Search Results - "TEDDER, R."

Hepatitis E: the current state of play by Ankcorn, M. J., Tedder, R. S.

“…SUMMARY The hepatitis E virus (HEV) is a major cause of acute hepatitis globally. Genotypes 1 and 2 (G1 and G2) are obligate human pathogens transmitted…”
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The epidemiology of hepatitis B virus infection in HIV-infected and HIV-uninfected pregnant women in the Western Cape, South Africa by Andersson, M.I, Maponga, T.G, Ijaz, S, Barnes, J, Theron, G.B, Meredith, S.A, Preiser, W, Tedder, R.S

“…Highlights • HIV-infected pregnant women have evidence of HBV escape compared to uninfected women. • One in six HBV-infected pregnant women is HBeAg…”
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Hepatitis E virus in England and Wales: indigenous infection is associated with the consumption of processed pork products by SAID, B., IJAZ, S., CHAND, M. A., KAFATOS, G., TEDDER, R., MORGAN, D.

“…Indigenously acquired hepatitis E infections have increased substantially in England and Wales since 2010. Epidemiological investigations were undertaken to…”
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Pork products associated with human infection caused by an emerging phylotype of hepatitis E virus in England and Wales by SAID, B., USDIN, M., WARBURTON, F., IJAZ, S., TEDDER, R.S., MORGAN, D.

“…Since 2010, human hepatitis E infections have increased in England and Wales. Most cases are locally acquired and caused by hepatitis E virus genotype 3 (HEV…”
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Detection of hepatitis E virus RNA in plasma mini-pools from blood donors in England by Ijaz, S., Szypulska, R., Tettmar, K. I., Kitchen, A., Tedder, R. S.

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Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors? by Beale, M. A., Tettmar, K., Szypulska, R., Tedder, R. S., Ijaz, S.

“…Background and Objective  The risk of hepatitis E virus (HEV) to blood safety remains unknown in England. Reports of persistent HEV infection with serious…”
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Ebola virus antibody decay–stimulation in a high proportion of survivors by Adaken, Charlene, Scott, Janet T., Sharma, Raman, Gopal, Robin, Dicks, Steven, Niazi, Saidia, Ijaz, Samreen, Edwards, Tansy, Smith, Catherine C., Cole, Christine P., Kamara, Philip, Kargbo, Osman, Doughty, Heidi A., van Griensven, Johan, Horby, Peter W., Gevao, Sahr M., Sahr, Foday, Dimelow, Richard J., Tedder, Richard S., Semple, Malcolm G., Paxton, William A., Pollakis, Georgios

“…Neutralizing antibody function provides a foundation for the efficacy of vaccines and therapies 1 – 3 . Here, using a robust in vitro Ebola virus (EBOV)…”
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The incubation period of hepatitis E genotype 1: insights from pooled analyses of travellers by Azman, A S, Ciglenecki, I, Oeser, C, Said, B, Tedder, R S, Ijaz, S

“…Hepatitis E virus genotype 1 (HEV G1) is an important cause of morbidity and mortality in Africa and Asia. HEV G1's natural history, including the incubation…”
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Racial differences in seroprevalence of HAV and HEV in blood donors in the Western Cape, South Africa: a clue to the predominant HEV genotype? by LOPES, T., CABLE, R., PISTORIUS, C., MAPONGA, T., IJAZ, S., PREISER, W., TEDDER, R., ANDERSSON, M. I.

“…Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. This infection causes major water-borne outbreaks in low- and middle-income…”
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Therapy-induced clearance of HCV core antigen from plasma predicts an end of treatment viral response by Tedder, R. S., Tuke, P., Wallis, N., Wright, M., Nicholson, L., Grant, P. R.

“…During viral assembly, viral proteins are released into plasma and can be used to infer viral load. The Architect hepatitis C virus (HCV) core antigen (Ag)…”
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Using data linkage to improve surveillance methods for acute hepatitis E infections in England and Wales 2010–2016 by OESER, C., SAID, B., WARBURTON, F., IJAZ, S., TEDDER, R., MORGAN, D.

“…Indigenous, foodborne transmission of hepatitis E has been increasing across industrialised countries. Public Health England has conducted enhanced…”
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Confirmation of specificity of reactivity in a solid phase ELISA for the detection of hepatitis E viral antigen improves utility of the assay by Ankcorn, M.J., Ijaz, S., Haywood, B., Neuberger, J., Elsharkawy, A.M., Maggs, J., Tedder, R.S.

“…•We developed a novel neutralisation step for a commercial HEV antigen assay.•Neutralisation identifies non-specific reactivity in plasma and non-plasma…”
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Real-time PCR quantitation of hepatitis B virus DNA using automated sample preparation and murine cytomegalovirus internal control by Garson, J.A., Grant, P.R., Ayliffe, U., Ferns, R.B., Tedder, R.S.

“…Quantitation of circulating hepatitis B virus (HBV) DNA is important for monitoring disease progression and for assessing the response to antiviral therapy…”
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Hepatitis B surface antigen expression: A pilot study comparing wild type and surface antigen mutant viruses by Jeffery-Smith, A, Poh, J, Ijaz, S, Tedder, R

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Outbreak of hepatitis A in an extended family after importation by non-immune travellers by KUMBANG, J., EJIDE, S., TEDDER, R. S., NGUI, S. L.

“…The incidence of hepatitis A in England has declined in recent years, but travel-related cases and imported infections remain a challenge. We report an…”
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Indigenous Hepatitis E in England and Wales From 2003 to 2012: Evidence of an Emerging Novel Phylotype of Viruses by Ijaz, Samreen, Said, Bengü, Boxall, Elizabeth, Smit, Erasmus, Morgan, Dilys, Tedder, Richard S.

“…Background. Enhanced surveillance and molecular characterisation studies of hepatitis E virus (HEV) in England and Wales have been undertaken since 2003. The…”
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Understanding immunisation failure of neonatal HBV prevention by May, Shoshanna, Mendal, Sema, Ngui, Siew Lin, Ramsay, M, Tedder, R, Samreen, I

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Use of genome sequencing to identify hepatitis C virus transmission in a renal healthcare setting by Garvey, Mark I, Bradley, Craig W, Holden, Kerry, Hewins, Peter, Ngui, Siew-Lin, Tedder, Richard, Jumaa, Pauline, Smit, Erasmus

“…Summary Hepatitis C virus (HCV) infection is a major health burden worldwide. A patient with no history of HCV infection while on a renal unit was found to…”
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Detection of bacterial contamination in platelet concentrates from Brazilian donors by molecular amplification of the ribosomal 16S gene by Viana, J. D., Ferreira, S. C., Matana, S. R., Rossi, F., Patel, P., Garson, J. A., Rocha, V., Tedder, R., Mendrone‐Júnior, A., Levi, J. E.

“…Summary Objective The aim of our work was to establish a semi‐automated high‐throughput DNA amplification method for the universal screening of bacteria in…”
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Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma by Whitby, D, Howard, M R, Tenant-Flowers, M, Brink, N S, Copas, A, Boshoff, C, Hatzioannou, T, Suggett, F E, Aldam, D M, Denton, A S

“…Kaposi sarcoma-associated herpesvirus (KSHV) is consistently found in biopsy samples from patients with AIDS-related and "classical" Kaposi's sarcoma (KS)…”
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