Search Results - "TETTAMANTI, Guido"
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Activation of the hypoxia-inducible factor 1α promotes myogenesis through the noncanonical Wnt pathway, leading to hypertrophic myotubes
Published in The FASEB journal (01-05-2017)“…Regeneration of skeletal muscle is a complex process that requires the activation of quiescent adult stem cells, called satellite cells, which are resident in…”
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Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes
Published in Nutrients (20-05-2017)“…Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs…”
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Activation of the hypoxia‐inducible factor 1a promotes myogenesis through the noncanonical Wnt pathway, leading to hypertrophic myotubes
Published in The FASEB journal (01-05-2017)“…ABSTRACT Regeneration of skeletal muscle is a complex process that requires the activation of quiescent adult stem cells, called satellite cells, which are…”
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The Plasma Membrane Sialidase NEU3 Regulates the Malignancy of Renal Carcinoma Cells by Controlling β1 Integrin Internalization and Recycling
Published in The Journal of biological chemistry (14-12-2012)“…The human plasma membrane sialidase NEU3 is a key enzyme in the catabolism of membrane gangliosides, is crucial in the regulation of cell surface processes,…”
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Dynamic and Structural Properties of Sphingolipids as Driving Forces for the Formation of Membrane Domains
Published in Chemical reviews (01-06-2006)“…This review focuses on some features of membrance sphingolipids that should be involved in the generation of lipid domains. It aims to show that extensive…”
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NEU3 Sialidase Protein Interactors in the Plasma Membrane and in the Endosomes
Published in The Journal of biological chemistry (13-05-2016)“…NEU3 sialidase has been shown to be a key player in many physio- and pathological processes, including cell differentiation, cellular response to hypoxic…”
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Isolation and Characterization of 2 New Human Rotator Cuff and Long Head of Biceps Tendon Cells Possessing Stem Cell–Like Self-Renewal and Multipotential Differentiation Capacity
Published in The American journal of sports medicine (01-07-2013)“…Background: Stem cell therapy is expected to offer new alternatives to the traditional therapies of rotator cuff tendon tears. In particular, resident,…”
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Casein phosphopeptides modulate calcium uptake and apoptosis in Caco2 cells through their interaction with the TRPV6 calcium channel
Published in Journal of functional foods (01-04-2013)“…Dietary calcium intake is associated with colon cancer incidence due to its ability to modulate proliferation and apoptosis, cellular function directly linked…”
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Gangliosides as a potential new class of stem cell markers: the case of GD1a in human bone marrow mesenchymal stem cells[S]
Published in Journal of lipid research (01-03-2014)“…Owing to their exposure on the cell surface and the possibility of being directly recognized with specific antibodies, glycosphingolipids have aroused great…”
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10
Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles
Published in BMC cancer (01-08-2014)“…In addition to alterations concerning the expression of oncogenes and onco-suppressors, melanoma is characterized by the presence of distinctive gangliosides…”
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Lipogems Product Treatment Increases the Proliferation Rate of Human Tendon Stem Cells without Affecting Their Stemness and Differentiation Capability
Published in Stem cells international (01-01-2016)“…Increasing the success rate of rotator cuff healing remains tremendous challenge. Among many approaches, the possibility of activating resident stem cells in…”
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Caseinphosphopeptide-induced calcium uptake in human intestinal cell lines HT-29 and Caco2 is correlated to cellular differentiation
Published in The Journal of nutritional biochemistry (01-03-2010)“…Caseinphosphopeptides (CPPs) are considered as mineral carriers because of their ability to bind and solubilize calcium ions, with the possible role, yet to be…”
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MmNEU3 sialidase over-expression in C2C12 myoblasts delays differentiation and induces hypertrophic myotube formation
Published in Journal of cellular biochemistry (01-09-2012)“…Several factors affect the skeletal muscle differentiation process, in particular modifications of cell–cell contact, cell adhesion, and plasma membrane…”
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Human sialidase NEU4 long and short are extrinsic proteins bound to outer mitochondrial membrane and the endoplasmic reticulum, respectively
Published in Glycobiology (Oxford) (01-02-2010)“…Sialidases are widely distributed glycohydrolytic enzymes removing sialic acid residues from glycoconjugates. In mammals, several sialidases with different…”
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Identification of lysosomal sialidase NEU1 and plasma membrane sialidase NEU3 in human erythrocytes
Published in Journal of cellular biochemistry (01-01-2013)“…The sialylation level of molecules, sialoglycoproteins and gangliosides, protruding from plasma membranes regulates multiple facets of erythrocyte function,…”
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Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures
Published in Biochemical journal (01-12-2007)“…Sialidase NEU3 is also known as the plasma-membrane-associated form of mammalian sialidases, exhibiting a high substrate specificity towards gangliosides. In…”
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Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle
Published in Cell death and differentiation (01-12-2006)“…Stem cells hold a great potential for the regeneration of damaged tissues in cardiovascular or musculoskeletal diseases. Unfortunately, problems such as…”
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NEU3 Sialidase Strictly Modulates GM3 Levels in Skeletal Myoblasts C2C12 Thus Favoring Their Differentiation and Protecting Them from Apoptosis
Published in The Journal of biological chemistry (26-12-2008)“…Membrane-bound sialidase NEU3, often referred to as the “ganglioside sialidase,” has a critical regulatory function on the sialoglycosphingolipid pattern of…”
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Expression of Sialidase Neu2 in Leukemic K562 Cells Induces Apoptosis by Impairing Bcr-Abl/Src Kinases Signaling
Published in The Journal of biological chemistry (11-05-2007)“…Chronic myeloid leukemia is a hematopoietic stem cell cancer, originated by the perpetually “switched on” activity of the tyrosine kinase Bcr-Abl, leading to…”
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The Plasma Membrane-associated Sialidase MmNEU3 Modifies the Ganglioside Pattern of Adjacent Cells Supporting Its Involvement in Cell-to-Cell Interactions
Published in The Journal of biological chemistry (23-04-2004)“…We describe herein the enzyme behavior of MmNEU3, the plasma membrane-associated sialidase from mouse (Mus musculus). MmNEU3 is localized at the plasma…”
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