Search Results - "TEERLINK, J. R"

Disconnect between the effects of serelaxin on renal function and outcome in acute heart failure by Beldhuis, I. E., ter Maaten, J. M., Figarska, S. M., Damman, K., Pang, P. S., Greenberg, B., Davison, B. A., Cotter, G., Severin, T., Gimpelewicz, C., Felker, G. M., Filippatos, G., Teerlink, J. R., Metra, M., Voors, A. A.

“…Background We aimed to study whether improvement in renal function by serelaxin in patients who were hospitalized for acute heart failure (HF) might explain…”
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Effect of Nesiritide in Patients with Acute Decompensated Heart Failure by O'Connor, C.M, Starling, R.C, Hernandez, A.F, Armstrong, P.W, Dickstein, K, Hasselblad, V, Heizer, G.M, Komajda, M, Massie, B.M, McMurray, J.J.V, Nieminen, M.S, Reist, C.J, Rouleau, J.L, Swedberg, K, Adams, K.F, Anker, S.D, Atar, D, Battler, A, Botero, R, Bohidar, N.R, Butler, J, Clausell, N, Corbalán, R, Costanzo, M.R, Dahlstrom, U, Deckelbaum, L.I, Diaz, R, Dunlap, M.E, Ezekowitz, J.A, Feldman, D, Felker, G.M, Fonarow, G.C, Gennevois, D, Gottlieb, S.S, Hill, J.A, Hollander, J.E, Howlett, J.G, Hudson, M.P, Kociol, R.D, Krum, H, Laucevicius, A, Levy, W.C, Méndez, G.F, Metra, M, Mittal, S, Oh, B.-H, Pereira, N.L, Ponikowski, P, Tang, W.H.W, Tanomsup, S, Teerlink, J.R, Triposkiadis, F, Troughton, R.W, Voors, A.A, Whellan, D.J, Zannad, F, Califf, R.M

“…Nesiritide was approved by the FDA on the basis of small clinical trials for the treatment of acute heart failure. In this large clinical trial, nesiritide did…”
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Diuretic response in acute heart failure: clinical characteristics and prognostic significance by Valente, Mattia A. E., Voors, Adriaan A., Damman, Kevin, Van Veldhuisen, Dirk J., Massie, Barrie M., O'Connor, Christopher M., Metra, Marco, Ponikowski, Piotr, Teerlink, John R., Cotter, Gad, Davison, Beth, Cleland, John G.F., Givertz, Michael M., Bloomfield, Daniel M., Fiuzat, Mona, Dittrich, Howard C., Hillege, Hans L.

“…Aim Diminished diuretic response is common in patients with acute heart failure, although a clinically useful definition is lacking. Our aim was to investigate…”
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Potent Vasoconstriction Mediated by Endothelin ETB Receptors in Canine Coronary Arteries by Teerlink, John R, Breu, Volker, Sprecher, Urs, Clozel, Martine, Clozel, Jean-Paul

“…Endothelin (ET) 1 is a powerful vasoconstrictor of coronary arteries and may playa role in coronary spasm, atherosclerosis, and myocardial infarction. Previous…”
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Progressive Ventricular Remodeling in Response to Diffuse Isoproterenol-Induced Myocardial Necrosis in Rats by Teerlink, John R, Pfeffer, Janice M, Pfeffer, Marc A

“…The purpose of the present study was to gain a better understanding of the relation between ventricular remodeling and heart failure by assessing the…”
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Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure : acute effects of the endothelin receptor antagonist Ro 47-0203 (Bosentan) by TEERLINK, J. R, LÖFFLER, B.-M, HESS, P, MAIRE, J.-P, CLOZEL, M, CLOZEL, J.-P

“…Endothelin (ET) is a potent vasoconstrictor, and its concentration is increased in patients with heart failure. The purpose of this study was to investigate…”
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Effects of tolvaptan on dyspnoea relief from the EVEREST trials by Pang, Peter S., Konstam, Marvin A., Krasa, Holly B., Swedberg, Karl, Zannad, Faiez, Blair, John E.A., Zimmer, Christopher, Teerlink, John R., Maggioni, Aldo P., Burnett, John C., Grinfeld, Liliana, Ouyang, John, Udelson, James E., Gheorghiade, Mihai

“…Aims To describe the effects of tolvaptan therapy on dyspnoea relief based on timing of delivery, influence of concomitant therapies, and baseline patient and…”
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Role of endogenous endothelin in normal hemodynamic status of anesthetized dogs by Teerlink, J R, Carteaux, J P, Sprecher, U, Löffler, B M, Clozel, M, Clozel, J P

“…Endothelin (ET) is a potent vasoconstrictor that may be involved in a number of cardiovascular disorders, although its role in normal hemodynamics remains…”
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Hemodynamic variability and circadian rhythm in rats with heart failure: role of locomotor activity by Teerlink, J R, Clozel, J P

“…Heart rate variability is known to be decreased by heart failure; however, the influences of concomitant diseases, changes in activity level, evolution through…”
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Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent : dissociation of basal and stimulated nitric oxide release by TEERLINK, J. R, GRAY, G. A, CLOZEL, M, CLOZEL, J.-P

