Search Results - "TEO, Audrey S. M"

OPTIMA: sensitive and accurate whole-genome alignment of error-prone genomic maps by combinatorial indexing and technology-agnostic statistical analysis by Verzotto, Davide, M Teo, Audrey S, Hillmer, Axel M, Nagarajan, Niranjan

“…Resolution of complex repeat structures and rearrangements in the assembly and analysis of large eukaryotic genomes is often aided by a combination of…”
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Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing by Nahar, Rahul, Zhai, Weiwei, Zhang, Tong, Takano, Angela, Khng, Alexis J., Lee, Yin Yeng, Liu, Xingliang, Lim, Chong Hee, Koh, Tina P. T., Aung, Zaw Win, Lim, Tony Kiat Hon, Veeravalli, Lavanya, Yuan, Ju, Teo, Audrey S. M., Chan, Cheryl X., Poh, Huay Mei, Chua, Ivan M. L., Liew, Audrey Ann, Lau, Dawn Ping Xi, Kwang, Xue Lin, Toh, Chee Keong, Lim, Wan-Teck, Lim, Bing, Tam, Wai Leong, Tan, Eng-Huat, Hillmer, Axel M., Tan, Daniel S. W.

“…EGFR -mutant lung adenocarcinomas (LUAD) display diverse clinical trajectories and are characterized by rapid but short-lived responses to EGFR tyrosine kinase…”
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An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia by Ko, Tun Kiat, Javed, Asif, Lee, Kian Leong, Pathiraja, Thushangi N., Liu, Xingliang, Malik, Simeen, Soh, Sheila Xinxuan, Heng, Xiu Ting, Takahashi, Naoto, Tan, Joanna H.J., Bhatia, Ravi, Khng, Alexis J., Chng, Wee-Joo, Sia, Yee Yen, Fruman, David A., Ng, King Pan, Chan, Zhu En, Xie, Kim Jiajing, Hoi, Qiangze, Chan, Cheryl Xueli, Teo, Audrey S.M., Velazquez Camacho, Oscar, Meah, Wee Yang, Khor, Chiea Chuen, Ong, Chin Thing J., Soon, Wei Jia W., Tan, Patrick, Ng, Pauline C., Chuah, Charles, Hillmer, Axel M., Ong, S. Tiong

“…Targeted therapies against the BCR-ABL1 kinase have revolutionized treatment of chronic phase (CP) chronic myeloid leukemia (CML). In contrast, management of…”
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Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons by Yao, Fei, Ariyaratne, Pramila N, Hillmer, Axel M, Lee, Wah Heng, Li, Guoliang, Teo, Audrey S M, Woo, Xing Yi, Zhang, Zhenshui, Chen, Jieqi P, Poh, Wan Ting, Zawack, Kelson F B, Chan, Chee Seng, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D, Gao, Song, Nagarajan, Niranjan, Thoreau, Hervé, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Wei, Chia-Lin, Bourque, Guillaume, Sung, Wing-Kin, Liu, Edison T, Ruan, Yijun

“…Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer…”
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Systems consequences of amplicon formation in human breast cancer by Inaki, Koichiro, Menghi, Francesca, Woo, Xing Yi, Wagner, Joel P, Jacques, Pierre-Étienne, Lee, Yi Fang, Shreckengast, Phung Trang, Soon, Wendy WeiJia, Malhotra, Ankit, Teo, Audrey S M, Hillmer, Axel M, Khng, Alexis Jiaying, Ruan, Xiaoan, Ong, Swee Hoe, Bertrand, Denis, Nagarajan, Niranjan, Karuturi, R Krishna Murthy, Miranda, Alfredo Hidalgo, Liu, Edison T

“…Chromosomal structural variations play an important role in determining the transcriptional landscape of human breast cancers. To assess the nature of these…”
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Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line by Teo, Audrey S M, Verzotto, Davide, Yao, Fei, Nagarajan, Niranjan, Hillmer, Axel M

