Search Results - "TARWATER, Patrick M"

Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms by Arab, Tanina, Mallick, Emily R., Huang, Yiyao, Dong, Liang, Liao, Zhaohao, Zhao, Zezhou, Gololobova, Olesia, Smith, Barbara, Haughey, Norman J., Pienta, Kenneth J., Slusher, Barbara S., Tarwater, Patrick M., Tosar, Juan Pablo, Zivkovic, Angela M., Vreeland, Wyatt N., Paulaitis, Michael E., Witwer, Kenneth W.

“…We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles. The platforms were:…”
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The Effect of Latency Reversal Agents on Primary CD8+ T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication by Walker-Sperling, Victoria E., Pohlmeyer, Christopher W., Tarwater, Patrick M., Blankson, Joel N.

“…Shock and kill strategies involving the use of small molecules to induce viral transcription in resting CD4+ T cells (shock) followed by immune mediated…”
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Aggression toward Familiar People, Strangers, and Conspecifics in Gonadectomized and Intact Dogs by Farhoody, Parvene, Mallawaarachchi, Indika, Tarwater, Patrick M, Serpell, James A, Duffy, Deborah L, Zink, Chris

“…Gonadectomy is widely used to treat and prevent behavior problems including the aggressive behavior of dogs. The aim of this study was to determine whether…”
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Adeno-Associated Virus (AAV)-Delivered Exosomal TAT and BiTE Molecule CD4-αCD3 Facilitate the Elimination of CD4 T Cells Harboring Latent HIV-1 by Tang, Xiaoli, Lu, Huafei, Tarwater, Patrick M, Silverberg, David L, Schorl, Christoph, Ramratnam, Bharat

“…Combinatorial antiretroviral therapy (cART) has transformed HIV infection from a death sentence to a controllable chronic disease, but cannot eliminate the…”
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Coordinated regulation of SIV replication and immune responses in the CNS by Witwer, Kenneth W, Gama, Lucio, Li, Ming, Bartizal, Christopher M, Queen, Suzanne E, Varrone, John J, Brice, Angela K, Graham, David R, Tarwater, Patrick M, Mankowski, Joseph L, Zink, M Christine, Clements, Janice E

“…Central nervous system (CNS) invasion during acute-stage HIV-infection has been demonstrated in a small number of individuals, but there is no evidence of…”
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Simian Immunodeficiency Virus-Infected Macaques Treated with Highly Active Antiretroviral Therapy Have Reduced Central Nervous System Viral Replication and Inflammation but Persistence of Viral DNA by Zink, M. Christine, Brice, Angela K., Kelly, Kathleen M., Queen, Suzanne E., Gama, Lucio, Li, Ming, Adams, Robert J., Bartizal, Christopher, Varrone, John, Rabi, S. Alireza, Graham, David R., Tarwater, Patrick M., Mankowski, Joseph L., Clements, Janice E.

“…Background. During the era of highly active antiretroviral therapy (HAART), the prevalence of HIV-associated central nervous system (CNS) disease has increased…”
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Association between Quality of Maternal Prenatal Food Source and Preparation and Breastfeeding Duration in the Environmental Influences on Child Health Outcome (ECHO) Program by Zimmerman, Emily, Gachigi, Kennedy K, Rodgers, Rachel F, Watkins, Deborah J, Woodbury, Megan, Cordero, José F, Alshawabkeh, Akram, Meeker, John D, Huerta-Montañez, Gredia, Pabon, Zaira Rosario, Hines, Morgan, Velez-Vega, Carmen M, Camargo, Jr, Carlos A, Zhu, Yeyi, Nozadi, Sara S, Comstock, Sarah S, Hockett, Christine, Tarwater, Patrick M, On Behalf Of Program Collaborators For Environmental Influences On Child Health Outcomes

“…This study examined the relationship between maternal food source and preparation during pregnancy and the duration of breastfeeding among 751 mother-child…”
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Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment by Qin, Shulin, Alcorn, John F, Craigo, Jodi K, Tjoeng, Charis, Tarwater, Patrick M, Kolls, Jay K, Reinhart, Todd A

“…One major activity of chemokines is the recruitment of immune cells to sites of infection and inflammation. CD4(+) Th1 cells play critical roles in host…”
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The Evi1, microRNA-143, K-Ras axis in colon cancer by Gao, Jin-Song, Zhang, Yingjie, Tang, Xiaoli, Tucker, Lynne D., Tarwater, Patrick M., Quesenberry, Peter J., Rigoutsos, Isidore, Ramratnam, Bharat

“…MicroRNA profiling of diseased/non-diseased tissue has identified expression signatures associated with a wide range of pathogenic conditions including…”
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Return of Memory and Sleep Efficiency Following Moderate to Severe Closed Head Injury by Makley, Michael J., Johnson-Greene, Lisa, Tarwater, Patrick M., Kreuz, Andrew J., Spiro, J., Rao, V., Celnik, Pablo A.

“…Objective. Sleep disturbance is common in the subacute recovery phase following brain injury. A previous study from the authors' group found 68% of patients…”
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Mechanism for the Establishment of Transcriptional HIV Latency in the Brain in a Simian Immunodeficiency Virus–Macaque Model by Barber, Sheila A., Gama, Lucio, Dudaronek, Justyna M., Voelker, Tauni, Tarwater, Patrick M., Clements, Janice E.

