisha P., Chew, Lita, Villano, J. Lee

“…Primary central nervous system (CNS) germ cell tumors (GCTs) are a heterogeneous group of lesions that account for 0.5 % of all primary brain and CNS tumors,…”
Get full text

Age-Specific Cancer Incidence Rates Increase Through the Oldest Age Groups by Thakkar, Jigisha P., MBBS, Villano, John L., MD, PhD, McCarthy, Bridget J., PhD

“…Abstract Background In the United States, from 2005 to 2009, nearly 8% of all cancers diagnosed and 15% of cancer deaths occurred in individuals aged 85 years…”
Get full text

Histomorphological Spectrum and Immunohistochemical Features of Gastrointestinal Stromal Tumour: A Series of Eight Cases by Babaria, Sneha Samir, Dayal, Anupama, Thakkar, Himali P, Joshi, Deepak S

“…Gastrointestinal Stromal Tumours (GISTs) are rare tumours of the Gastrointestinal Tract (GIT), consisting of <1% of all primary GIT neoplasms. Recent studies…”
Get full text

To evaluate and compare the efficacy of combined sucrose and non-nutritive sucking for analgesia in newborns undergoing minor painful procedure: a randomized controlled trial by Thakkar, P, Arora, K, Goyal, K, Das, R R, Javadekar, B, Aiyer, S, Panigrahi, S K

“…Objective: The objective of this study was to evaluate and compare the efficacy of combined sucrose and non-nutritive sucking (NNS) for analgesia in newborn…”
Get full text

Pharmacological interventions for drug-using offenders: an update to a systematic review and meta-analysis by Glanville, J. M., Perry, A. E., James, M. Martyn-St, Hewitt, C., Swami, S., Wright, K., Burns, L., Pearson, C., Aboaja, A., Thakkar, P., Kumar, K. M. S., Bunney, M.

“…This updated systematic review assesses the effects of pharmacological interventions for drug-using offenders. Methods Systematic review protocols and…”
Get full text

Development and Evaluation of a Once-Daily Controlled Porosity Osmotic Pump of Tapentadol Hydrochloride by Thakkar, Hetal P., Pancholi, Nirav, Patel, Chintankumar V.

“…The present study aimed to prepare, optimize, and evaluate Tapentadol hydrochloride controlled porosity osmotic pump (CPOP) and to achieve the drug release at…”
Get full text

Efficacy and safety over 26 weeks of an oral treatment strategy including sitagliptin compared with an injectable treatment strategy with liraglutide in patients with type 2 diabetes mellitus inadequately controlled on metformin: a randomised clinical trial by Charbonnel, B., Steinberg, H., Eymard, E., Xu, L., Thakkar, P., Prabhu, V., Davies, M. J., Engel, S. S.

“…Aims/hypothesis The aim of this work was to compare treatment intensification strategies based on orally administered vs injectable incretin-based…”
Get full text

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers by Shlien, Adam, Campbell, Brittany B, de Borja, Richard, Alexandrov, Ludmil B, Merico, Daniele, Wedge, David, Van Loo, Peter, Tarpey, Patrick S, Coupland, Paul, Behjati, Sam, Pollett, Aaron, Lipman, Tatiana, Heidari, Abolfazl, Deshmukh, Shriya, Avitzur, Na'ama, Meier, Bettina, Gerstung, Moritz, Hong, Ye, Merino, Diana M, Ramakrishna, Manasa, Remke, Marc, Arnold, Roland, Panigrahi, Gagan B, Thakkar, Neha P, Hodel, Karl P, Henninger, Erin E, Göksenin, A Yasemin, Bakry, Doua, Charames, George S, Druker, Harriet, Lerner-Ellis, Jordan, Mistry, Matthew, Dvir, Rina, Grant, Ronald, Elhasid, Ronit, Farah, Roula, Taylor, Glenn P, Nathan, Paul C, Alexander, Sarah, Ben-Shachar, Shay, Ling, Simon C, Gallinger, Steven, Constantini, Shlomi, Dirks, Peter, Huang, Annie, Scherer, Stephen W, Grundy, Richard G, Durno, Carol, Aronson, Melyssa, Gartner, Anton, Meyn, M Stephen, Taylor, Michael D, Pursell, Zachary F, Pearson, Christopher E, Malkin, David, Futreal, P Andrew, Stratton, Michael R, Bouffet, Eric, Hawkins, Cynthia, Campbell, Peter J, Tabori, Uri

“…Adam Shlien, Peter Campbell, Uri Tabori and colleagues report genome and exome sequencing of biallelic mismatch repair deficiency cancer samples from 12…”
Get full text

National cancer database analysis of outcomes in pediatric glioblastoma by Liu, Meng, Thakkar, Jigisha P., Garcia, Catherine R., Dolecek, Therese A., Wagner, Lars M., Dressler, Emily Van Meter, Villano, John L.

“…Glioblastoma in children is an aggressive disease with no defined standard therapy. We evaluated hospital‐based demographic and survival patterns obtained…”
Get full text

Statistically optimized fast dissolving microneedle transdermal patch of meloxicam: A patient friendly approach to manage arthritis by Amodwala, Sejal, Kumar, Praveen, Thakkar, Hetal P.

“…The long term administration of Meloxicam for the management of arthritis, a chronic disorder, results in gastrointestinal disturbances leading to poor patient…”
Get full text

Drug susceptibility testing of Mycobacterium tuberculosis against second-line drugs using the Bactec MGIT 960 System by RODRIGUES, C, JANI, J, SHENAI, S, THAKKAR, P, SIDDIQI, S, MEHTA, A

“…OBJECTIVE: To establish the critical test concentrations for seven second-line anti-tuberculosis drugs in the Bactec Mycobacterial Growth Indicator Tube (MGIT)…”
Get full text

Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma by Rabin, Erik E., Huang, Jonathan, Kim, Miri, Mozny, Andreas, Lauing, Kristen L., Penco-Campillo, Manon, Zhai, Lijie, Bommi, Prashant, Mi, Xinlei, Power, Erica A., Prabhu, Vikram C., Anderson, Douglas E., Barton, Kevin P., Walunas, Theresa L., Schiltz, Gary E., Amidei, Christina, Sanchez-Gomez, Pilar, Thakkar, Jigisha P., Lukas, Rimas V., Wainwright, Derek A.

“…Increased age is a strong and unfavorable prognostic factor for patients with glioblastoma (GBM). However, the relationships between stratified patient age,…”
Get full text

Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and pioglitazone on glycemic control and measures of β-cell function in patients with type 2 diabetes by Yoon, K H, Shockey, G R, Teng, R, Golm, G T, Thakkar, P R, Meehan, A G, Williams-Herman, D E, Kaufman, K D, Amatruda, J M, Steinberg, H

“…To assess the safety and efficacy of initial combination therapy with sitagliptin and pioglitazone compared with pioglitazone monotherapy in drug-naïve…”
Get more information