Search Results - "TEO, Ian"

Transitioning from a foundation studies program to university: a study of mainland Chinese students by Teo, Ian, Arkoudis, Sophia

“…Foundations studies programs (FSPs), sometimes termed pathways programs, seek to prepare international students for an undergraduate education. While…”
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Rapid, centralised decision-making in a higher education emergency by Freeman, Brigid, Leihy, Peodair, Teo, Ian, Kim, Dong Kwang

“…Purpose This study aims to explain the primacy that rapid, centralised decision-making gained in higher education institutions during the COVID-19 pandemic,…”
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Nebulised amphotericin B-polymethacrylic acid nanoparticle prophylaxis prevents invasive aspergillosis by Shirkhani, Khojasteh, PhD, Teo, Ian, PhD, Armstrong-James, Darius, MD, PhD, Shaunak, Sunil, MD, PhD

“…Abstract Aspergillus species are the major life threatening fungal pathogens in transplant patients. Germination of inhaled fungal spores initiates infection,…”
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Site-specific PEGylation of native disulfide bonds in therapeutic proteins by Shaunak, Sunil, Brocchini, Steve, Godwin, Antony, Choi, Ji-Won, Balan, Sibu, Pedone, Elisa, Vijayarangam, Damotharan, Heidelberger, Sibylle, Teo, Ian, Zloh, Mire

“…Native disulfide bonds in therapeutic proteins are crucial for tertiary structure and biological activity and are therefore considered unsuitable for chemical…”
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Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses by Barata, Teresa S, Teo, Ian, Brocchini, Steve, Zloh, Mire, Shaunak, Sunil

“…The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available…”
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Site-Specific PEGylation of Protein Disulfide Bonds Using a Three-Carbon Bridge by Balan, Sibu, Choi, Ji-won, Godwin, Antony, Teo, Ian, Laborde, Carlos M, Heidelberger, Sibylle, Zloh, Mire, Shaunak, Sunil, Brocchini, Steve

“…The covalent conjugation of a functionalized poly(ethylene glycol) (PEG) to multiple nucleophilic amine residues results in a heterogeneous mixture of PEG…”
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Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers by Teo, Ian, Toms, Steve M., Marteyn, Benoit, Barata, Teresa S., Simpson, Peter, Johnston, Karen A., Schnupf, Pamela, Puhar, Andrea, Bell, Tracey, Tang, Chris, Zloh, Mire, Matthews, Steve, Rendle, Phillip M., Sansonetti, Philippe J., Shaunak, Sunil

“…Intestinal pathogens use the host's excessive inflammatory cytokine response, designed to eliminate dangerous bacteria, to disrupt epithelial gut wall…”
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Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy by Stevenson, Mario, Sharkey, Mark E, Teo, Ian, Greenough, Thomas, Sharova, Natalia, Luzuriaga, Katherine, Sullivan, John L, Bucy, R. Pat, Kostrikis, Leondios G, Haase, Ashley, Veryard, Claire, Davaro, Raul E, Cheeseman, Sarah H, Daly, Jennifer S, Bova, Carol, Ellison, Richard T, Mady, Brian, Lai, Kwan Kew, Moyle, Graeme, Nelson, Mark, Gazzard, Brian, Shaunak, Sunil

“…Treatment of HIV-1-infected individuals with a combination of anti-retroviral agents results in sustained suppression of HIV-1 replication, as evidenced by a…”
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Identification of two mutually exclusive groups after long-term monitoring of HIV DNA 2-LTR circle copy number in patients on HAART by MORLESE, John, TEO, Ian A, CHOI, Ji-Won, GAZZARD, Brian, SHAUNAK, Sunil

“…Anti-retroviral drug therapy reduces but does not abolish HIV transmission and replication throughout the body. HIV DNA 2-long terminal repeat (2-LTR) circles…”
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A policy monitoring framework to prepare for, respond to, and recover from education in emergencies by Tarricone, Pina, Mestan, Kemran, Teo, Ian

