Search Results - "TEKOLA AYELE, Fasil"

Pleiotropic genetic influence on birth weight and childhood obesity by Chatterjee, Suvo, Ouidir, Marion, Tekola-Ayele, Fasil

“…Childhood obesity is a global public health problem. Understanding the molecular mechanisms that underlie early origins of childhood obesity can facilitate…”
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Including diverse and admixed populations in genetic epidemiology research by Caliebe, Amke, Tekola‐Ayele, Fasil, Darst, Burcu F., Wang, Xuexia, Song, Yeunjoo E., Gui, Jiang, Sebro, Ronnie A., Balding, David J., Saad, Mohamad, Dubé, Marie‐Pierre

“…The inclusion of ancestrally diverse participants in genetic studies can lead to new discoveries and is important to ensure equitable health care benefit from…”
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Placental multi-omics integration identifies candidate functional genes for birthweight by Tekola-Ayele, Fasil, Zeng, Xuehuo, Chatterjee, Suvo, Ouidir, Marion, Lesseur, Corina, Hao, Ke, Chen, Jia, Tesfaye, Markos, Marsit, Carmen J., Workalemahu, Tsegaselassie, Wapner, Ronald

“…Abnormal birthweight is associated with increased risk for cardiometabolic diseases in later life. Although the placenta is critical to fetal development and…”
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HLA Class II Locus and Susceptibility to Podoconiosis by Tekola Ayele, Fasil, Adeyemo, Adebowale, Finan, Chris, Hailu, Elena, Sinnott, Paul, Burlinson, Natalia Diaz, Aseffa, Abraham, Rotimi, Charles N, Newport, Melanie J, Davey, Gail

“…Podoconiosis is a tropical form of noninfectious lymphedema associated with exposure to red-clay soil. It affects over 4 million people and is associated with…”
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Familial aggregation of stillbirth: A pedigree analysis of a matched case–control study by Workalemahu, Tsegaselassie, Page, Jessica M., Meeks, Huong, Yu, Zhe, Guinto, Emily, Fraser, Alison, Varner, Michael W., Theilen, Lauren H., Quinlan, Aaron, Coon, Hilary, Enquobahrie, Daniel A., Ananth, Cande V., Tekola‐Ayele, Fasil, Jorde, Lynn B., Silver, Robert M.

“…Objective To determine whether stillbirth aggregates in families and quantify its familial risk using extended pedigrees. Design State‐wide matched…”
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Replication of HLA class II locus association with susceptibility to podoconiosis in three Ethiopian ethnic groups by Gebresilase, Tewodros, Finan, Chris, Suveges, Daniel, Tessema, Tesfaye Sisay, Aseffa, Abraham, Davey, Gail, Hatzikotoulas, Konstantinos, Zeggini, Eleftheria, Newport, Melanie J., Tekola-Ayele, Fasil

“…Podoconiosis, a debilitating lymphoedema of the leg, results from barefoot exposure to volcanic clay soil in genetically susceptible individuals. A previous…”
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Burden of podoconiosis in poor rural communities in Gulliso woreda, West Ethiopia by Alemu, Getahun, Tekola Ayele, Fasil, Daniel, Takele, Ahrens, Christel, Davey, Gail

“…Podoconiosis is an environmental lymphoedema affecting people living and working barefoot on irritant red clay soil. Podoconiosis is relatively well described…”
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Prediction of HLA class II alleles using SNPs in an African population by Tekola Ayele, Fasil, Ayele, Fasil Tekola, Hailu, Elena, Finan, Chris, Aseffa, Abraham, Davey, Gail, Newport, Melanie J, Rotimi, Charles N, Adeyemo, Adebowale

“…Despite the importance of the human leukocyte antigen (HLA) gene locus in research and clinical practice, direct HLA typing is laborious and expensive…”
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Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta by Shrestha, Deepika, Workalemahu, Tsegaselassie, Tekola-Ayele, Fasil

