Search Results - "TELLIS, C. C."

Photochemical Nickel-Catalyzed C–H Arylation: Synthetic Scope and Mechanistic Investigations by Heitz, Drew R, Tellis, John C, Molander, Gary A

“…An iridium photocatalyst and visible light facilitate a room temperature, nickel-catalyzed coupling of (hetero)­aryl bromides with activated…”
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Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis by Tellis, John C., Primer, David N., Molander, Gary A.

“…The routine application of Csp3-hybridized nucleophiles in cross-coupling reactions remains an unsolved challenge in organic chemistry. The sluggish…”
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Nickel-Catalyzed Cross-Coupling of Photoredox-Generated Radicals: Uncovering a General Manifold for Stereoconvergence in Nickel-Catalyzed Cross-Couplings by Gutierrez, Osvaldo, Tellis, John C, Primer, David N, Molander, Gary A, Kozlowski, Marisa C

“…The cross-coupling of sp3-hybridized organo­boron reagents via photoredox/​nickel dual catalysis represents a new paradigm of reactivity for engaging…”
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Single-Electron Transmetalation: An Enabling Technology for Secondary Alkylboron Cross-Coupling by Primer, David N, Karakaya, Idris, Tellis, John C, Molander, Gary A

“…Single-electron-mediated alkyl transfer affords a novel mechanism for trans­metal­ation, enabling cross-coupling under mild conditions. Here, general…”
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Protecting group-free, selective cross-coupling of alkyltrifluoroborates with borylated aryl bromides via photoredox/nickel dual catalysis by Yamashita, Yohei, Tellis, John C., Molander, Gary A.

“…Orthogonal reactivity modes offer substantial opportunities for rapid construction of complex small molecules. However, most strategies for imparting…”
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Single-Electron Transmetalation: Synthesis of 1,1-Diaryl-2,2,2-trifluoroethanes by Photoredox/Nickel Dual Catalytic Cross-Coupling by Ryu, DaWeon, Primer, David N., Tellis, John C., Molander, Gary A.

“…Novel methods for the incorporation of fluorinated subunits into organic frameworks are important in pharmaceutical, agrochemical, and materials science…”
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Single-Electron Transmetalation: Protecting-Group-Independent Synthesis of Secondary Benzylic Alcohol Derivatives via Photoredox/Nickel Dual Catalysis by Karimi-Nami, Rahman, Tellis, John C, Molander, Gary A

“…Protecting-group-independent cross-coupling of α-alkoxyalkyl- and α-acyloxyalkyltrifluoroborates with aryl and heteroaryl bromides is achieved through…”
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PCSK9 is minimally associated with HDL but impairs the anti-atherosclerotic HDL effects on endothelial cell activation by Dafnis, Ioannis, Tsouka, Aikaterini N., Gkolfinopoulou, Christina, Tellis, Constantinos C., Chroni, Angeliki, Tselepis, Alexandros D.

“…Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) regulates the cell-surface localization of LDL receptors in hepatocytes and is associated with LDL and…”
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Antibodies against oxidized LDL and atherosclerosis in rheumatoid arthritis patients treated with biological agents: a prospective controlled study by Papamichail, G. V., Georgiadis, A. N., Tellis, C. C., Rapti, I., Markatseli, T. E., Xydis, V. G., Tselepis, A. D., Drosos, A. A., Voulgari, P. V.

“…Objectives The aim of this study was to investigate the relation among atherosclerosis, antibodies against oxidized LDL (anti-oxLDL), and inflammation in…”
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Differential Effect of Omega-3 Fatty Acids on Platelet Inhibition by Antiplatelet Drugs In Vitro by Koutsaliaris, Ioannis K, Pantazi, Despoina, Tsouka, Aikaterini N, Argyropoulou, Ourania, Tellis, Constantinos C, Tselepis, Alexandros D

“…The omega-3 polyunsaturated fatty acids (PUFAs) Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) exert multiple cardioprotective effects, influencing…”
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Amyloid-Beta (1-40) and the Risk of Death From Cardiovascular Causes in Patients With Coronary Heart Disease by Stamatelopoulos, Kimon, MD, Sibbing, Dirk, MD, Rallidis, Loukianos S., MD, Georgiopoulos, Georgios, MD, Stakos, Dimitrios, MD, Braun, Siegmund, MD, Gatsiou, Aikaterini, BSc, Sopova, Kateryna, MD, Kotakos, Christos, MD, Varounis, Christos, MD, Tellis, Constantinos C., PhD, Kastritis, Efstathios, MD, Alevizaki, Maria, MD, Tselepis, Alexandros D., MD, PhD, Alexopoulos, Panagiotis, MD, Laske, Christoph, MD, Keller, Till, MD, Kastrati, Adnan, MD, Dimmeler, Stefanie, PhD, Zeiher, Andreas M., MD, Stellos, Konstantinos, MD

