Search Results - "TAYLOR, Fletcher"

Extracellular histones are major mediators of death in sepsis by Esmon, Charles T, Xu, Jun, Zhang, Xiaomei, Pelayo, Rosana, Monestier, Marc, Ammollo, Concetta T, Semeraro, Fabrizio, Taylor, Fletcher B, Esmon, Naomi L, Lupu, Florea

“…Extracellular histones released in response to inflammatory challenge contribute to organ failure and death during sepsis. Histone-specific antibodies and…”
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The effects of stress exposure on prefrontal cortex: Translating basic research into successful treatments for post-traumatic stress disorder by Arnsten, Amy F.T., Raskind, Murray A., Taylor, Fletcher B., Connor, Daniel F.

“…Research on the neurobiology of the stress response in animals has led to successful new treatments for Post-Traumatic Stress Disorder (PTSD) in humans. Basic…”
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In vivo–generated thrombin and plasmin do not activate the complement system in baboons by Keshari, Ravi S., Silasi, Robert, Lupu, Cristina, Taylor, Fletcher B., Lupu, Florea

“…Sepsis concurrently activates both coagulation and complement systems. Although complement activation by bacteria is well documented, work in mice and in vitro…”
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Sphingosine 1‐phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons by Frej, Cecilia, Linder, Adam, Happonen, Kaisa E., Taylor, Fletcher B., Lupu, Florea, Dahlbäck, Björn

“…Sphingosine 1‐phosphate (S1P) is an important regulator of vascular integrity and immune cell migration, carried in plasma by high‐density lipoprotein…”
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Prazosin Effects on Objective Sleep Measures and Clinical Symptoms in Civilian Trauma Posttraumatic Stress Disorder: A Placebo-Controlled Study by Taylor, Fletcher B, Martin, Patti, Thompson, Charles, Williams, Judi, Mellman, Thomas A, Gross, Christopher, Peskind, Elaine R, Raskind, Murray A

“…Background Prazosin, a central nervous system (CNS) active α-1 adrenoreceptor antagonist, has reduced nightmares and sleep disturbance in placebo-controlled…”
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Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis by Silasi-Mansat, Robert, Zhu, Hua, Popescu, Narcis I., Peer, Glenn, Sfyroera, Georgia, Magotti, Paola, Ivanciu, Lacramioara, Lupu, Cristina, Mollnes, Tom E., Taylor, Fletcher B., Kinasewitz, Gary, Lambris, John D., Lupu, Florea

“…Severe sepsis leads to massive activation of coagulation and complement cascades that could contribute to multiple organ failure and death. To investigate the…”
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A local general‐equilibrium emergency response modeling approach for sub‐Saharan Africa by Filipski, Mateusz, Gupta, Anubhab, Kagin, Justin, Husain, Arif, Grinspun, Alejandro, Caccavale, Oscar Maria, Daidone, Silvio, Giuffrida, Valerio, Greb, Friederike, Hooker, Joseph, Sandström, Susanna, Fletcher‐Taylor, Julian, Taylor, J. Edward

“…Swift response models are vital tools for emergency assistance agencies. The COVID‐19 pandemic revealed the lack of economic models for short‐run policy…”
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Sepsis and Pathophysiology of Anthrax in a Nonhuman Primate Model by Stearns-Kurosawa, Deborah J., Lupu, Florea, Taylor, Fletcher B., Kinasewitz, Gary, Kurosawa, Shinichiro

“…Studies that define natural responses to bacterial sepsis assumed new relevance after the lethal bioterrorist attacks with Bacillus anthracis (anthrax), a…”
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Tissue Factor-Dependent Coagulation Is Preferentially Up-Regulated within Arterial Branching Areas in a Baboon Model of Escherichia coli Sepsis by Lupu, Cristina, Westmuckett, Andrew D., Peer, Glenn, Ivanciu, Lacramioara, Zhu, Hua, Taylor, Fletcher B., Lupu, Florea

“…Endothelium plays a critical role in the pathobiology of sepsis by integrating systemic host responses and local rheological stimuli. We studied the…”
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Pathophysiology, staging and therapy of severe sepsis in baboon models by Taylor, Fletcher B., Kinasewitz, Gary T, Lupu, Florea

