Search Results - "TEMCHURA, Vladimir"

Decorated and Encapsulated: Virus-Like Particles Against Viral Infections by Temchura, Vladimir

“…Despite great progress in the field of vaccine development, outbreaks of emerging pathogens and insufficient immunogenicity of some licensed vaccines call for…”
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Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis by Azizov, Vugar, Dietel, Katharina, Steffen, Franziska, Dürholz, Kerstin, Meidenbauer, Julia, Lucas, Sébastien, Frech, Michael, Omata, Yasunori, Tajik, Narges, Knipfer, Lisa, Kolenbrander, Anne, Seubert, Silvia, Lapuente, Dennis, Sokolova, Maria V., Hofmann, Jörg, Tenbusch, Matthias, Ramming, Andreas, Steffen, Ulrike, Nimmerjahn, Falk, Linker, Ralf, Wirtz, Stefan, Herrmann, Martin, Temchura, Vladimir, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

“…Alcohol consumption is a consistent protective factor for the development of autoimmune diseases such as rheumatoid arthritis (RA). The underlying mechanism…”
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Targeting and activation of antigen-specific B-cells by calcium phosphate nanoparticles loaded with protein antigen by Temchura, Vladimir V, Kozlova, Diana, Sokolova, Viktoriya, Überla, Klaus, Epple, Matthias

“…Abstract Cross-linking of the B-cell receptors of an antigen-specific B-cell is the initial signal for B-cell activation, proliferation, and differentiation…”
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Immunogenicity of Recombinant Lipid-Based Nanoparticle Vaccines: Danger Signal vs. Helping Hand by Temchura, Vladimir, Wagner, Jannik T, Damm, Dominik

“…Infectious diseases are a predominant problem in human health. While the incidence of many pathogenic infections is controlled by vaccines, some pathogens…”
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Antigen-dependent modulation of immune responses to antigen-Fc fusion proteins by Fc-effector functions by Richel, Elie, Wagner, Jannik T., Klessing, Stephan, Di Vincenzo, Riccardo, Temchura, Vladimir, Überla, Klaus

“…BackgroundFc-fusion proteins have been successfully developed for therapeutic purposes, but are also a promising platform for the fast generation and…”
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Inhibitors of Deubiquitinating Enzymes Interfere with the SARS-CoV-2 Papain-like Protease and Block Virus Replication In Vitro by Große, Maximilian, Setz, Christian, Rauch, Pia, Auth, Janina, Morokutti-Kurz, Martina, Temchura, Vladimir, Schubert, Ulrich

“…The ubiquitin proteasome system (UPS), particularly its deubiquitinating enzymes (DUBs), play a key role in the replication cycle of coronaviruses. The…”
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Oriented display of HIV-1 Env trimers by a novel coupling strategy enhances B cell activation and phagocytosis by Di Vincenzo, Riccardo, Beutel, Jannis, Arnold, Philipp, Wang, Yu, Damm, Dominik, Tannig, Pierre, Lux, Anja, Temchura, Vladimir, Eichler, Jutta, Überla, Klaus

“…Conformationally stabilized Env trimers have been developed as antigens for the induction of neutralizing antibodies against HIV-1. However, the…”
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Advantages and Limitations of Integrated Flagellin Adjuvants for HIV-Based Nanoparticle B-Cell Vaccines by Barnowski, Cornelia, Kadzioch, Nicole, Damm, Dominik, Yan, Huimin, Temchura, Vladimir

“…The great advantage of virus-like particle (VLP) nano-vaccines is their structural identity to wild-type viruses, ensuring that antigen-specific B-cells…”
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Application of the PAMONO-Sensor for Quantification of Microvesicles and Determination of Nano-Particle Size Distribution by Shpacovitch, Victoria, Sidorenko, Irina, Lenssen, Jan Eric, Temchura, Vladimir, Weichert, Frank, Müller, Heinrich, Überla, Klaus, Zybin, Alexander, Schramm, Alexander, Hergenröder, Roland

“…The PAMONO-sensor (plasmon assisted microscopy of nano-objects) demonstrated an ability to detect and quantify individual viruses and virus-like particles…”
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HIV-derived lentiviral particles promote T-cell independent activation and differentiation of naïve cognate conventional B2-cells in vitro by Gardt, Oliver, Grewe, Bastian, Tippler, Bettina G, Überla, Klaus, Temchura, Vladimir V

“…Highlights • The direct impact of lentiviral particles on cognate B cells in vitro was shown. • Activation events in B-cells after the contact with lentiviral…”
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Electrostatically Driven Encapsulation of Hydrophilic, Non-Conformational Peptide Epitopes into Liposomes by Suleiman, Ehsan, Damm, Dominik, Batzoni, Mirjam, Temchura, Vladimir, Wagner, Andreas, Überla, Klaus, Vorauer-Uhl, Karola

