Search Results - "TATE, SIMON N"

A standardized clinical evaluation of phenotypic diversity in diabetic polyneuropathy by Scholz, Joachim, Rathmell, James P., David, William S., Chad, David A., Broderick, Alithia C., Perros, Stephen G., Shin, Naomi S., Wells, Jenna L., Davis, John B., DiMaggio, Charles J., Wang, Shuang, Tate, Simon N.

“…Diabetic polyneuropathy (DPN) is a major cause of neuropathic pain and a frequent target condition in analgesic treatment trials. Differences in the clinical…”
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Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2 by DELANY, NATALIE S, HURLE, MICHAEL, FACER, PAUL, ALNADAF, TANJA, PLUMPTON, CHRISTOPHER, KINGHORN, IAN, SEE, CHEE GEE, COSTIGAN, MICHAEL, ANAND, PRAVEEN, WOOLF, CLIFFORD J, CROWTHER, DANIEL, SANSEAU, PHILIPPE, TATE, SIMON N

“…1 Genome Informatics and Analysis 2 Virology and Vaccine Systems 3 Ion Channel Section 4 Molecular Recognition 5 Molecular Genetics, Glaxo Wellcome Research…”
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Upregulation of the Voltage-Gated Sodium Channel β2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J., Karchewski, Laurie, Tate, Simon N., Isom, Lori L., Woolf, Clifford J., Gilliard, Nicolas, Spahn, Donat R., Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum by Chen, Mao Xiang, Gorman, Shelby A, Benson, Bill, Singh, Kuljit, Hieble, J Paul, Michel, Martin C, Tate, Simon N, Trezise, Derek J

“…The SK/IK family of small and intermediate conductance calcium-activated potassium channels contains four members, SK1, SK2, SK3 and IK1, and is important for…”
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Voltage-gated sodium channels as therapeutic targets by Clare, Jeffrey J., Tate, Simon N., Nobbs, Malcolm, Romanos, Mike A.

“…Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of action potentials in neurons and other cells. VGSC modulators…”
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Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding by Scheib, Holger, McLay, Iain, Guex, Nicolas, Clare, Jeff J, Blaney, Frank E, Dale, Tim J, Tate, Simon N, Robertson, Graeme M

“…In this work molecular modeling was applied to generate homology models of the pore region of the Na(v)1.2 and Na(v)1.8 isoforms of human voltage-gated sodium…”
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Expression of the sodium channel β3 subunit in injured human sensory neurons by Casula, Maria A, Facer, Paul, Powell, Andrew J, Kinghorn, Ian J, Plumpton, Christopher, Tate, Simon N, Bountra, Chas, Birch, Rolfe, Anand, Praveen

“…Voltage-gated sodium channel α-subunits play a key role in pain pathophysiology, and are modulated by β-subunits. We previously reported that β1- and…”
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Decreased potassium channel IKI and its regulator neurotrophin-3 (NT-3) in inflamed human bowel by ARNOLD, Steven J, FACER, Paul, YIANGOS YIANGOU, CHEN, Mark X, PLUMPTON, Christopher, TATE, Simon N, BOUNTRA, Chas, CHAN, Christopher L. H, WILLIAMS, Norman S, ANAND, Praveen

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Decreased potassium channel IK1 and its regulator neurotrophin-3 (NT-3) in inflamed human bowel by Arnold, Steven J, Facer, Paul, Yiangou, Yiangos, Chen, Mark X, Plumpton, Christopher, Tate, Simon N, Bountra, Chas, Chan, Christopher L. H, Williams, Norman S, Anand, Praveen

“…Calcium-activated potassium currents of intermediate conductance (IK1) have been described in the rodent enteric nervous system, where they may regulate…”
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Upregulation of the Voltage-Gated Sodium Channel beta 2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Small and intermediate conductance Ca 2+ -activated K + channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum by Chen, Mao Xiang, Gorman, Shelby A., Benson, Bill, Singh, Kuljit, Hieble, J. Paul, Michel, Martin C., Tate, Simon N., Trezise, Derek J.

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Expression of the sodium channel beta3 subunit in injured human sensory neurons by Casula, Maria A, Facer, Paul, Powell, Andrew J, Kinghorn, Ian J, Plumpton, Christopher, Tate, Simon N, Bountra, Chas, Birch, Rolfe, Anand, Praveen

“…Voltage-gated sodium channel alpha-subunits play a key role in pain pathophysiology, and are modulated by beta-subunits. We previously reported that beta1- and…”
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Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Mechanism of Action of Anticonvulsants as Analgesic Drugs by Morisset, Valerie, Davis, John B, Tate, Simon N

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Upregulation of the Voltage-Gated Sodium Channel {beta}2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

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