Search Results - "TERABE, Masaki"

Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells by Ma, Chi, Han, Miaojun, Heinrich, Bernd, Fu, Qiong, Zhang, Qianfei, Sandhu, Milan, Agdashian, David, Terabe, Masaki, Berzofsky, Jay A, Fako, Valerie, Ritz, Thomas, Longerich, Thomas, Theriot, Casey M, McCulloch, John A, Roy, Soumen, Yuan, Wuxing, Thovarai, Vishal, Sen, Shurjo K, Ruchirawat, Mathuros, Korangy, Firouzeh, Wang, Xin Wei, Trinchieri, Giorgio, Greten, Tim F

“…Primary liver tumors and liver metastasis currently represent the leading cause of cancer-related death. Commensal bacteria are important regulators of…”
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Tissue-Specific Roles of NKT Cells in Tumor Immunity by Terabe, Masaki, Berzofsky, Jay A

“…NKT cells are an unusual population of T cells recognizing lipids presented by CD1d, a non-classical class-I-like molecule, rather than peptides presented by…”
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Labeling Extracellular Vesicles for Nanoscale Flow Cytometry by Morales-Kastresana, Aizea, Telford, Bill, Musich, Thomas A., McKinnon, Katherine, Clayborne, Cassandra, Braig, Zach, Rosner, Ari, Demberg, Thorsten, Watson, Dionysios C., Karpova, Tatiana S., Freeman, Gordon J., DeKruyff, Rosemarie H., Pavlakis, George N., Terabe, Masaki, Robert-Guroff, Marjorie, Berzofsky, Jay A., Jones, Jennifer C.

“…Extracellular vesicles (EVs), including exosomes and microvesicles, are 30–800 nm vesicles that are released by most cell types, as biological packages for…”
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The immunoregulatory role of type I and type II NKT cells in cancer and other diseases by Terabe, Masaki, Berzofsky, Jay A.

“…NKT cells are CD1d-restricted T cells that recognize lipid antigens. They also have been shown to play critical roles in the regulation of immune responses. In…”
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Altered Lipid Tumor Environment and Its Potential Effects on NKT Cell Function in Tumor Immunity by Tiwary, Shweta, Berzofsky, Jay A, Terabe, Masaki

“…Natural killer T (NKT) cells are CD1d restricted T cells that mostly recognize lipid antigens. These cells share characteristics with both adaptive and innate…”
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Making a Cold Tumor Hot: The Role of Vaccines in the Treatment of Glioblastoma by Frederico, Stephen C, Hancock, John C, Brettschneider, Emily E S, Ratnam, Nivedita M, Gilbert, Mark R, Terabe, Masaki

“…The use of immunotherapies for the treatment of brain tumors is a topic that has garnered considerable excitement in recent years. Discoveries such as the…”
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Chapter 8 The Role of NKT Cells in Tumor Immunity by Terabe, Masaki, Berzofsky, Jay A.

“…NKT cells are a relatively newly recognized member of the immune community, with profound effects on the rest of the immune system despite their small numbers…”
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NKT Cells in Tumor Immunity: Opposing Subsets Define a New Immunoregulatory Axis by Berzofsky, Jay A, Terabe, Masaki

“…NKT cells are true Ag-specific T cells that also have innate properties and form a bridge between the innate and adaptive immune systems. Distinct NKT cell…”
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NKT cell networks in the regulation of tumor immunity by Robertson, Faith C, Berzofsky, Jay A, Terabe, Masaki

“…CD1d-restricted natural killer T (NKT) cells lie at the interface between the innate and adaptive immune systems and are important mediators of immune…”
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Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients by Castiello, Luciano, Sabatino, Marianna, Ren, Jiaqiang, Terabe, Masaki, Khuu, Hanh, Wood, Lauren V, Berzofsky, Jay A, Stroncek, David F

“…Despite the vast number of clinical trials conducted so far, dendritic cell (DC)-based cancer vaccines have mostly shown unsatisfactory results. Factors and…”
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The contrasting roles of NKT cells in tumor immunity by Berzofsky, Jay A, Terabe, Masaki

“…NKT cells are true T cells that serve as a bridge between the innate and adaptive immune system, acting as first responders. They recognize lipid antigens…”
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Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy by Terabe, Masaki, Robertson, Faith C., Clark, Katharine, De Ravin, Emma, Bloom, Anja, Venzon, David J., Kato, Shingo, Mirza, Amer, Berzofsky, Jay A.

