Search Results - "TERRY, Linda A"

Isolation of prion with BSE properties from farmed goat by Spiropoulos, John, Lockey, Richard, Sallis, Rosemary E, Terry, Linda A, Thorne, Leigh, Holder, Thomas M, Beck, Katy E, Simmons, Marion M

“…Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that include variant Creutzfeldt-Jakob disease in humans, scrapie in small…”
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Environmental Sources of Scrapie Prions by MADDISON, Ben C, BAKER, Claire A, TERRY, Linda A, BELLWORTHY, Susan J, THORNE, Leigh, REES, Helen C, GOUGH, Kevin C

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Prions Are Secreted into the Oral Cavity in Sheep with Preclinical Scrapie by Maddison, Ben C., Rees, Helen C., Baker, Claire A., Taema, Maged, Bellworthy, Susan J., Thorne, Leigh, Terry, Linda A., Gough, Kevin C.

“…A major concern in prion disease transmission is the spread of the disease agent by means of secretions and excretions. We analyzed buccal swab samples…”
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Experimental oral transmission of atypical scrapie to sheep by Simmons, Marion M, Moore, S Jo, Konold, Timm, Thurston, Lisa, Terry, Linda A, Thorne, Leigh, Lockey, Richard, Vickery, Chris, Hawkins, Stephen A C, Chaplin, Melanie J, Spiropoulos, John

“…To investigate the possibility of oral transmission of atypical scrapie in sheep and determine the distribution of infectivity in the animals' peripheral…”
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Oral Secretion of Infectious Scrapie Prions Occurs in Preclinical Sheep with a Range of PRNP Genotypes by Gough, Kevin C, Baker, Claire A, Rees, Helen C, Terry, Linda A, Spiropoulos, John, Thorne, Leigh, Maddison, Ben C

“…Preclinical sheep with the highly scrapie-susceptible VRQ/VRQ PRNP genotype secrete prions from the oral cavity. In order to further understand the…”
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Detection of prions in the faeces of sheep naturally infected with classical scrapie by Terry, Linda A, Howells, Laurence, Bishop, Keith, Baker, Claire A, Everest, Sally, Thorne, Leigh, Maddison, Ben C, Gough, Kevin C

“…Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence…”
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Detection of prion protein particles in blood plasma of scrapie infected sheep by Bannach, Oliver, Birkmann, Eva, Reinartz, Elke, Jaeger, Karl-Erich, Langeveld, Jan P M, Rohwer, Robert G, Gregori, Luisa, Terry, Linda A, Willbold, Dieter, Riesner, Detlev

“…Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not…”
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Strain typing of classical scrapie by transgenic mouse bioassay using protein misfolding cyclic amplification to replace primary passage by Beck, Katy E, Thorne, Leigh, Lockey, Richard, Vickery, Christopher M, Terry, Linda A, Bujdoso, Raymond, Spiropoulos, John

“…According to traditional murine bioassay methodology, prions must be serially passaged within a new host before a stable phenotype, and therefore a strain, can…”
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Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy by Everest, Sally J, Ramsay, Andrew M, Chaplin, Melanie J, Everitt, Sharon, Stack, Michael J, Neale, Michael H, Jeffrey, Martin, Moore, S Jo, Bellworthy, Susan J, Terry, Linda A

“…Prions are largely contained within the nervous and lymphoid tissue of transmissible spongiform encephalopathy (TSE) infected animals. However, following…”
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The interpretation of disease phenotypes to identify TSE strains following murine bioassay: characterisation of classical scrapie by Beck, Katy E, Vickery, Christopher M, Lockey, Richard, Holder, Thomas, Thorne, Leigh, Terry, Linda A, Denyer, Margaret, Webb, Paul, Simmons, Marion M, Spiropoulos, John