“…BackgroundThe brain is considered to be a reservoir of latent human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). We examined the…”
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A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion by Wood, Matthew P, Cole, Amy L, Ruchala, Piotr, Waring, Alan J, Rohan, Lisa C, Marx, Preston, Tarwater, Patrick M, Gupta, Phalguni, Cole, Alexander M

“…Fusion inhibitors are a class of antiretroviral drugs used to prevent entry of HIV into host cells. Many of the fusion inhibitors being developed, including…”
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The Central Nervous System as a Reservoir for Simian Immunodeficiency Virus (SIV): Steady-State Levels of SIV DNA in Brain from Acute through Asymptomatic Infection by Clements, Janice E., Babas, Tahar, Mankowski, Joseph L., Suryanarayana, K., Piatak, Michael, Tarwater, Patrick M., Lifson, Jeffrey D., Zink, M. Christine

“…Latent reservoirs of human immunodeficiency virus (HIV) present significant challenges for eradicating HIV from infected persons, particularly reservoirs in…”
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High replication fitness and transmission efficiency of HIV-1 subtype C from India: Implications for subtype C predominance by Rodriguez, Milka A, Ding, Ming, Ratner, Deena, Chen, Yue, Tripathy, Srikanth P, Kulkarni, Smita S, Chatterjee, Ramdas, Tarwater, Patrick M, Gupta, Phalguni

“…Abstract HIV-1 subtype C has been the predominant subtype throughout the course of the HIV-1 epidemic in India regardless of the geographic region of the…”
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Incorporation of the HIV-1 Microbicide Cyanovirin-N in a Food Product by Li, Ming, Patton, Dorothy L, Cosgrove-Sweeney, Yvonne, Ratner, Deena, Rohan, Lisa C, Cole, Alexander M, Tarwater, Patrick M, Gupta, Phalguni, Ramratnam, Bharat

“…ABSTRACTAn urgent need exists for HIV-1 microbicides. Here, we describe the in vivo testing of lactic acid bacteria bioengineered to secrete cyanovirin-N. We…”
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Increased Macrophage Chemoattractant Protein-1 in Cerebrospinal Fluid Precedes and Predicts Simian Immunodeficiency Virus Encephalitis by Zink, M. Christine, Coleman, Gary D., Mankowski, Joseph L., Adams, Robert J., Tarwater, Patrick M., Fox, Kelly, Clements, Janice E.

“…Macrophage chemoattractant protein–1 (MCP-1) may be a key trigger for the influx of macrophages into the brain in human immunodeficiency virus (HIV)…”
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Cigarette smoke-induced extracellular vesicles from dendritic cells alter T-cell activation and HIV replication by Russell, Ashley E., Liao, Zhaohao, Tkach, Mercedes, Tarwater, Patrick M., Ostrowski, Matias, Théry, Clotilde, Witwer, Kenneth W.

“…Exposure to CSE significantly increases release of iDC-EVs. These EVs can push Th0 T-cells towards the Th17 or Th1 phenotype. These EVs can also reduce p24…”
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Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques by Mankowski, Joseph L, Queen, Suzanne E, Fernandez, Caroline S, Tarwater, Patrick M, Karper, Jami M, Adams, Robert J, Kent, Stephen J

“…Human immunodeficiency virus (HIV) infection frequently causes neurologic disease even with anti-retroviral treatment. Although associations between MHC class…”
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Longitudinal Analysis of Simian Immunodeficiency Virus (SIV) Replication in the Lungs: Compartmentalized Regulation of SIV by Barber, Sheila A., Gama, Lucio, Li, Ming, Voelker, Tauni, Anderson, John E., Zink, M. Christine, Tarwater, Patrick M., Carruth, Lucy M., Clements, Janice E.

“…BackgroundBefore the onset of AIDS, replication of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) in the lungs is considered to be…”
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Progression and Resolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Golden Syrian Hamsters by Mulka, Kathleen R., Beck, Sarah E., Solis, Clarisse V., Johanson, Andrew L., Queen, Suzanne E., McCarron, Megan E., Richardson, Morgan R., Zhou, Ruifeng, Marinho, Paula, Jedlicka, Anne, Guerrero-Martin, Selena, Shirk, Erin N., Braxton, Alicia M., Brockhurst, Jacqueline, Creisher, Patrick S., Dhakal, Santosh, Brayton, Cory F., Veenhuis, Rebecca T., Metcalf Pate, Kelly A., Karakousis, Petros C., Zahnow, Cynthia A., Klein, Sabra L., Jain, Sanjay K., Tarwater, Patrick M., Pekosz, Andrew S., Villano, Jason S., Mankowski, Joseph L., Betenbaugh, Michael J., Carlson, Bess, Castell, Natalie, Castillo, Jennie Ruelas, Flavahan, Kelly, Hutchinson, Eric K., Littlefield, Kirsten, Looney, Monika M., Lowman, Maggie, Majewski, Natalia, Maxwell, Amanda, Mota, Filipa, Mueller, Alice L., Ordonez, Alvaro A., Pieterse, Lisa, Quijada, Darla, Ruiz-Bedoya, Camilo A., Stover, Mitchel, Vistein, Rachel, Wood, Melissa

“…To catalyze severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) research, including development of novel interventive and preventive strategies, the…”
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