Search Results - "TERAMI, Takahiro"
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Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex
Published in Diabetes (New York, N.Y.) (01-11-2012)“…It is unknown whether adipokines derived from adipose tissues modulate endoplasmic reticulum (ER) stress induced in obesity. Here, we show that visceral…”
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Visceral Adipose Tissue-derived Serine Proteinase Inhibitor Inhibits Apoptosis of Endothelial Cells as a Ligand for the Cell-Surface GRP78/Voltage-dependent Anion Channel Complex
Published in Circulation research (01-03-2013)“…RATIONALE:Visceral adipose tissue-derived serine proteinase inhibitor (vaspin) is an adipokine identified from visceral adipose tissues of genetically obese…”
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Urinary fetuin-A is a novel marker for diabetic nephropathy in type 2 diabetes identified by lectin microarray
Published in PloS one (15-10-2013)“…We analyzed the urine samples of patients with type 2 diabetes at various stages of diabetic nephropathy by lectin microarray to identify a biomarker to…”
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Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes
Published in Metabolism, clinical and experimental (01-06-2015)“…Abstract Objective In obesity and type 2 diabetes, the impairment of mitochondrial function in white adipose tissue (WAT) is linked to a reduction in whole…”
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Pemt deficiency ameliorates endoplasmic reticulum stress in diabetic nephropathy
Published in PloS one (25-03-2014)“…Phosphatidylethanolamine N-methyltransferase (Pemt) catalyzes the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) mainly in the liver…”
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Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease
Published in BMC nephrology (22-01-2013)“…Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1…”
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RXR antagonism induces G0/G1 cell cycle arrest and ameliorates obesity by up-regulating the p53-p21$^{rm{Cip1}}$ pathway in adipocytes
Published in The Journal of pathology (01-04-2012)“…The peroxisome proliferator activated receptor‐γ (PPARγ) agonist, pioglitazone (PIO), exerts anti‐diabetic properties associated with increased fat mass,…”
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A Case of Type 2 Diabetes and Metastatic Liver Cancer Exhibiting Hypercholesterolemia with Abnormal Lipoproteins
Published in Internal Medicine (01-01-2012)“…Although the appearance of abnormal lipoproteins in liver diseases is well known, the precise analyses of abnormal lipoproteins remain elusive. Here, we report…”
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Galectin-9 and T Cell Immunoglobulin Mucin-3 Pathway Is a Therapeutic Target for Type 1 Diabetes
Published in Endocrinology (Philadelphia) (01-02-2012)“…Galectin-9 (Gal-9), a ligand for T cell Ig mucin-3 (Tim-3), induces apoptosis in cluster of differentiation 4 (CD4)+ Tim-3+ T helper 1 (TH1) cells via the…”
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Serum Vaspin Concentrations Are Closely Related to Insulin Resistance, and rs77060950 at SERPINA12 Genetically Defines Distinct Group with Higher Serum Levels in Japanese Population
Published in The journal of clinical endocrinology and metabolism (01-07-2012)“…Context: Vaspin is an adipokine with insulin-sensitizing effects identified from visceral adipose tissues of genetically obese rats. Objective: We investigated…”
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RXR antagonism induces G 0 /G 1 cell cycle arrest and ameliorates obesity by up‐regulating the p53–p21$^{\rm{Cip1}}$ pathway in adipocytes
Published in The Journal of pathology (01-04-2012)“…The peroxisome proliferator activated receptor‐γ (PPARγ) agonist, pioglitazone (PIO), exerts anti‐diabetic properties associated with increased fat mass,…”
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Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes
Published in International journal of nephrology and renovascular disease (2013)“…Urinary angiotensinogen has been reported as a marker for the activation of intrarenal renin-angiotensin system (RAS) in various kidney diseases. To…”
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Urinary Fetuin-A Is a Novel Marker for Diabetic Nephropathy in Type 2 Diabetes Identified by Lectin Microarray: e77118
Published in PloS one (01-10-2013)“…We analyzed the urine samples of patients with type 2 diabetes at various stages of diabetic nephropathy by lectin microarray to identify a biomarker to…”
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Two novel mutations of lecithin:cholesterol acyltransferase (LCAT) gene and the influence of APOE genotypes on clinical manifestations
Published in NDT plus (01-10-2011)“…Familial lecithin:cholesterol acyltransferase deficiency (FLD) is an autosomal recessive disorder characterized by corneal opacity, hemolytic anemia, low…”
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