“…Next-generation sequencing (NGS) technologies have changed our understanding of the variability of the human genome. However, the identification of genome…”
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Whole-genome reconstruction and mutational signatures in gastric cancer by Nagarajan, Niranjan, Bertrand, Denis, Hillmer, Axel M, Zang, Zhi Jiang, Yao, Fei, Jacques, Pierre-Étienne, Teo, Audrey SM, Cutcutache, Ioana, Zhang, Zhenshui, Lee, Wah Heng, Sia, Yee Yen, Gao, Song, Ariyaratne, Pramila N, Ho, Andrea, Woo, Xing Yi, Veeravali, Lavanya, Ong, Choon Kiat, Deng, Niantao, Desai, Kartiki V, Khor, Chiea Chuen, Hibberd, Martin L, Shahab, Atif, Rao, Jaideepraj, Wu, Mengchu, Teh, Ming, Zhu, Feng, Chin, Sze Yung, Pang, Brendan, So, Jimmy BY, Bourque, Guillaume, Soong, Richie, Sung, Wing-Kin, Tean Teh, Bin, Rozen, Steven, Ruan, Xiaoan, Yeoh, Khay Guan, Tan, Patrick BO, Ruan, Yijun

“…BACKGROUND: Gastric cancer is the second highest cause of global cancer mortality. To explore the complete repertoire of somatic alterations in gastric cancer,…”
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Specific profiles of house dust mite sensitization in children with asthma and in children with eczema by Shek, Lynette Pei-Chi, Chong, Angeline R., Soh, Shu E., Cheong, Nge, Teo, Audrey S. M., Yi, Fong C., Giam, Yoke C., Chua, Kaw Y., Van Bever, Hugo P.

“…Shek LP, Chong AR, Soh SE, Cheong N, Teo ASM, Yi FC, Giam YC, Chua KY, Van Bever HP. Specific profiles of house dust mite sensitization in children with asthma…”
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Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities by Chua, Khi Pin, Teng, Yvonne H F, Tan, Aaron C, Takano, Angela, Alvarez, Jacob J S, Nahar, Rahul, Rohatgi, Neha, Lai, Gillianne G Y, Aung, Zaw Win, Yeong, Joe P S, Lim, Kiat Hon, Naeini, Marjan Mojtabavi, Kassam, Irfahan, Jain, Amit, Tan, Wan Ling, Gogna, Apoorva, Too, Chow Wei, Kanesvaran, Ravindran, Ng, Quan Sing, Ang, Mei Kim, Rajasekaran, Tanujaa, Anantham, Devanand, Phua, Ghee Chee, Tan, Bien Soo, Lee, Yin Yeng, Wang, Lanying, Teo, Audrey S M, Khng, Alexis Jiaying, Lim, Ming Jie, Suteja, Lisda, Toh, Chee Keong, Lim, Wan-Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Tan, Eng-Huat, Zhai, Weiwei, Hillmer, Axel M, Skanderup, Anders J, Tan, Daniel S W

“…Despite the established role of EGFR tyrosine kinase inhibitors (TKIs) in -mutated NSCLC, drug resistance inevitably ensues, with a paucity of treatment…”
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De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development by Gordon, Christopher T, Xue, Shifeng, Yigit, Gökhan, Filali, Hicham, Chen, Kelan, Rosin, Nadine, Yoshiura, Koh-ichiro, Oufadem, Myriam, Beck, Tamara J, McGowan, Ruth, Magee, Alex C, Altmüller, Janine, Dion, Camille, Thiele, Holger, Gurzau, Alexandra D, Nürnberg, Peter, Meschede, Dieter, Mühlbauer, Wolfgang, Okamoto, Nobuhiko, Varghese, Vinod, Irving, Rachel, Sigaudy, Sabine, Williams, Denise, Ahmed, S Faisal, Bonnard, Carine, Kong, Mung Kei, Ratbi, Ilham, Fejjal, Nawfal, Fikri, Meriem, Elalaoui, Siham Chafai, Reigstad, Hallvard, Bole-Feysot, Christine, Nitschké, Patrick, Ragge, Nicola, Lévy, Nicolas, Tunçbilek, Gökhan, Teo, Audrey S M, Cunningham, Michael L, Sefiani, Abdelaziz, Kayserili, Hülya, Murphy, James M, Chatdokmaiprai, Chalermpong, Hillmer, Axel M, Wattanasirichaigoon, Duangrurdee, Lyonnet, Stanislas, Magdinier, Frédérique, Javed, Asif, Blewitt, Marnie E, Amiel, Jeanne, Wollnik, Bernd, Reversade, Bruno

