Search Results - "TAUC, L"

Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc by Schiavo, G., Poulain, B., Rossetto, O., Benfenati, F., Tauc, L., Montecucco, C.

“…Tetanus and botulinum neurotoxins are the most potent toxins known. They bind to nerve cells, penetrate the cytosol and block neurotransmitter release…”
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Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia by Mothet, J.‐P., Fossier, P., Meunier, F.‐M., Stinnakre, J., Tauc, L., Baux, G.

“…Presynaptic injection of cyclic ADP-ribose (cADPR), a modulator of the ryanodine receptor, increased the postsynaptic response evoked by a presynaptic spike at…”
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Nitric oxide transforms serotonin into an inactive form and this affects neuromodulation by Fossier, P, Blanchard, B, Ducrocq, C, Leprince, C, Tauc, L, Baux, G

“…Nitric oxide is a highly reactive molecule, diffusible and therefore ubiquitous in the central nervous system. Consequently, nitric oxide or nitric…”
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Non vesicular release of neurotransmitter by Tauc, L

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Quantal neurotransmitter release: Vesicular or not vesicular? by Tauc, L.

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Opposite Actions of Nitric Oxide on Cholinergic Synapses: Which Pathways? by Mothet, Jean-Pierre, Fossier, Philippe, Tauc, Ladislav, Baux, Gérard

“…Nitric oxide (NO) produced opposite effects on acetylcholine (ACh) release in identified neuroneuronal Aplysia synapses depending on the excitatory or the…”
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N- and P-type Ca(2 plus) channels are involved in acetylcholine release at a neuroneuronal synapse: Only the N-type channel is the target of neuromodulators by Fossier, P, Baux, G, Tauc, L

“…A study conducted to identify the presynaptic calcium 2plus channels responsible for triggering acetylcholine release at a well-known neuroneuronal synapse of…”
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A role for the interchain disulfide or its participating thiols in the internalization of botulinum neurotoxin A revealed by a toxin derivative that binds to ecto-acceptors and inhibits transmitter release intracellularly by DE PAIVA, A, POULAIN, B, LAWRENCE, G. W, SHONE, C. C, TAUC, L, DOLLY, J. O

“…Botulinum neurotoxin type A consists of a disulfide-linked light and heavy chain, with an intradisulfide present within the C-terminal half of the latter. The…”
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NO decreases evoked quantal ACh release at a synapse of Aplysia by a mechanism independent of Ca2+ influx and protein kinase G by Mothet, J P, Fossier, P, Tauc, L, Baux, G

“…1. The exogenous nitric oxide (NO) donor, SIN-1, decreased the postsynaptic response evoked by a presynaptic spike at an identified cholinergic neuro-neuronal…”
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A nitric oxide synthase activity is involved in the modulation of acetylcholine release in Aplysia ganglion neurons: A histological, voltammetric and electrophysiological study by Meulemans, A., Mothet, J.P., Schirar, A., Fossier, P., Tauc, L., Baux, G.

“…The role of nitric oxide or related molecules as neuromodulators was investigated in the buccal and the abdominal ganglia of the mollusc Aplysia californica…”
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Presynaptic mechanisms regulating Ca2+ concentration triggering acetylcholine release at an identified neuro-neuronal synapse of Aplysia by Fossier, P, Baux, G, Tauc, L

“…We have used an identified cholinergic neuro-neuronal synapse in the buccal ganglion of Aplysia to determine which types of Ca2+ channels are involved in…”
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Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A by KURAZONO, H, MOCHIDA, S, BINZ, T, EISEL, U, QUANZ, M, GREBENSTEIN, O, WERNARS, K, POULAIN, B, TAUC, L, NIEMANN, H

“…To define conserved domains within the light (L) chains of clostridial neurotoxins, we determined the sequence of botulinum neurotoxin type B (BoNT/B) and…”
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Control of the calcium concentration involved in acetylcholine release and its facilitation: an additional role for synaptic vesicles? by Fossier, P, Diebler, M.-F, Mothet, J.-P, Israel, M, Tauc, L, Baux, G

“…2,5-Diterbutyl-1,4-benzohydroquinone, a specific blocker of Ca 2+-ATPase pumps, increased acetylcholine release from an identified synapse of Aplysia, as well…”
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Histamine and FLRFamide regulate acetylcholine release at an identified synapse in Aplysia in opposite ways by Baux, G, Fossier, P, Tauc, L

“…1. The effects of histamine and FLRFamide (Phe-Leu-Arg-Phe-NH2) on acetylcholine (ACh) release were studied in the buccal ganglion of Aplysia californica on an…”
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Neurotransmitter Release is Blocked Intracellularly by Botulinum Neurotoxin, and this Requires Uptake of Both Toxin Polypeptides by a Process Mediated by the Larger Chain by Poulain, B., Tauc, L., Maisey, E. A., Wadsworth, J. D. F., Mohan, P. M., Dolly, J. O.

“…Botulinum neurotoxins (types A and B), which are microbial proteins consisting of two disulfide-linked chains, inhibit specifically and with high potency the…”
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N- and P-Type Ca2+Channels are Involved in Acetylcholine Release at a Neuroneuronal Synapse: Only the N-Type Channel is the Target of Neuromodulators by Fossier, P., Baux, G., Tauc, L.

“…Cholinergic transmission in an identified neuro-neuronal synapse of the Aplysia buccal ganglion was depressed by application of a partially purified extract of…”
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Presynaptic actions of curare and atropine on quantal acetylcholine release at a central synapse of Aplysia by Baux, G, Tauc, L

“…1. In a cholinergic synaptic couple in the buccal ganglion of Aplysia california, where the synaptic areas are situated close to the somata (500 micron), we…”
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Activation of protein kinase C by presynaptic FLRFamide receptors facilitates transmitter release at an aplysia cholinergic synapse by Fossier, P, Baux, G, Tauc, L

“…Modulation of evoked quantal transmitter release by protein kinase C (PKC) was investigated at an identified cholinergic neuro-neuronal synapse of the Aplysia…”
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Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia by POULAIN, B, MOCHIDA, S, WELLER, U, HOGY, B, HABERMANN, E, WADSWORTH, J. D. F, SHONE, C. C, DOLLY, J. O, TAUC, L

“…The neuroparalytic activities of botulinum neurotoxin type A (BoNT A), tetanus toxin (TeTx), or homologous and heterologous combinations of their constituent…”
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Differences in the multiple step process of inhibition of neurotransmitter release induced by tetanus toxin and botulinum neurotoxins type A and B at Aplysia synapses by Poulain, B., De Paiva, A., Deloye, F., Doussau, F., Tauc, L., Weller, U., Dolly, J.O.

“…In order to gain insights into the steps (binding, uptake, intracellular effect) which differ in the inhibitory actions of tetanus toxin and botulinum…”
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