Search Results - "TARGOWNIK, L. E."
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A comparison of the gut microbiome between long‐term users and non‐users of proton pump inhibitors
Published in Alimentary pharmacology & therapeutics (01-05-2016)“…Summary Background Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is…”
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The effect of proton pump inhibitors on fracture risk: report from the Canadian Multicenter Osteoporosis Study
Published in Osteoporosis international (01-04-2013)“…Summary A large Canadian cohort was studied over 10 years to see if proton pump inhibitor (PPI) use increased the risk of sustaining a fragility fracture. We…”
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Independent Validation of a Self-Report Version of the IBD Disability Index (IBDDI) in a Population-Based Cohort of IBD Patients
Published in Inflammatory bowel diseases (19-03-2018)“…Abstract Introduction A new clinician-administered inflammatory bowel disease (IBD) Disability Index (IBDDI) was recently developed and validated among a…”
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Predicting complicated Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population‐based cohort
Published in Alimentary pharmacology & therapeutics (01-08-2013)“…Summary Background Predictors of complicated Crohn's disease (CD), defined as stricturing or penetrating behaviour, and surgery have largely been derived from…”
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Gastrointestinal symptoms before and during menses in women with IBD
Published in Alimentary pharmacology & therapeutics (01-07-2012)“…Summary Background It is believed that women with inflammatory bowel disease (IBD) have heightened symptoms around their menses. However, there is little…”
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Differences in the management of Crohn’s disease among experts and community providers, based on a national survey of sample case vignettes
Published in Alimentary pharmacology & therapeutics (01-10-2007)“…Summary Background When faced with the same set of facts, healthcare providers often make different diagnoses, employ different tests and prescribe disparate…”
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Editorial: let's take a break from studying the PPI‐fracture association
Published in Alimentary pharmacology & therapeutics (01-06-2018)“…Linked Content This article is linked to Torvinen‐Kiiskinen et al papers. To view these articles visit https://doi.org/10.1111/apt.14589 and…”
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Editorial: Non‐breaking news! High‐dose PPIs likely do not cause fractures
Published in Alimentary pharmacology & therapeutics (01-01-2018)“…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345…”
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Pre‐endoscopic proton pump inhibitor therapy reduces recurrent adverse gastrointestinal outcomes in patients with acute non‐variceal upper gastrointestinal bleeding
Published in Alimentary pharmacology & therapeutics (15-10-2006)“…Summary Background Proton pump inhibitors (PPIs) following endoscopic haemostasis reduce rebleeding rates in patients with high‐risk acute non‐variceal upper…”
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Underutilization of gastroprotective strategies in aspirin users at increased risk of upper gastrointestinal complications
Published in Alimentary pharmacology & therapeutics (01-07-2008)“…Summary Background Aspirin use is with an increased risk of upper gastrointestinal complications (UGICs). Proton pump inhibitors (PPIs) decrease the risk of…”
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Physicians’ approaches to the use of gastroprotective strategies in low‐risk non‐steroidal anti‐inflammatory drug users
Published in Alimentary pharmacology & therapeutics (01-05-2006)“…Summary Background Many doctors unnecessarily prescribe gastroprotective strategies to non‐steroidal anti‐inflammatory drugs users at low risk of non‐steroidal…”
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The prevalence of risk factors for gastrointestinal complications and use of gastroprotection among persons hospitalized for cardiovascular disease
Published in Alimentary pharmacology & therapeutics (15-03-2006)“…Summary Background Aspirin is often used in patients with cardiovascular disease, but it can also cause gastrointestinal complications. Proton pump inhibitors…”
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Use of proton pump inhibitors and risk of osteoporosis-related fractures
Published in Canadian Medical Association journal (CMAJ) (12-08-2008)“…The use of proton pump inhibitors has been associated with an increased risk of hip fracture. We sought to further explore the relation between duration of…”
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Editorial: Non‐breaking news! High‐dose PPI s likely do not cause fractures
Published in Alimentary pharmacology & therapeutics (01-01-2018)“…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345 …”
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An assessment of endoscopic and concomitant management of acute variceal bleeding at a tertiary care centre
Published in Canadian journal of gastroenterology (01-02-2007)“…Several therapies have been demonstrated to be beneficial in the management of acute variceal bleeding (AVB). The aim of the present study was to characterize…”
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P725 Trends in biologic use prior to resective surgery for inflammatory bowel disease: A Canadian population-based study
Published in Journal of Crohn's and colitis (15-01-2020)“…Abstract Background Despite advances in medical therapy for inflammatory bowel disease (IBD), surgery is required in 50–80% of patients with Crohn’s disease…”
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Immortal time bias and infliximab-related mortality and malignancy incidence
Published in Gut (01-03-2010)Get more information
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