Search Results - "TEMM, Constance J"
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Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals
Published in Blood (01-03-2007)“…The limited vessel-forming capacity of infused endothelial progenitor cells (EPCs) into patients with cardiovascular dysfunction may be related to a…”
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Stromal heterogeneity may explain increased incidence of metaplastic breast cancer in women of African descent
Published in Nature communications (14-09-2023)“…The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment…”
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Kidney in VHL disease: Early clear cell proliferation occurs in the distal tubular system
Published in Oncology reports (01-12-2022)“…Renal clear cell carcinoma commonly occurs in patients with von Hippel-Lindau disease (VHL). Kidneys of VHL disease patients (VHL kidneys) contain an abundance…”
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Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells
Published in Journal of the American College of Cardiology (16-06-2004)“…We investigated whether a single episode of exercise could acutely increase the numbers of endothelial progenitor cells (EPCs) and cultured/circulating…”
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FAM83A is a potential biomarker for breast cancer initiation
Published in Biomarker research (19-02-2022)“…Family with sequence similarity 83 member A (FAM83A) presents oncogenic properties in several cancers including breast cancer. Recently, we reported FAM83A…”
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Bariatric Surgery-Induced Weight Loss Reduces Hepatic Lipid Peroxidation Levels and Affects Hepatic Cytochrome P-450 Protein Content
Published in Annals of surgery (01-06-2010)“…To evaluate the effects of surgical weight loss on hepatic lipid peroxidation levels and cytochrome P-450 protein expression in patients with nonalcoholic…”
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Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
Published in Circulation (New York, N.Y.) (16-03-2004)“…The delivery of autologous cells to increase angiogenesis is emerging as a treatment option for patients with cardiovascular disease but may be limited by the…”
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Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice
Published in Molecular therapy. Methods & clinical development (16-03-2018)“…Recombinant adeno-associated virus (rAAV)-mediated gene delivery shows promise to transduce the pancreas, but safety/efficacy in a neoplastic context is not…”
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Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study
Published in Modern pathology (01-10-2011)“…TP63 , a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of…”
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Differences in the temporal expression of regulatory growth factors during choroidal neovascular development
Published in Experimental eye research (01-01-2009)“…Although the roles of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and hepatocyte growth factor (HGF) in pathologic…”
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Bidirectional Regulatory Cross-Talk between Cell Context and Genomic Aberrations Shapes Breast Tumorigenesis
Published in Molecular cancer research (01-11-2021)“…Breast cancers are classified into five intrinsic subtypes and 10 integrative clusters based on gene expression patterns and genomic aberrations, respectively…”
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TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Published in Cancer research (Chicago, Ill.) (14-04-2023)“…Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address…”
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Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer
Published in Oncotarget (06-10-2015)“…Y-box binding protein 1 [YBX1] is a multifunctional protein known to facilitate many of the hallmarks of cancer. Elevated levels of YBX1 protein are highly…”
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Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury
Published in American journal of physiology. Renal physiology (01-08-2008)“…Decreased renal blood flow following an ischemic insult contributes to a reduction in glomerular filtration. However, little is known about the underlying…”
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Long-term spironolactone treatment reduces coronary TRPC expression, vasoconstriction, and atherosclerosis in metabolic syndrome pigs
Published in Basic research in cardiology (01-09-2017)“…Coronary transient receptor potential canonical (TRPC) channel expression is elevated in metabolic syndrome (MetS). However, differential contribution of TRPCs…”
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Clinical, histopathologic and molecular features of idiopathic and diabetic nodular mesangial sclerosis in humans
Published in Nephrology, dialysis, transplantation (31-12-2021)“…Abstract Background Idiopathic nodular mesangial sclerosis, also called idiopathic nodular glomerulosclerosis (ING), is a rare clinical entity with an unclear…”
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Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity
Published in Science advances (14-01-2022)“…Preclinical studies of primary cancer cells are typically done after tumors are removed from patients or animals at ambient atmospheric oxygen (O , ~21%)…”
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Aberrant epigenetic and transcriptional events associated with breast cancer risk
Published in Clinical epigenetics (09-02-2022)“…Genome-wide association studies have identified several breast cancer susceptibility loci. However, biomarkers for risk assessment are still missing. Here, we…”
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Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium
Published in American journal of respiratory cell and molecular biology (01-12-2016)“…Airway epithelial CD55 down-regulation occurs in several hypoxia-associated pulmonary diseases, but the mechanism is unknown. Using in vivo and in vitro assays…”
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HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro
Published in Muscle & nerve (01-02-2000)“…Muscle satellite cell activation following injury is essential for muscle repair, and hepatocyte growth factor/scatter factor (HGF) was the first growth factor…”
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