“…Jeanne Amiel, Bernd Wollnik, Bruno Reversade and colleagues report de novo missense mutations in SMCHD1 in patients with Bosma arhinia microphthalmia syndrome…”
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Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers by Krishnan, Vidhya G, Ebert, Philip J, Ting, Jason C, Lim, Elaine, Wong, Swee-Seong, Teo, Audrey S M, Yue, Yong G, Chua, Hui-Hoon, Ma, Xiwen, Loh, Gary S L, Lin, Yuhao, Tan, Joanna H J, Yu, Kun, Zhang, Shenli, Reinhard, Christoph, Tan, Daniel S W, Peters, Brock A, Lincoln, Stephen E, Ballinger, Dennis G, Laramie, Jason M, Nilsen, Geoffrey B, Barber, Thomas D, Tan, Patrick, Hillmer, Axel M, Ng, Pauline C

“…Asian nonsmoking populations have a higher incidence of lung cancer compared with their European counterparts. There is a long-standing hypothesis that the…”
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TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome by Ribi, Sebastian, Baumhoer, Daniel, Lee, Kristy, Edison, Teo, Audrey S M, Madan, Babita, Zhang, Kang, Kohlmann, Wendy K, Yao, Fei, Lee, Wah Heng, Hoi, Qiangze, Cai, Shaojiang, Woo, Xing Yi, Tan, Patrick, Jundt, Gernot, Smida, Jan, Nathrath, Michaela, Sung, Wing-Kin, Schiffman, Joshua D, Virshup, David M, Hillmer, Axel M

“…Somatic mutations of TP53 are among the most common in cancer and germline mutations of TP53 (usually missense) can cause Li-Fraumeni syndrome (LFS). Recently,…”
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Detection of chromosomal breakpoints in patients with developmental delay and speech disorders by Utami, Kagistia H, Hillmer, Axel M, Aksoy, Irene, Chew, Elaine G Y, Teo, Audrey S M, Zhang, Zhenshui, Lee, Charlie W H, Chen, Pauline J, Seng, Chan Chee, Ariyaratne, Pramila N, Rouam, Sigrid L, Soo, Lim Seong, Yousoof, Saira, Prokudin, Ivan, Peters, Gregory, Collins, Felicity, Wilson, Meredith, Kakakios, Alyson, Haddad, Georges, Menuet, Arnaud, Perche, Olivier, Tay, Stacey Kiat Hong, Sung, Ken W K, Ruan, Xiaoan, Ruan, Yijun, Liu, Edison T, Briault, Sylvain, Jamieson, Robyn V, Davila, Sonia, Cacheux, Valere

“…Delineating candidate genes at the chromosomal breakpoint regions in the apparently balanced chromosome rearrangements (ABCR) has been shown to be more…”
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Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: variable phenotypic expression in three affected sisters from Mexican ancestry by Arteaga, María E, Hunziker, Walter, Teo, Audrey S M, Hillmer, Axel M, Mutchinick, Osvaldo M

“…Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare autosomal recessive renal disease caused by mutations in genes for the tight…”
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Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes by Hillmer, Axel M, Yao, Fei, Inaki, Koichiro, Lee, Wah Heng, Ariyaratne, Pramila N, Teo, Audrey S M, Woo, Xing Yi, Zhang, Zhenshui, Zhao, Hao, Ukil, Leena, Chen, Jieqi P, Zhu, Feng, So, Jimmy B Y, Salto-Tellez, Manuel, Poh, Wan Ting, Zawack, Kelson F B, Nagarajan, Niranjan, Gao, Song, Li, Guoliang, Kumar, Vikrant, Lim, Hui Ping J, Sia, Yee Yen, Chan, Chee Seng, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D, Thoreau, Hervé, Tan, Patrick B O, Shahab, Atif, Ruan, Xiaoan, Bergh, Jonas, Hall, Per, Cacheux-Rataboul, Valère, Wei, Chia-Lin, Yeoh, Khay Guan, Sung, Wing-Kin, Bourque, Guillaume, Liu, Edison T, Ruan, Yijun