“…Endothelial dysfunction and abnormal vascular responsiveness to vasoconstrictors may play an important role in chronic heart failure (CHF). The purpose of our…”
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The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial by Voors, Adriaan A., Angermann, Christiane E., Teerlink, John R., Collins, Sean P., Kosiborod, Mikhail, Biegus, Jan, Ferreira, João Pedro, Nassif, Michael E., Psotka, Mitchell A., Tromp, Jasper, Borleffs, C. Jan Willem, Ma, Changsheng, Comin-Colet, Joseph, Fu, Michael, Janssens, Stefan P., Kiss, Robert G., Mentz, Robert J., Sakata, Yasushi, Schirmer, Henrik, Schou, Morten, Schulze, P. Christian, Spinarova, Lenka, Volterrani, Maurizio, Wranicz, Jerzy K., Zeymer, Uwe, Zieroth, Shelley, Brueckmann, Martina, Blatchford, Jonathan P., Salsali, Afshin, Ponikowski, Piotr

“…The sodium–glucose cotransporter 2 inhibitor empagliflozin reduces the risk of cardiovascular death or heart failure hospitalization in patients with chronic…”
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Cardiac inotropes: current agents and future directions by Hasenfuss, Gerd, Teerlink, John R.

“…Intrinsic inotropic stimulation of the heart is central to the regulation of cardiovascular function, and exogenous inotropic therapies have been used…”
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Cardiac Calcitropes, Myotropes, and Mitotropes: JACC Review Topic of the Week by Psotka, Mitchell A, Gottlieb, Stephen S, Francis, Gary S, Allen, Larry A, Teerlink, John R, Adams, Jr, Kirkwood F, Rosano, Giuseppe M C, Lancellotti, Patrizio

“…The term "inotrope" is familiar and intimately connected with pharmaceuticals clinically used for treatment of low cardiac output with cardiogenic shock…”
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Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial by Vardeny, Orly, Claggett, Brian, Packer, Milton, Zile, Michael R., Rouleau, Jean, Swedberg, Karl, Teerlink, John R., Desai, Akshay S., Lefkowitz, Martin, Shi, Victor, McMurray, John J.V., Solomon, Scott D.

“…Aims In this analysis, we utilized data from PARADIGM‐HF to test the hypothesis that participants who exhibited any dose reduction during the trial would have…”
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The interaction of ACE inhibitors and aspirin in heart failure: Torn between two lovers by Teerlink, John R., Massie, Barry M.

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The role of beta-blockers in preventing sudden death in heart failure by Teerlink, J R, Massie, B M

“…Sudden death accounts for one third to one half of the deaths in patients with heart failure. Recent studies using beta-adrenergic blockers in patients with…”
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Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure by Packer, Milton, McMurray, John J V, Desai, Akshay S, Gong, Jianjian, Lefkowitz, Martin P, Rizkala, Adel R, Rouleau, Jean L, Shi, Victor C, Solomon, Scott D, Swedberg, Karl, Zile, Michael, Andersen, Karl, Arango, Juan Luis, Arnold, J Malcolm, Bělohlávek, Jan, Böhm, Michael, Boytsov, Sergey, Burgess, Lesley J, Cabrera, Walter, Calvo, Carlos, Chen, Chen-Huan, Dukat, Andrej, Duarte, Yan Carlos, Erglis, Andrejs, Fu, Michael, Gomez, Efrain, Gonzàlez-Medina, Angel, Hagège, Albert A, Huang, Jun, Katova, Tzvetana, Kiatchoosakun, Songsak, Kim, Kee-Sik, Kozan, Ömer, Llamas, Edmundo Bayram, Martinez, Felipe, Merkely, Bela, Mendoza, Iván, Mosterd, Arend, Negrusz-Kawecka, Marta, Peuhkurinen, Keijo, Ramires, Felix J A, Refsgaard, Jens, Rosenthal, Arvo, Senni, Michele, Sibulo, Jr, Antonio S, Silva-Cardoso, José, Squire, Iain B, Starling, Randall C, Teerlink, John R, Vanhaecke, Johan, Vinereanu, Dragos, Wong, Raymond Ching-Chiew

“…Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known…”
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Valvular heart disease in pregnancy. A contemporary perspective by Teerlink, J R, Foster, E

“…Valvular heart disease may have a significant impact on the course and outcome of pregnancy with implications for fetal as well as maternal health. Optimally,…”
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Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study by Teerlink, John R, Prof, Metra, Marco, Prof, Felker, G Michael, MD, Ponikowski, Piotr, Prof, Voors, Adriaan A, MD, Weatherley, Beth Davison, PhD, Marmor, Alon, Prof, Katz, Amos, Prof, Grzybowski, Jacek, MD, Unemori, Elaine, PhD, Teichman, Sam L, MD, Cotter, Gad, MD

“…Summary Background Most patients admitted for acute heart failure have normal or increase blood pressure. Relaxin is a natural human peptide that affects…”
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Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial by Filippatos, Gerasimos, Teerlink, John R., Farmakis, Dimitrios, Cotter, Gad, Davison, Beth A., Felker, G. Michael, Greenberg, Barry H., Hua, Tsushung, Ponikowski, Piotr, Severin, Thomas, Unemori, Elaine, Voors, Adriaan A., Metra, Marco

“…Aims Serelaxin is effective in relieving dyspnoea and improving multiple outcomes in acute heart failure (AHF). Many AHF patients have preserved ejection…”
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