Search Results - "TAYLOR, E. B."

High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis by Janesick, Amanda, Shelansky, Robert, Gottscho, Andrew D., Wagner, Florian, Williams, Stephen R., Rouault, Morgane, Beliakoff, Ghezal, Morrison, Carolyn A., Oliveira, Michelli F., Sicherman, Jordan T., Kohlway, Andrew, Abousoud, Jawad, Drennon, Tingsheng Yu, Mohabbat, Seayar H., Taylor, Sarah E. B.

“…Single-cell and spatial technologies that profile gene expression across a whole tissue are revolutionizing the resolution of molecular states in clinical…”
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Extent and scale of local adaptation in salmonid fishes: review and meta-analysis by Fraser, D J, Weir, L K, Bernatchez, L, Hansen, M M, Taylor, E B

“…What is the extent and scale of local adaptation (LA)? How quickly does LA arise? And what is its underlying molecular basis? Our review and meta-analysis on…”
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Speciation in reverse: morphological and genetic evidence of the collapse of a three-spined stickleback (Gasterosteus aculeatus) species pair by TAYLOR, E. B., BOUGHMAN, J. W., GROENENBOOM, M., SNIATYNSKI, M., SCHLUTER, D., GOW, J. L.

“…Historically, six small lakes in southwestern British Columbia each contained a sympatric species pair of three‐spined sticklebacks (Gasterosteus aculeatus)…”
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Stable 5‐Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation by Taylor, Sarah EB, Li, Ye Henry, Smeriglio, Piera, Rath, Madhusikta, Wong, Wing H, Bhutani, Nidhi

“…ABSTRACT Regulation of gene expression changes during chondrogenic differentiation by DNA methylation and demethylation is little understood. Methylated…”
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Genome‐Wide Mapping of DNA Hydroxymethylation in Osteoarthritic Chondrocytes by Taylor, Sarah E. B., Li, Ye Henry, Wong, Wing H., Bhutani, Nidhi

“…Objective To examine the genome‐wide distribution of hydroxymethylated cytosine (5hmC) in osteoarthritic (OA) and normal chondrocytes in order to investigate…”
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Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cells by Lee, Jieun, Taylor, Sarah E. B., Smeriglio, Piera, Lai, Janice, Maloney, William J., Yang, Fan, Bhutani, Nidhi

“…Regeneration of human cartilage is inherently inefficient; an abundant autologous source, such as human induced pluripotent stem cells (hiPSCs), is therefore…”
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Hepatitis B vaccination uptake in hard-to-reach populations in London: a cross-sectional study by Taylor, Josephine E B, Surey, Julian, MacLellan, Jennifer, Francis, Marie, Abubakar, Ibrahim, Stagg, Helen R

“…In the UK, hepatitis B virus (HBV) incidence is associated with migrants from particular high-burden countries and population groups deemed 'hard-to-reach' by…”
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Spatial transcriptomics at subspot resolution with BayesSpace by Zhao, Edward, Stone, Matthew R., Ren, Xing, Guenthoer, Jamie, Smythe, Kimberly S., Pulliam, Thomas, Williams, Stephen R., Uytingco, Cedric R., Taylor, Sarah E. B., Nghiem, Paul, Bielas, Jason H., Gottardo, Raphael

“…Recent spatial gene expression technologies enable comprehensive measurement of transcriptomic profiles while retaining spatial context. However, existing…”
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Replicate divergence between and within sounds in a marine fish: the copper rockfish (Sebastes caurinus) by Dick, S, Shurin, J. B, Taylor, E. B

“…Understanding the factors that influence larval dispersal and connectivity among marine populations is critical to the conservation and sustainable management…”
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Coexistence and origin of trophic ecotypes of pygmy whitefish, Prosopium coulterii, in a south‐western Alaskan lake by Gowell, C. P., Quinn, T. P., Taylor, E. B.

“…Ecologically, morphologically and genetically distinct populations within single taxa often coexist in postglacial lakes and have provided important model…”
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Ecological selection against hybrids in natural populations of sympatric threespine sticklebacks by GOW, J. L., PEICHEL, C. L., TAYLOR, E. B.

“…Experimental work has provided evidence for extrinsic post‐zygotic isolation, a phenomenon unique to ecological speciation. The role that ecological components…”
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Geochemical evidence for deep mantle melting and lithospheric delamination as the origin of the inland Damavand volcanic rocks of northern Iran by Mirnejad, H., Hassanzadeh, J., Cousens, B.L., Taylor, B.E.

“…The intraplate Damavand volcanic field that overlies the Alborz Mountains in northern Iran is dominantly comprised of trachyandesite and alkali olivine basalt…”
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THE INFLUENCE OF HISTORY AND CONTEMPORARY STREAM HYDROLOGY ON THE EVOLUTION OF GENETIC DIVERSITY WITHIN SPECIES: AN EXAMINATION OF MICROSATELLITE DNA VARIATION IN BULL TROUT, SALVELINUS CONFLUENTUS (PISCES: SALMONIDAE) by Costello, A. B, Down, T. E, Pollard, S. M, Pacas, C. J, Taylor, E. B

“…An understanding of the relative roles of historical and contemporary factors in structuring genetic variation is a fundamental, but understudied aspect of…”
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The origins of ecotypic variation of rainbow trout: a test of environmental vs. genetically based differences in morphology by KEELEY, E. R., PARKINSON, E. A., TAYLOR, E. B.

“…Although morphological plasticity has been observed in a variety of taxa, few experimental studies have compared the relative proportion of morphological…”
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A Global Increase in 5‐Hydroxymethylcytosine Levels Marks Osteoarthritic Chondrocytes by Taylor, Sarah E. B., Smeriglio, Piera, Dhulipala, Lakshmi, Rath, Madhusikta, Bhutani, Nidhi

“…Objective To investigate the role of the newly discovered epigenetic mark 5‐hydroxymethylcytosine (5hmC) and its regulators in altered gene expression in…”
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POPULATION STRUCTURE IN THREE SPECIES OF CO‐DISTRIBUTED SALMONID FISHES IN THE PEACE RIVER AND TRIBUTARIES NEAR A MAJOR PROPOSED HYDROELECTRIC DEVELOPMENT IN NORTHEASTERN BRITISH COLUMBIA, CANADA by Taylor, E. B, Yau, M. M, Mattock, A. B

“…Dam construction and reservoir formation represent profound anthropogenic alterations to natural riverscapes, especially in terms of connectivity in migratory…”
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Coexistence of sperm-dependent asexuals and their sexual hosts: the role of differences in fitness-related traits by Mee, J. A., Chan, C., Taylor, E. B.

“…Understanding the mechanisms of coexistence of sperm-dependent asexuals and their sexual hosts requires an empirical evaluation of their relative fitness. We…”
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Evidence for bimodal hybrid zones between two species of char (Pisces: Salvelinus) in northwestern North America by Redenbach, Z., Taylor, E. B.

“…Dolly Varden (Salvelinus malma, Pisces: Salmonidae) and bull trout (Salvelinus confluentus) have widely overlapping, but largely parapatric ranges in…”
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Historical contingency and ecological determinism interact to prime speciation in sticklebacks, Gasterosteus by Taylor, Eric B., Donald McPhail, J.

“…) where determinism has been implicated as an important factor driving evolutionary novelty. Microsatellite DNA variation at six loci revealed relatively low…”
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Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25 by Taylor, E B, Ellingson, W J, Lamb, J D, Chesser, D G, Winder, W W

“…Activation of the AMP-activated protein kinase (AMPK) results in acute changes in cellular metabolism and transcriptional events that make the cell more robust…”
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