“…Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long-span paired-end-tag (PET) sequencing approach…”
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Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel ROS1 fusion gene and PBX1 as prognostic marker by Plum, Patrick S., Hess, Timo, Bertrand, Denis, Morgenstern, Isabelle, Velazquez Camacho, Oscar, Jonas, Christoph, Alidousty, Christina, Wagner, Britta, Roessler, Stephanie, Albrecht, Thomas, Becker, Jessica, Richartz, Vanessa, Holz, Barbara, Hoppe, Sascha, Poh, Huay Mei, Chia, Burton Kuan Hui, Chan, Cheryl Xueli, Pathiraja, Thushangi, Teo, Audrey SM, Marquardt, Jens U., Khng, Alexis, Heise, Michael, Fei, Yao, Thieme, René, Klein, Sebastian, Hong, Jing Han, Dima, Simona O, Popescu, Irinel, Hoppe‐Lotichius, Maria, Buettner, Reinhard, Lautem, Anja, Otto, Gerd, Quaas, Alexander, Nagarajan, Niranjan, Rozen, Steve, Teh, Bin Tean, Goeppert, Benjamin, Drebber, Uta, Lang, Hauke, Tan, Patrick, Gockel, Ines, Schumacher, Johannes, Hillmer, Axel M.

“…Background Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor prognosis owing to limited therapeutic options. The incidence of…”
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Novel mutations in ndh in isoniazid-resistant Mycobacterium tuberculosis isolates by LEE, Ann S. G, TEO, Audrey S. M, WONG, Sin-Yew

“…Novel mutations in NADH dehydrogenase (ndh) were detected in 8 of 84 (9.5%) isoniazid (INH)-resistant isolates (T110A [n = 1], R268H [n = 7]), but not in 22…”
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Expression of the Blomia tropicalis paramyosin Blo t 11 and its immunodominant peptide in insect cells by Teo, Audrey S. M., Ramos, John D. A., Lee, Bee Wah, Cheong, Nge, Chua, Kaw Yan

“…Blo t 11, a dust‐mite (Blomia tropicalis) paramyosin, is an allergen with significant IgE reactivity that has potential as a diagnostic/therapeutic reagent for…”
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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer by Ng, King Pan, Hillmer, Axel M, Chuah, Charles T H, Juan, Wen Chun, Ko, Tun Kiat, Teo, Audrey S M, Ariyaratne, Pramila N, Takahashi, Naoto, Sawada, Kenichi, Fei, Yao, Soh, Sheila, Lee, Wah Heng, Huang, John W J, Allen, John C, Woo, Xing Yi, Nagarajan, Niranjan, Kumar, Vikrant, Thalamuthu, Anbupalam, Poh, Wan Ting, Ang, Ai Leen, Mya, Hae Tha, How, Gee Fung, Yang, Li Yi, Koh, Liang Piu, Chowbay, Balram, Chang, Chia-Tien, Nadarajan, Veera S, Chng, Wee Joo, Than, Hein, Lim, Lay Cheng, Goh, Yeow Tee, Zhang, Shenli, Poh, Dianne, Tan, Patrick, Seet, Ju-Ee, Ang, Mei-Kim, Chau, Noan-Minh, Ng, Quan-Sing, Tan, Daniel S W, Soda, Manabu, Isobe, Kazutoshi, Nöthen, Markus M, Wong, Tien Y, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Sung, Wing-Kin, Tan, Eng Huat, Yatabe, Yasushi, Mano, Hiroyuki, Soo, Ross A, Chin, Tan Min, Lim, Wan-Teck, Ruan, Yijun, Ong, S Tiong

“…Intrinsic resistance to tyrosine kinase inhibitor (TKI) drugs is limiting the progress of targeted cancer therapies. The efficacy of TKIs relies on their…”
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Novel Mutations in ndh in Isoniazid-Resistant Mycobacterium tuberculosisIsolates by Lee, Ann S. G, Teo, Audrey S. M, Wong, Sin-Yew

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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