“…Since the first use of liposomes as carriers for antigens, much work has been done to elucidate the mechanisms involved in the encapsulation of…”
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Conjugation of Native-Like HIV-1 Envelope Trimers onto Liposomes Using EDC/Sulfo-NHS Chemistry: Requirements and Limitations by Suleiman, Ehsan, Mayer, Julia, Lehner, Elisabeth, Kohlhauser, Bianca, Katholnig, Alexandra, Batzoni, Mirjam, Damm, Dominik, Temchura, Vladimir, Wagner, Andreas, Überla, Klaus, Vorauer-Uhl, Karola

“…The display of native-like human immunodeficiency virus type 1 envelope (HIV-1 Env) trimers on liposomes has gained wide attention over the last few years…”
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Protective Efficacy and Immunogenicity of an Adenoviral Vector Vaccine Encoding the Codon-Optimized F Protein of Respiratory Syncytial Virus by KOHLMANN, Rebekka, SCHWANNECKE, Sarah, TIPPLER, Bettina, TERNETTE, Nicola, TEMCHURA, Vladimir V, TENBUSCH, Matthias, ÜBERLA, Klaus, GRUNWALD, Thomas

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus by Temchura, Vladimir V, Tenbusch, Matthias, Nchinda, Godwin, Nabi, Ghulam, Tippler, Bettina, Zelenyuk, Maryna, Wildner, Oliver, Überla, Klaus, Kuate, Seraphin

“…Abstract Exosomes have been proposed as candidates for therapeutic immunization. The present study demonstrates that incorporation of the G protein of…”
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CD4+ T Cells Induced by Tuberculosis Subunit Vaccine H1 Can Improve the HIV-1 Env Humoral Response by Intrastructural Help by Klessing, Stephan, Temchura, Vladimir, Tannig, Pierre, Peter, Antonia Sophia, Christensen, Dennis, Lang, Roland, Überla, Klaus

“…The induction of a potent and long-lasting, broadly neutralizing antibody response is one of the most promising approaches in HIV-1 vaccination. Recently, we…”
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Risk of Immunodeficiency Virus Infection May Increase with Vaccine-Induced Immune Response by TENBUSCH, Matthias, IGNATIUS, Ralf, TEMCHURA, Vladimir, NABI, Ghulam, TIPPLER, Bettina, STEWART-JONES, Guillaume, SALAZAR, Andres M, SAUERMANN, Ulrike, STAHL-HENNIG, Christiane, ÜBERLA, Klaus

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help by Damm, Dominik, Rojas-Sánchez, Leonardo, Theobald, Hannah, Sokolova, Viktoriya, Wyatt, Richard T., Überla, Klaus, Epple, Matthias, Temchura, Vladimir

“…Incorporation of immunodominant T-helper epitopes of licensed vaccines into virus-like particles (VLP) allows to harness T-helper cells induced by the licensed…”
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Modulation of Vaccine-Induced HIV-1-Specific Immune Responses by Co-Electroporation of PD-L1 Encoding DNA by Tannig, Pierre, Peter, Antonia Sophia, Lapuente, Dennis, Klessing, Stephan, Damm, Dominik, Tenbusch, Matthias, Überla, Klaus, Temchura, Vladimir

“…The importance of a balanced T 1/T 2 humoral immune response against the HIV-1 envelope protein (Env) for antibody-mediated HIV-1 control is increasingly…”
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Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2 by Wagner, Jannik T., Müller-Schmucker, Sandra M., Wang, Wenjun, Arnold, Philipp, Uhlig, Nadja, Issmail, Leila, Eberlein, Valentina, Damm, Dominik, Roshanbinfar, Kaveh, Ensser, Armin, Oltmanns, Friederike, Peter, Antonia Sophia, Temchura, Vladimir, Schrödel, Silke, Engel, Felix B., Thirion, Christian, Grunwald, Thomas, Wuhrer, Manfred, Grimm, Dirk, Überla, Klaus

“…Long-acting passive immunization strategies are needed to protect immunosuppressed vulnerable groups from infectious diseases. To further explore this concept…”
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Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes by Damm, Dominik, Suleiman, Ehsan, Theobald, Hannah, Wagner, Jannik T, Batzoni, Mirjam, Ahlfeld Née Kohlhauser, Bianca, Walkenfort, Bernd, Albrecht, Jens-Christian, Ingale, Jidnyasa, Yang, Lifei, Hasenberg, Mike, Wyatt, Richard T, Vorauer-Uhl, Karola, Überla, Klaus, Temchura, Vladimir

“…Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune…”
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