“…Disruption of physiological ageing of the placenta is associated with obstetric complications. Altered lipid metabolism is a known trigger of tissue ageing,…”
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Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain by Shrestha, Deepika, Ouidir, Marion, Workalemahu, Tsegaselassie, Zeng, Xuehuo, Tekola-Ayele, Fasil

“…Background Maternal obesity prior to or during pregnancy influences fetal growth, predisposing the offspring to increased risk for obesity across the life…”
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Persistent organic pollutants and gestational diabetes: A multi-center prospective cohort study of healthy US women by Rahman, Mohammad L., Zhang, Cuilin, Smarr, Melissa M., Lee, Sunmi, Honda, Masato, Kannan, Kurunthachalam, Tekola-Ayele, Fasil, Buck Louis, Germaine M.

“…Persistent organic pollutants (POPs) are linked with insulin resistance and type-2 diabetes (T2D) in the general population. However, their associations with…”
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Translational Genomics in Low- and Middle-Income Countries: Opportunities and Challenges by Tekola-Ayele, Fasil, Rotimi, Charles N

“…Translation of genomic discoveries into patient care is slowly becoming a reality in developed economies around the world. In contrast, low- and middle-income…”
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Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth by Habtewold, Tesfa Dejenie, Wijesiriwardhana, Prabhavi, Biedrzycki, Richard J, Tekola-Ayele, Fasil

“…Maternal genetic risk of type 2 diabetes (T2D) has been associated with fetal growth, but the influence of genetic ancestry is not yet fully understood. We…”
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Associations of maternal blood pressure-raising polygenic risk scores with fetal weight by Workalemahu, Tsegaselassie, Rahman, Mohammad L., Ouidir, Marion, Wu, Jing, Zhang, Cuilin, Tekola-Ayele, Fasil

“…Maternal blood pressure (BP) is associated with variations in fetal weight, an important determinant of neonatal and adult health. However, the association of…”
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Prenatal social support in low-risk pregnancy shapes placental epigenome by Tesfaye, Markos, Wu, Jing, Biedrzycki, Richard J, Grantz, Katherine L, Joseph, Paule, Tekola-Ayele, Fasil

“…Poor social support during pregnancy has been linked to inflammation and adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may…”
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Genetic and Environmental Influences on Fetal Growth Vary during Sensitive Periods in Pregnancy by Workalemahu, Tsegaselassie, Grantz, Katherine L., Grewal, Jagteshwar, Zhang, Cuilin, Louis, Germaine M. Buck, Tekola-Ayele, Fasil

“…Aberrant fetal growth is associated with morbidities and mortality during childhood and adult life. Although genetic and environmental factors are known to…”
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High burden of birthweight-lowering genetic variants in Africans and Asians by Tekola-Ayele, Fasil, Workalemahu, Tsegaselassie, Amare, Azmeraw T

“…Birthweight is an important predictor of infant morbidity and mortality, and is associated with cardiovascular diseases, obesity, and diabetes in childhood and…”
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Maternal BMI‐Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups by Shrestha, Deepika, Rahman, Mohammad L., Hinkle, Stefanie N., Workalemahu, Tsegaselassie, Tekola‐Ayele, Fasil

“…Objective Associations between maternal genetic risk for obesity and fetal weight were examined at the end of the first (13 weeks 6 days), second (27 weeks 6…”
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Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy by Tekola-Ayele, Fasil, Zhang, Cuilin, Wu, Jing, Grantz, Katherine L, Rahman, Mohammad L, Shrestha, Deepika, Ouidir, Marion, Workalemahu, Tsegaselassie, Tsai, Michael Y

“…Abnormal fetal growth is a risk factor for infant morbidity and mortality and is associated with cardiometabolic diseases in adults. Genetic influences on…”
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Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth by Tekola-Ayele, Fasil, Ouidir, Marion, Shrestha, Deepika, Workalemahu, Tsegaselassie, Rahman, Mohammad L., Mendola, Pauline, Grantz, Katherine L., Hinkle, Stefanie N., Wu, Jing, Zhang, Cuilin

“…Fetal growth is an important determinant of cardiometabolic disease risk during childhood and adulthood. The genetic architecture of fetal growth remains…”
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