Search Results - "TARR, Phillip I"
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Early pregnancy vaginal microbiome trends and preterm birth
Published in American journal of obstetrics and gynecology (01-09-2017)“…Background Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive…”
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Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
Published in Gut (01-06-2015)“…The technology for the growth of human intestinal epithelial cells is rapidly progressing. An exciting possibility is that this system could serve as a…”
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3
Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes
Published in Nature medicine (01-12-2018)“…Commensal gut bacterial communities (microbiomes) are predicted to influence human health and disease 1 , 2 . Neonatal gut microbiomes are colonized with…”
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Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study
Published in The Lancet (British edition) (07-05-2016)“…Summary Background Gut bacteria might predispose to or protect from necrotising enterocolitis, a severe illness linked to prematurity. In this observational…”
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Early life dynamics of the human gut virome and bacterial microbiome in infants
Published in Nature medicine (01-10-2015)“…Colonization of the infant gut by viruses, bacteriophages and bacteria over the first two years of life. The early years of life are important for immune…”
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2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea
Published in Clinical infectious diseases (15-12-2017)“…These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea. They are…”
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Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice
Published in Nature (London) (09-06-2016)“…The relationship between assembly of the gut community and gut mucosal immunoglobulin A responses during the first 24–36 months of postnatal life in a cohort…”
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2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea
Published in Clinical infectious diseases (29-11-2017)“…These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea. They are…”
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Patterned progression of bacterial populations in the premature infant gut
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2014)“…In the weeks after birth, the gut acquires a nascent microbiome, and starts its transition to bacterial population equilibrium. This early-in-life microbial…”
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Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis
Published in Microbiome (09-03-2017)“…Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and microbial dysbiosis has been implicated in its pathogenesis. Studies…”
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Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
Published in The Lancet (British edition) (19-03-2005)“…Most cases of diarrhoea-associated haemolytic uraemic syndrome (HUS) are caused by Shiga-toxin-producing bacteria; the pathophysiology differs from that of…”
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Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes
Published in PloS one (13-11-2013)“…Emerging antibiotic resistance threatens human health. Gut microbes are an epidemiologically important reservoir of resistance genes (resistome), yet prior…”
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Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome
Published in Nature microbiology (07-03-2016)“…Development of the preterm infant gut microbiota is emerging as a critical research priority 1 . Since preterm infants almost universally receive early and…”
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Metagenomic analysis of human diarrhea: viral detection and discovery
Published in PLoS pathogens (29-02-2008)“…Worldwide, approximately 1.8 million children die from diarrhea annually, and millions more suffer multiple episodes of nonfatal diarrhea. On average, in up to…”
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Biogeography of the ecosystems of the healthy human body
Published in Genome biology (14-01-2013)“…BACKGROUND: Characterizing the biogeography of the microbiome of healthy humans is essential for understanding microbial associated diseases. Previous studies…”
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Maternal obesogenic diet enhances cholestatic liver disease in offspring
Published in Journal of lipid research (01-05-2022)“…Human and animal model data show that maternal obesity promotes nonalcoholic fatty liver disease in offspring and alters bile acid (BA) homeostasis. Here we…”
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Discordant transmission of bacteria and viruses from mothers to babies at birth
Published in Microbiome (10-12-2019)“…The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and…”
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Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria
Published in Science immunology (15-12-2017)“…We have a mutually beneficial relationship with the trillions of microorganisms inhabiting our gastrointestinal tract. However, maintaining this relationship…”
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Microbiome-targeting therapies in the neonatal intensive care unit: safety and efficacy
Published in Gut microbes (31-12-2023)“…Microbiome-targeting therapies have received great attention as approaches to prevent disease in infants born preterm, but their safety and efficacy remain…”
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A novel histological index for evaluation of environmental enteric dysfunction identifies geographic-specific features of enteropathy among children with suboptimal growth
Published in PLoS neglected tropical diseases (01-01-2020)“…A major limitation to understanding the etiopathogenesis of environmental enteric dysfunction (EED) is the lack of a comprehensive, reproducible histologic…”
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