Search Results - "TAVANO, Regina"
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Opsonins and Dysopsonins of Nanoparticles: Facts, Concepts, and Methodological Guidelines
Published in Frontiers in immunology (12-10-2020)“…Understanding the effects mediated by a set of nanoparticle (NP)-bound host biomolecules, often indicated with the term of , is essential in nanomedicine,…”
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C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes
Published in ACS nano (26-06-2018)“…Poly(2-methyl-2-oxazoline) (PMOXA) is an alternative promising polymer to poly(ethylene glycol) (PEG) for design and engineering of macrophage-evading…”
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Poly(lipoic acid)-Based Nanoparticles as Self-Organized, Biocompatible, and Corona-Free Nanovectors
Published in Biomacromolecules (08-02-2021)“…Herein we present an innovative approach to produce biocompatible, degradable, and stealth polymeric nanoparticles based on poly(lipoic acid), stabilized by a…”
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Essential protocols for decoding the composition and the functional effects of the nanoparticle protein corona
Published in Frontiers in nanotechnology (23-10-2024)“…Identifying the function and composition of the protein corona (i.e., the set of host proteins interacting with nanoparticles) is considered a crucial step in…”
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Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic
Published in Antioxidants (09-06-2024)“…α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its…”
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Graphene Oxide Chemical Refining Screening to Improve Blood Compatibility of Graphene-Based Nanomaterials
Published in Journal of nanotheranostics (20-02-2024)“…Graphene oxide (GO) nanoparticles, due to their favorable water solubility, compared to graphene (GA), are a hot research topic in biomedical and…”
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Self-Assembled Biocompatible Fluorescent Nanoparticles for Bioimaging
Published in Frontiers in chemistry (28-03-2019)“…Fluorescence is a powerful tool for mapping biological events in real-time with high spatial resolution. Ultra-bright probes are needed in order to achieve…”
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Nanoparticles Based on Cross-Linked Poly(Lipoic Acid) Protect Macrophages and Cardiomyocytes from Oxidative Stress and Ischemia Reperfusion Injury
Published in Antioxidants (05-05-2022)“…The control of radical damage and oxidative stress, phenomena involved in a large number of human pathologies, is a major pharmaceutical and medical goal. We…”
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Stem-cell therapy in an experimental model of pulmonary hypertension and right heart failure: Role of paracrine and neurohormonal milieu in the remodeling process
Published in The Journal of heart and lung transplantation (01-11-2011)“…Background In this study we investigated the effect of human amniotic fluid stem (hAFS) cells and rat adipose tissue stromal vascular fraction GFP-positive…”
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The membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA– OMVs, without further stimulating their proinflammatory activity on circulating monocytes
Published in Journal of leukocyte biology (01-07-2009)“…Anti‐Meningococcus B vaccine candidate stimulates macrophages. Hypervirulent MenB causing fatal human infections frequently display the oligomeric‐coiled coil…”
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Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles
Published in Nanomedicine (London, England) (01-08-2010)“…Undesired alterations of the blood clotting balance may follow the intravascular injection of nanotherapeutics/diagnostics. Here, we tested the procoagulant…”
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The soluble recombinant Neisseria meningitidis adhesin NadA(Δ351-405) stimulates human monocytes by binding to extracellular Hsp90
Published in PloS one (2011)“…The adhesin NadA favors cell adhesion/invasion by hypervirulent Neisseria meningitidis B (MenB). Its recombinant form NadA(Δ351-405,) devoid of the outer…”
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Data on the stem cells paracrine effects on apoptosis and cytokine milieu in an experimental model of cardiorenal syndrome type II
Published in Data in brief (01-12-2018)“…The data reported in this article are related to the paper entitle “Stem cells transplantation positively modulates the heart-kidney cross talk in Cardiorenal…”
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Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions
Published in Journal of Bacteriology (01-01-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human monocytes/macrophages are a target of Neisseria meningitidis Adhesin A (NadA)
Published in Journal of leukocyte biology (01-05-2008)“…Specific surface proteins of Neisseria meningitidis have been proposed to stimulate leukocytes during tissue invasion and septic shock. In this study, we…”
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Comparison of bactericidal and cytotoxic activities of trichogin analogs
Published in Data in brief (01-03-2016)“…Peptaibiotics are a group of membrane active peptides of fungal origin. They typically contain α-aminoisobutyric acid (Aib; 1-letter code, U) and other…”
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Formyl-Peptide Receptor Agonists and Amorphous SiO2-NPs Synergistically and Selectively Increase the Inflammatory Responses of Human Monocytes and PMNs
Published in Nanobiomedicine (01-01-2016)“…We tested whether amorphous SiO2-NPs and formylpeptide receptor (FPRs) agonists synergistically activate human monocytes and neutrophil polymorphonuclear…”
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Inquiry Based Learning in practice to enhance an Immunological Biotechnologies laboratory experience
Published in Excellence and innovation in teaching and learning (01-12-2023)“…This paper aims to describe a teaching redesign experience that took place through the introduction of the Inquiry Based Learning methodology within the course…”
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Combined Action of Human Commensal Bacteria and Amorphous Silica Nanoparticles on the Viability and Immune Responses of Dendritic Cells
Published in Clinical and vaccine immunology (01-10-2017)“…Dendritic cells (DCs) regulate the host-microbe balance in the gut and skin, tissues likely exposed to nanoparticles (NPs) present in drugs, food, and…”
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The functional dissection of the plasma corona of SiO₂-NPs spots histidine rich glycoprotein as a major player able to hamper nanoparticle capture by macrophages
Published in Nanoscale (14-11-2015)“…A coat of strongly-bound host proteins, or hard corona, may influence the biological and pharmacological features of nanotheranostics by altering their…”
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