Search Results - "TEICHER, B. A"

The Proteasome Inhibitor PS-341 in Cancer Therapy by TEICHER, B. A, ARA, G, HERBST, R, PALOMBELLA, V. J, ADAMS, J

“…The anticancer activity of the boronic acid dipeptide proteasome inhibitor PS-341 was examined in vitro and in vivo . PS-341 was a potent cytotoxic agent…”
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Antibody-drug conjugate targets by Teicher, B A

“…The requirements for a cell surface molecule to be suitable as an antibody-drug conjugate target are stringent. The notion that antibodies-directed toward…”
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Cryptophycins: a novel class of potent antimitotic antitumor depsipeptides by Shih, C, Teicher, B A

“…The antitumor cryptophycins are synthetic derivatives of the desipeptide cryptophycins isolated from the cyanobacterium Nostoc sp. Cryptophycin 52 that is…”
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A phase II study of high-dose cyclophosphamide, thiotepa, and carboplatin with autologous marrow support in women with measurable advanced breast cancer responding to standard-dose therapy by Antman, K, Ayash, L, Elias, A, Wheeler, C, Hunt, M, Eder, J P, Teicher, B A, Critchlow, J, Bibbo, J, Schnipper, L E

“…The study was designed to determine the duration of complete response (CR) for patients with unresectable or metastatic breast cancer treated with high-dose…”
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Acquired Multicellular-Mediated Resistance to Alkylating Agents in Cancer by Kobayashi, Hiroaki, Man, Shan, Graham, Charles H., Kapitain, Sean J., Teicher, Beverly A., Kerbel, Robert S.

“…EMT-6 murine mammary tumor sublines highly resistant to cyclophosphamide, cis-diamminedichloroplatinum(II), or N,N',N''-triethylenethiophosphoramide were…”
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Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease by TEICHER, B. A, ALVAREZ SOTOMAYOR, E, ZHEN DONG HUANG

“…The formation of a blood supply (angiogenesis) is critical to the growth of solid tumors. The naturally occurring steroid tetrahydrocortisol, the synthetic…”
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Effects of the flavonoid drug quercetin on the response of human prostate tumours to hyperthermia in vitro and in vivo by Asea, A, Ara, G, Teicher, B A, Stevenson, M A, Calderwood, S K

“…Tumour hyperthermia, although potentially a powerful therapeutic agent and radiation sensitizer, is hindered by a number of considerations including…”
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Cyclooxygenase and lipoxygenase inhibitors in cancer therapy by Ara, G., Teicher, B.A.

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Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents by KAKEJI, Y, TEICHER, B. A

“…TNP-740, minocycline, suramin and genistein have demonstrated antiangiogenic activity in various experimental systems. The effect of these agents alone and in…”
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Double dose-intensive chemotherapy with autologous stem-cell support for metastatic breast cancer: no improvement in progression-free survival by the sequence of high-dose melphalan followed by cyclophosphamide, thiotepa, and carboplatin by Ayash, L J, Elias, A, Schwartz, G, Wheeler, C, Ibrahim, J, Teicher, B A, Reich, E, Warren, D, Lynch, C, Richardson, P, Schnipper, L, Frei, 3rd, E, Antman, K

“…Twenty-one percent of responding metastatic breast cancer patients remain progression-free a median 50 months following one intensification cycle of…”
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Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents by Teicher, B A, Holden, S A, Ara, G, Sotomayor, E A, Huang, Z D, Chen, Y N, Brem, H

“…The ability of TNP-470, a synthetic analog of fumagillin which has been described as an anti-angiogenic agent, to potentiate cytotoxic cancer therapies was…”
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Transforming growth factor-beta and response to anticancer therapies in human liver and gastric tumors in vitro and in vivo by Liu, P, Menon, K, Alvarez, E, Lu, K, Teicher, B A

“…Liver cancer and gastric cancer are the most common solid tumors worldwide. Transforming growth factor-beta (TGF-beta) production and lack of response to…”
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Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma by TEICHER, B. A, HOLDEN, S. A, ARA, G, KORBUT, T, MENON, K

“…The efficacy of several potential antiangiogenic agents, TNP-470, minocycline, suramin, genistein, interferon delta 4, 14(sulfated)-beta-cyclodextrin and…”
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A carbonic anhydrase inhibitor as a potential modulator of cancer therapies by Teicher, B A, Liu, S D, Liu, J T, Holden, S A, Herman, T S

“…Since several anticancer drugs are known to become more cytotoxic to cells in an acidic milieu, we have attempted to utilize the carbonic anhydrase inhibitor,…”
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Oxymetry Deep in Tissues With Low-Frequency Electron Paramagnetic Resonance by Halpern, Howard J., Yu, Cheng, Peric, Miroslav, Barth, Eugene, Grdina, David J., Teicher, Beverly A.

“…We have measured the oxygen concentration in the body water of murine FSa and NFSa fibrosarcomas using a new method for quantitative oxygen concentration…”
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Antitumor activity of cryptophycins: effect of infusion time and combination studies by MENON, K, ALVAREZ, E, FORLER, P, PHARES, V, AMSRUD, T, SHIH, C, AL-AWAR, R, TEICHER, B. A

“…Cryptophycins are a family of antitubulin antitumor agents. A synthetic cryptophycin derivative (LY355703, CRYPTO 52) is in early clinical evaluation. The…”
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Overexpression of Metallothionein Confers Resistance to Anticancer Drugs by Kelley, Susan L., Basu, Alakananda, Teicher, Beverly A., Hacker, Miles P., Hamer, Dean H., Lazo, John S.

“…Resistance to antineoplastic agents is the major obstacle to curative therapy of cancer. Tumor cell lines with acquired resistance to the antineoplastic agent…”
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Diminished aqueous microviscosity of tumors in murine models measured with in vivo radiofrequency electron paramagnetic resonance by HALPERN, H. J, CHANDRAMOULI, G. V. R, BARTH, E. D, CHENG YU, PERIC, M, GRDINA, D. J, TEICHER, B. A

“…Using very low frequency in vivo electron paramagnetic resonance (EPR), we have compared, for the first time, the average microviscosity of the total aqueous…”
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Optimal scheduling of interleukin 12 and chemotherapy in the murine MB-49 bladder carcinoma and B16 melanoma by TEICHER, B. A, ARA, G, BUXTON, D, LEONARD, J, SCHAUB, R. G

“…The antitumor activity of interleukin (IL)-12, a naturally occurring cytokine, has been demonstrated in several murine solid tumors. Animals bearing…”
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Influence of an anti-angiogenic treatment on 9L gliosarcoma: oxygenation and response to cytotoxic therapy by Teicher, B A, Holden, S A, Ara, G, Dupuis, N P, Liu, F, Yuan, J, Ikebe, M, Kakeji, Y

“…Tissue oxygen tensions were measured in subcutaneously growing rat 9L gliosarcoma under normal air and carbogen breathing conditions prior to and after i.v…”
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