“…Checkpoint inhibition has established immunotherapy as a major modality of cancer treatment. However, the success of cancer immunotherapy is still limited as…”
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Possible Therapeutic Application of Targeting Type II Natural Killer T Cell-Mediated Suppression of Tumor Immunity by Kato, Shingo, Berzofsky, Jay A, Terabe, Masaki

“…Natural killer T (NKT) cells are a unique T cell subset that exhibits characteristics from both the innate immune cells and T cells. There are at least two…”
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The Role of NKT Cells in Glioblastoma by Brettschneider, Emily E. S., Terabe, Masaki

“…Glioblastoma is an aggressive and deadly cancer, but to date, immunotherapies have failed to make significant strides in improving prognoses for glioblastoma…”
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Cross-Regulation between Type I and Type II NKT Cells in Regulating Tumor Immunity: A New Immunoregulatory Axis by Ambrosino, Elena, Terabe, Masaki, Halder, Ramesh C, Peng, Judy, Takaku, Shun, Miyake, Sachiko, Yamamura, Takashi, Kumar, Vipin, Berzofsky, Jay A

“…Negative immunoregulation is a major barrier to successful cancer immunotherapy. The NKT cell is known to be one such regulator. In this study we explored the…”
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A nonclassical non-Vα14Jα18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance by Terabe, Masaki, Swann, Jeremy, Ambrosino, Elena, Sinha, Pratima, Takaku, Shun, Hayakawa, Yoshihiro, Godfrey, Dale I., Ostrand-Rosenberg, Suzanne, Smyth, Mark J., Berzofsky, Jay A.

“…The importance of immunoregulatory T cells has become increasingly apparent. Both CD4+CD25+ T cells and CD1d-restricted NKT cells have been reported to…”
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Synergistic Enhancement of CD8+ T Cell–Mediated Tumor Vaccine Efficacy by an Anti–Transforming Growth Factor-β Monoclonal Antibody by Terabe, Masaki, Ambrosino, Elena, Takaku, Shun, O'Konek, Jessica J, Venzon, David, Lonning, Scott, McPherson, John M, Berzofsky, Jay A

“…Purpose: Transforming growth factor-β (TGF-β) is an immunosuppressive cytokine, having direct suppressive activity against conventional CD4 + and CD8 + T cells…”
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Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response by Stirling, Elizabeth R, Terabe, Masaki, Wilson, Adam S, Kooshki, Mitra, Yamaleyeva, Liliya M, Alexander-Miller, Martha A, Zhang, Wei, Miller, Lance D, Triozzi, Pierre L, Soto-Pantoja, David R

“…BackgroundCD47 is an integral membrane protein that alters adaptive immunosurveillance when bound to the matricellular glycoprotein thrombospondin-1 (TSP1). We…”
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Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques by Sui, Yongjun, Zhu, Qing, Gagnon, Susan, Dzutsev, Amiran, Terabe, Masaki, Vaccari, Monica, Venzon, David, Klinman, Dennis, Strober, Warren, Kelsall, Brian, Franchini, Genoveffa, Belyakov, Igor M, Berzofsky, Jay A

“…Adjuvant effects on innate as well as adaptive immunity may be critical for inducing protection against mucosal HIV and simian immunodeficiency virus (SIV)…”
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IL-15 as a mediator of CD4⁺ help for CD8⁺ T cell longevity and avoidance of TRAIL-mediated apoptosis by Oh, SangKon, Perera, Liyanage P, Terabe, Masaki, Ni, Ling, Waldmann, Thomas A, Berzofsky, Jay A

“…CD4⁺ helper T cells contribute to the induction and maintenance of antigen-specific CD8⁺ T cells. Their absence results in short-lived antigen-specific CD8⁺ T…”
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