“…•  Introduction •  Modeling the shock/disseminated intravascular coagulation (DIC) variant of severe sepsis using the LD100 baboon model of E. coli sepsis   ‐…”
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Sepsis-Induced Coagulation in the Baboon Lung Is Associated with Decreased Tissue Factor Pathway Inhibitor by Tang, Haiwang, Ivanciu, Lacramioara, Popescu, Narcis, Peer, Glenn, Hack, Erik, Lupu, Cristina, Taylor, Fletcher B, Lupu, Florea

“…Increased tissue factor (TF)-dependent procoagulant activity in sepsis may be partly due to decreased expression or function of tissue factor pathway inhibitor…”
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Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon by Binette, Tanya M., Taylor, Fletcher B., Peer, Glenn, Bajzar, Laszlo

“…Thrombin activatable fibrinolysis inhibitor (TAFI), when activated, forms a basic carboxypeptidase that can inhibit fibrinolysis. Potential physiologic…”
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Complement inhibition decreases early fibrogenic events in the lung of septic baboons by Silasi‐Mansat, Robert, Zhu, Hua, Georgescu, Constantin, Popescu, Narcis, Keshari, Ravi S., Peer, Glenn, Lupu, Cristina, Taylor, Fletcher B., Pereira, Heloise Anne, Kinasewitz, Gary, Lambris, John D., Lupu, Florea

“…Acute respiratory distress syndrome (ARDS) induced by severe sepsis can trigger persistent inflammation and fibrosis. We have shown that experimental sepsis in…”
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Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells by Tilley, Drew C, Eum, Kenneth S, Fletcher-Taylor, Sebastian, Austin, Daniel C, Dupré, Christophe, Patrón, Lilian A, Garcia, Rita L, Lam, Kit, Yarov-Yarovoy, Vladimir, Cohen, Bruce E, Sack, Jon T

“…Significance Electrically excitable cells, such as neurons, exhibit tremendous variation in their patterns of electrical signals. These variations arise from…”
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Practitioners of open dialogue report their personal transformations as a result of conducting network meetings by Taylor, Alita Kathryn, Taylor, Fletcher Brandon, Anderson, Deborah Ann

“…As health care providers practicing Open Dialogue, we cleave to the notion that the support we provide to users and their communities will lead to the kind of…”
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Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis by Zhu, Hua, Tang, Yuhong, Ivanciu, Lacramioara, Centola, Michael, Lupu, Cristina, Taylor, Jr, Fletcher B, Lupu, Florea

“…Bacterial invasion during sepsis induces disregulated systemic responses that could lead to fatal lung failure. The purpose of this study was to relate the…”
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Endothelial cell protein C receptor plays an important role in protein C activation in vivo by Taylor, Fletcher B., Peer, Glenn T., Lockhart, Marion S., Ferrell, Gary, Esmon, Charles T.

“…Endothelial cell protein C receptor (EPCR) augments protein C activation by the thrombin-thrombomodulin complex about 5-fold in vitro. Augmentation is EPCR…”
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Tiagabine for posttraumatic stress disorder : A case series of 7 women by TAYLOR, Fletcher B

“…Posttraumatic stress disorder (PTSD) is often a chronic disorder, and, though 2 antidepressants are now approved by the U.S. Food and Drug Administration for…”
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Daytime Prazosin Reduces Psychological Distress to Trauma Specific Cues in Civilian Trauma Posttraumatic Stress Disorder by Taylor, Fletcher B., Lowe, Kathleen, Thompson, Charles, McFall, Miles M., Peskind, Elaine R., Kanter, Evan D., Allison, Nancy, Williams, Judi, Martin, Patti, Raskind, Murray A.

“…Persons with posttraumatic stress disorder (PTSD) whose trauma-related nightmares improve or resolve with bedtime administration of the alpha-1 adrenergic…”
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Comparing guanfacine and dextroamphetamine for the treatment of Adult attention-deficit/hyperactivity disorder by TAYLOR, Fletcher B, RUSSO, Joan

“…The objective of this study was to compare the efficacy of the alpha-2a agonist guanfacine with that of dextroamphetamine for the treatment of adult…”
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