Search Results - "TCHERNOF, Andre"
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Pathophysiology of human visceral obesity: an update
Published in Physiological reviews (01-01-2013)“…Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of a phenotype including dysfunctional subcutaneous adipose tissue…”
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Obesity Phenotypes, Diabetes, and Cardiovascular Diseases
Published in Circulation research (22-05-2020)“…This review addresses the interplay between obesity, type 2 diabetes mellitus, and cardiovascular diseases. It is proposed that obesity, generally defined by…”
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A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study
Published in The American journal of clinical nutrition (01-08-2016)“…To date, most studies on the anti-inflammatory effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in humans have used a mixture of the 2…”
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Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction
Published in Critical reviews in clinical laboratory sciences (01-01-2015)“…Obesity is a heterogeneous disease and is associated with comorbidities such as type 2 diabetes mellitus, cardiovascular disease and cancer. Several studies…”
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Adiposity, breast density, and breast cancer risk: epidemiological and biological considerations
Published in European journal of cancer prevention (01-11-2017)“…Excess total body fat and abdominal adipose tissue are recognized risk factors for metabolic diseases but also for some types of cancers, including breast…”
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Androgens and body fat distribution
Published in Journal of steroid biochemistry and molecular biology (01-02-2008)“…An important sex difference in body fat distribution is generally observed. Men are usually characterized by the android type of obesity, with accumulation of…”
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Glutamate and obesity - what is the link?
Published in Current opinion in clinical nutrition and metabolic care (01-01-2024)“…Many studies using metabolomics have tried to unravel the metabolic signature of obesity and understand the pathophysiology of this complex and heterogeneous…”
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Fat Cell Size: Measurement Methods, Pathophysiological Origins, and Relationships With Metabolic Dysregulations
Published in Endocrine reviews (01-02-2022)“…Abstract The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes, cardiovascular diseases and many other chronic diseases. Fat…”
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Metabolic adaptations after bariatric surgery: adipokines, myokines and hepatokines
Published in Current opinion in pharmacology (01-06-2020)“…This review addresses the impact of bariatric surgery on the endocrine aspects of white adipose tissue, muscle and the liver. We describe literature supporting…”
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Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types
Published in Nature metabolism (01-01-2020)“…The complex relationship between metabolic disease risk and body fat distribution in humans involves cellular characteristics that are specific to body fat…”
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Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk
Published in American journal of physiology: endocrinology and metabolism (15-10-2015)“…Metabolomic profiling of obese individuals revealed altered concentrations of many metabolites, especially branched-chain amino acids (BCAA), possibly linked…”
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Management of Obesity in Cardiovascular Practice: JACC Focus Seminar
Published in Journal of the American College of Cardiology (03-08-2021)“…Obesity contributes to reduced life expectancy because of its link with type 2 diabetes and cardiovascular disease. Yet, targeting this poorly diagnosed,…”
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Impact of weight loss on brain age: Improved brain health following bariatric surgery
Published in NeuroImage (Orlando, Fla.) (01-10-2022)“…Individuals living with obesity tend to have increased brain age, reflecting poorer brain health likely due to grey and white matter atrophy related to…”
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Spontaneous neural activity changes after bariatric surgery: A resting-state fMRI study
Published in NeuroImage (Orlando, Fla.) (01-11-2021)“…Metabolic disorders associated with obesity could lead to alterations in brain structure and function. Whether these changes can be reversed after weight loss…”
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Ethnic Variation in Fat and Lean Body Mass and the Association with Insulin Resistance
Published in The journal of clinical endocrinology and metabolism (01-12-2009)“…Context: Body fat distribution varies among different ethnic groups, yet less is known regarding differences in lean mass and how this may affect insulin…”
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Bariatric Surgery Should Be Offered to Active-Duty Military Personnel: a Retrospective Study of the Canadian Armed Forces’ Experience
Published in Obesity surgery (01-04-2023)“…Purpose Like most Western armies, obesity affects Canadian Armed Forces (CAF) personnel. Bariatric surgery is an effective treatment for obesity. However, this…”
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Associations between markers of mammary adipose tissue dysfunction and breast cancer prognostic factors
Published in International Journal of Obesity (01-01-2021)“…Background Obesity fosters worse clinical outcomes in both premenopausal and postmenopausal women with breast cancer. Emerging evidence suggests that an…”
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Visceral Adipocyte Hypertrophy is Associated With Dyslipidemia Independent of Body Composition and Fat Distribution in Women
Published in Diabetes (New York, N.Y.) (01-05-2011)“…We assessed whether subcutaneous and omental adipocyte hypertrophy are related to metabolic alterations independent of body composition and fat distribution in…”
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Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk
Published in Nutrition, metabolism, and cardiovascular diseases (01-12-2019)“…Circulating level of glutamate, a by-product of the catabolism of branched-chain amino acids, has been positively correlated with visceral adipose tissue…”
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Increased body fat mass explains the positive association between circulating estradiol and insulin resistance in postmenopausal women
Published in American journal of physiology: endocrinology and metabolism (01-05-2018)“…The relationship between circulating estrogen levels and cardiometabolic risk factors such as insulin resistance is unclear in postmenopausal women. High…”
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