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Republic of Singapore Air Force Helicopter Search-and-Rescue and Medical Evacuations: A 5-Year Review by Yuan, Jing, Go, Lih Khuang, Ang, Xue Qi Tabitha, Teo, Ian Shern Zachary, Soh, Feng Wei

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Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid by Corware, Karina, Harris, Debra, Teo, Ian, Rogers, Matthew, Naresh, Kikkeri, Müller, Ingrid, Shaunak, Sunil

“…Abstract Cutaneous leishmaniasis (CL) is a neglected tropical disease that causes prominent skin scaring. No water soluble, non-toxic, short course and low…”
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Systemic cytokine storm in severe eosinophilic dermatitis by Singanayagam, Anika, Lamb, Lucy, Makinde, Julia E, Teo, Ian, Shaunak, Sunil

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Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation by Shaunak, Sunil, Thomas, Sharyn, Gianasi, Elisabetta, Godwin, Antony, Jones, Emma, Teo, Ian, Mireskandari, Kamiar, Luthert, Philip, Duncan, Ruth, Patterson, Steve, Khaw, Peng, Brocchini, Steve

“…Dendrimers are hyperbranched macromolecules that can be chemically synthesized to have precise structural characteristics. We used anionic, polyamidoamine,…”
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Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex by Barata, Teresa, Teo, Ian, Lalwani, Sanjiv, Simanek, Eric, Zloh, Mire, Shaunak, Sunil

“…Abstract The cell surface interaction between bacterial lipopolysaccharide (LPS), Toll-like receptor 4 (TLR4) and MD-2 is central to bacterial sepsis syndromes…”
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The intracellular signal for induction of resistance to alkylating agents in E. coli by Teo, I, Sedgwick, B, Kilpatrick, M W, McCarthy, T V, Lindahl, T

“…The E. coli ada gene positively controls its own expression and that of other genes (alkA, alkB, aidB) involved in repair of DNA alkylation damage. The cloned…”
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Controlling the cytokine storm in severe bacterial diarrhoea with an oral Toll‐like receptor 4 antagonist by Islam, Dilara, Lombardini, Eric, Ruamsap, Nattaya, Imerbsin, Rawiwan, Khantapura, Patchariya, Teo, Ian, Neesanant, Pimmnapar, Gonwong, Siriphan, Yongvanitchit, Kosol, Swierczewski, Brett E., Mason, Carl J., Shaunak, Sunil

“…Summary Shigella dysenteriae causes the most severe of all infectious diarrhoeas and colitis. We infected rhesus macaques orally and also treated them orally…”
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Controlling the cytokine storm in severe bacterial diarrhoea with an oral T oll‐like receptor 4 antagonist by Islam, Dilara, Lombardini, Eric, Ruamsap, Nattaya, Imerbsin, Rawiwan, Khantapura, Patchariya, Teo, Ian, Neesanant, Pimmnapar, Gonwong, Siriphan, Yongvanitchit, Kosol, Swierczewski, Brett E., Mason, Carl J., Shaunak, Sunil

“…Summary Shigella dysenteriae causes the most severe of all infectious diarrhoeas and colitis. We infected rhesus macaques orally and also treated them orally…”
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Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers by Barata, Teresa Silva, Shaunak, Sunil, Teo, Ian, Zloh, Mire, Brocchini, Steve

“…The partial modification of carboxylic acid terminated polyamidoamine (PAMAM) dendrimers with glucosamine has been reported to give dendrimer glucosamine…”
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From sequence to 3D structure of hyperbranched molecules: application to surface modified PAMAM dendrimers by Barata, Teresa S., Brocchini, Steve, Teo, Ian, Shaunak, Sunil, Zloh, Mire

“…The molecular modeling of hyperbranched molecules is currently constrained by difficulties in model building, due partly to lack of parameterization of their…”
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