“…Mouse bioassay can be readily employed for strain typing of naturally occurring transmissible spongiform encephalopathy cases. Classical scrapie strains have…”
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Use of Murine Bioassay to Resolve Ovine Transmissible Spongiform Encephalopathy Cases Showing a Bovine Spongiform Encephalopathy Molecular Profile by Beck, Katy E., Sallis, Rosemary E., Lockey, Richard, Vickery, Christopher M., Béringue, Vincent, Laude, Hubert, Holder, Thomas M., Thorne, Leigh, Terry, Linda A., Tout, Anna C., Jayasena, Dhanushka, Griffiths, Peter C., Cawthraw, Saira, Ellis, Richard, Balkema-Buschmann, Anne, Groschup, Martin H., Simmons, Marion M., Spiropoulos, John

“…Two cases of unusual transmissible spongiform encephalopathy (TSE) were diagnosed on the same farm in ARQ/ARQ PrP sheep showing attributes of both bovine…”
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In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie by Thorne, Leigh, Terry, Linda A

“…Department of Molecular Pathogenesis and Genetics, Veterinary Laboratories Agency, New Haw, Addlestone, Surrey KT15 3NB, UK Correspondence Linda A. Terry…”
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In vitro amplification of PrP(Sc) derived from the brain and blood of sheep infected with scrapie by Thorne, Leigh, Terry, Linda A

“…Scrapie is a fatal, naturally transmissible, neurodegenerative prion disease that affects sheep and goats and is characterized by the accumulation of a…”
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Molecular Profiling of Ovine Prion Diseases by Using Thermolysin-Resistant PrPSc and Endogenous C2 PrP Fragments by OWEN, Jonathan P, REES, Helen C, MADDISON, Ben C, TERRY, Linda A, THORNE, Leigh, JACKMAN, Roy, WHITELAM, Garry C, GOUGH, Kevin C

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Inactivation of H‐type and L‐type bovine spongiform encephalopathy following recommended autoclave decontamination procedures by Chapman, Gail E., Lockey, Richard, Beck, Katy E., Vickery, Chris, Arnold, Mark, Thorne, Leigh, Thorne, Jemma K., Walker, Sarah R., Keulen, Lucien, Casalone, Cristina, Griffiths, Peter C., Simmons, Marion M., Terry, Linda A., Spiropoulos, John

“…The resistance of H‐type and L‐type BSE prions to autoclaving under EU regulation conditions for specified risk material is unknown. We employed transgenic…”
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Incomplete inactivation of atypical scrapie following recommended autoclave decontamination procedures by Spiropoulos, John, Lockey, Richard, Beck, Katy E., Vickery, Chris, Holder, Thomas M., Thorne, Leigh, Arnold, Mark, Andreoletti, Olivier, Simmons, Marion M., Terry, Linda A.

“…Prions are highly resistant to the decontamination procedures normally used to inactivate conventional pathogens. This is a challenging problem not only in the…”
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PrPSc is associated with B cells in the blood of scrapie-infected sheep by Edwards, Jane C, Moore, S. Jo, Hawthorn, Jeremy A, Neale, Michael H, Terry, Linda A

“…Abstract Recently, we reported that PrPSc , a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep…”
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PrP(Sc) is associated with B cells in the blood of scrapie-infected sheep by Edwards, Jane C, Moore, S Jo, Hawthorn, Jeremy A, Neale, Michael H, Terry, Linda A

“…Recently, we reported that PrP(Sc), a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep using a…”
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Evidence of effective scrapie transmission via colostrum and milk in sheep by Konold, Timm, Moore, S Jo, Bellworthy, Susan J, Terry, Linda A, Thorne, Leigh, Ramsay, Andrew, Salguero, F Javier, Simmons, Marion M, Simmons, Hugh A

“…BACKGROUND: Evidence for scrapie transmission from VRQ/VRQ ewes to lambs via milk was first reported in 2008 but in that study there were concerns that lateral…”
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Detection and Localisation of PrPSc in the Liver of Sheep Infected with Scrapie and Bovine Spongiform Encephalopathy by Everest, Sally J., Ramsay, Andrew M., Chaplin, Melanie J., Everitt, Sharon, Stack, Michael J., Neale, Michael H., Jeffrey, Martin, Moore, S. Jo, Bellworthy, Susan J., Terry, Linda A.

“…Prions are largely contained within the nervous and lymphoid tissue of transmissible spongiform encephalopathy (TSE) infected animals. However, following…”
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