“…Abstract Background The amyloid beta peptide is the major protein constituent of neuritic plaques in Alzheimer disease and appears to play a central role in…”
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Development of a Novel Apigenin Dosage form as a Substitute for the Modern Triple Antithrombotic Regimen by Tsiailanis, Antonios D, Tellis, Constantinos C, Papakyriakopoulou, Paraskevi, Kostagianni, Androniki D, Gkalpinos, Vasileios, Chatzigiannis, Christos M, Kostomitsopoulos, Nikolaos, Valsami, Georgia, Tselepis, Alexandros D, Tzakos, Andreas G

“…The simultaneous administration of three antiplatelet agents has been proposed as an efficient strategy for the secondary prevention of atherothrombotic events…”
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Pleiotropic effects of apolipoprotein C3 on HDL functionality and adipose tissue metabolic activity[S] by Zvintzou, Evangelia, Lhomme, Marie, Chasapi, Stella, Filou, Serafoula, Theodoropoulos, Vassilis, Xapapadaki, Eva, Kontush, Anatol, Spyroulias, George, Tellis, Constantinos C., Tselepis, Alexandros D., Constantinou, Caterina, Kypreos, Kyriakos E.

“…APOC3 is produced mainly by the liver and intestine and approximately half of plasma APOC3 associates with HDL. Though it was believed that APOC3 associates…”
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Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors by Kschonsak, Marc, Jao, Christine C, Arthur, Christopher P, Rohou, Alexis L, Bergeron, Philippe, Ortwine, Daniel F, McKerrall, Steven J, Hackos, David H, Deng, Lunbin, Chen, Jun, Li, Tianbo, Dragovich, Peter S, Volgraf, Matthew, Wright, Matthew R, Payandeh, Jian, Ciferri, Claudio, Tellis, John C

“…The voltage-gated sodium (Na V ) channel Na V 1.7 has been identified as a potential novel analgesic target due to its involvement in human pain syndromes…”
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Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis-Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis-Imidazolines for Protein–Protein Inhibition by Vara, Brandon A, Mayasundari, Anand, Tellis, John C, Danneman, Michael W, Arredondo, Vanessa, Davis, Tyler A, Min, Jaeki, Finch, Kristin, Guy, R. Kiplin, Johnston, Jeffrey N

“…The finding by scientists at Hoffmann-La Roche that cis-imidazolines could disrupt the protein–protein interaction between p53 and MDM2, thereby inducing…”
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A clinical pilot study for the detection of sphingomyelinase in leptospirosis patient's urine at tertiary care hospital by Ashaiba, A., Arun, A.B., Prasad, K. Sudhakara, Tellis, Rouchelle C.

“…Leptospirosis is a perplexing mystification for many clinicians. Clinically often underdiagnosed due to lack of a rapid, sensitive, and specific diagnostic…”
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Urine 8-Hydroxyguanine (8-OHG) in Patients Undergoing Surgery for Colorectal Cancer by Pappas-Gogos, George, Tellis, Constantinos C., Tepelenis, Kostas, Vlachos, Konstantinos, Chrysos, Emmanuel, Tselepis, Alexandros D., Glantzounis, Georgios K.

“…Cellular RNA is less compact than DNA, more easily accessible to ROS and therefore could be more susceptible to oxidative damage. This study was conceived in…”
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Switch to rosuvastatin versus addition of ezetimibe in patients receiving atorvastatin: Effect on urine 8-isoprostane levels by Klouras, E, Tellis, C, Barkas, F, Liberopoulos, E, Elisaf, M, Tselepis, A

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Acute infection with Epstein–Barr virus is associated with atherogenic lipid changes by Apostolou, F, Gazi, I.F, Lagos, K, Tellis, C.C, Tselepis, A.D, Liberopoulos, E.N, Elisaf, M

“…Abstract Objective To evaluate the effects of acute infection with Epstein–Barr virus (infectious mononucleosis, IM) on lipids and lipoproteins. Methods…”
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Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp3–sp2 Cross-Coupling by Tellis, John C, Kelly, Christopher B, Primer, David N, Jouffroy, Matthieu, Patel, Niki R, Molander, Gary A

“…The important role of transition metal-catalyzed cross-coupling in expanding the frontiers of accessible chemical territory is unquestionable. Despite…”
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