Search Results - "TARGOWNIK, L. E."

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    A comparison of the gut microbiome between long‐term users and non‐users of proton pump inhibitors by Clooney, A. G., Bernstein, C. N, Leslie, W. D., Vagianos, K., Sargent, M., Laserna‐Mendieta, E. J., Claesson, M. J., Targownik, L. E.

    Published in Alimentary pharmacology & therapeutics (01-05-2016)
    “…Summary Background Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is…”
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    Journal Article
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    The effect of proton pump inhibitors on fracture risk: report from the Canadian Multicenter Osteoporosis Study by Fraser, L-A., Leslie, W. D., Targownik, L. E., Papaioannou, A., Adachi, J. D.

    Published in Osteoporosis international (01-04-2013)
    “…Summary A large Canadian cohort was studied over 10 years to see if proton pump inhibitor (PPI) use increased the risk of sustaining a fragility fracture. We…”
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    Journal Article
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    Independent Validation of a Self-Report Version of the IBD Disability Index (IBDDI) in a Population-Based Cohort of IBD Patients by Shafer, LA, Walker, JR, Chhibba, T, Ivekovic, M, Singh, H, Targownik, LE, Peyrin-Biroulet, L, Gower-Rousseau, C, Sarter, H, Bernstein, CN

    Published in Inflammatory bowel diseases (19-03-2018)
    “…Abstract Introduction A new clinician-administered inflammatory bowel disease (IBD) Disability Index (IBDDI) was recently developed and validated among a…”
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    Journal Article
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    Predicting complicated Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population‐based cohort by Ryan, J. D., Silverberg, M. S., Xu, W., Graff, L. A., Targownik, L. E., Walker, J. R., Carr, R., Clara, I., Miller, N., Rogala, L., Bernstein, C. N.

    Published in Alimentary pharmacology & therapeutics (01-08-2013)
    “…Summary Background Predictors of complicated Crohn's disease (CD), defined as stricturing or penetrating behaviour, and surgery have largely been derived from…”
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    Journal Article
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    Gastrointestinal symptoms before and during menses in women with IBD by Bernstein, M. T., Graff, L. A., Targownik, L. E., Downing, K., Shafer, L. A., Rawsthorne, P., Bernstein, C. N., Avery, L.

    Published in Alimentary pharmacology & therapeutics (01-07-2012)
    “…Summary Background It is believed that women with inflammatory bowel disease (IBD) have heightened symptoms around their menses. However, there is little…”
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    Differences in the management of Crohn’s disease among experts and community providers, based on a national survey of sample case vignettes by ESRAILIAN, E., SPIEGEL, B. M. R., TARGOWNIK, L. E., DUBINSKY, M. C., TARGAN, S. R., GRALNEK, I. M.

    Published in Alimentary pharmacology & therapeutics (01-10-2007)
    “…Summary Background  When faced with the same set of facts, healthcare providers often make different diagnoses, employ different tests and prescribe disparate…”
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    Editorial: let's take a break from studying the PPI‐fracture association by Targownik, L. E.

    Published in Alimentary pharmacology & therapeutics (01-06-2018)
    “…Linked Content This article is linked to Torvinen‐Kiiskinen et al papers. To view these articles visit https://doi.org/10.1111/apt.14589 and…”
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    Journal Article
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    Editorial: Non‐breaking news! High‐dose PPIs likely do not cause fractures by Targownik, L. E.

    Published in Alimentary pharmacology & therapeutics (01-01-2018)
    “…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345…”
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    Journal Article
  9. 9

    Pre‐endoscopic proton pump inhibitor therapy reduces recurrent adverse gastrointestinal outcomes in patients with acute non‐variceal upper gastrointestinal bleeding by KEYVANI, L., MURTHY, S., LEESON, S., TARGOWNIK, L. E.

    Published in Alimentary pharmacology & therapeutics (15-10-2006)
    “…Summary Background Proton pump inhibitors (PPIs) following endoscopic haemostasis reduce rebleeding rates in patients with high‐risk acute non‐variceal upper…”
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    Journal Article
  10. 10

    Underutilization of gastroprotective strategies in aspirin users at increased risk of upper gastrointestinal complications by TARGOWNIK, L. E., METGE, C. J., LEUNG, S.

    Published in Alimentary pharmacology & therapeutics (01-07-2008)
    “…Summary Background  Aspirin use is with an increased risk of upper gastrointestinal complications (UGICs). Proton pump inhibitors (PPIs) decrease the risk of…”
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    Journal Article
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    Physicians’ approaches to the use of gastroprotective strategies in low‐risk non‐steroidal anti‐inflammatory drug users by MURTHY, S. K., KAULDHER, S., TARGOWNIK, L. E.

    Published in Alimentary pharmacology & therapeutics (01-05-2006)
    “…Summary Background Many doctors unnecessarily prescribe gastroprotective strategies to non‐steroidal anti‐inflammatory drugs users at low risk of non‐steroidal…”
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    Journal Article
  12. 12

    The prevalence of risk factors for gastrointestinal complications and use of gastroprotection among persons hospitalized for cardiovascular disease by TARGOWNIK, L. E., AL‐MAMFUD, A.

    Published in Alimentary pharmacology & therapeutics (15-03-2006)
    “…Summary Background Aspirin is often used in patients with cardiovascular disease, but it can also cause gastrointestinal complications. Proton pump inhibitors…”
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    Journal Article
  13. 13

    Use of proton pump inhibitors and risk of osteoporosis-related fractures by Targownik, Laura E, Lix, Lisa M, Metge, Colleen J, Prior, Heather J, Leung, Stella, Leslie, William D

    “…The use of proton pump inhibitors has been associated with an increased risk of hip fracture. We sought to further explore the relation between duration of…”
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  14. 14

    Editorial: Non‐breaking news! High‐dose PPI s likely do not cause fractures by Targownik, L. E.

    Published in Alimentary pharmacology & therapeutics (01-01-2018)
    “…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345 …”
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    Journal Article
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    An assessment of endoscopic and concomitant management of acute variceal bleeding at a tertiary care centre by Singh, H, Targownik, L E, Ward, G, Minuk, G Y, Bernstein, C N

    Published in Canadian journal of gastroenterology (01-02-2007)
    “…Several therapies have been demonstrated to be beneficial in the management of acute variceal bleeding (AVB). The aim of the present study was to characterize…”
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    P725 Trends in biologic use prior to resective surgery for inflammatory bowel disease: A Canadian population-based study by Chopra, D, Kennedy, E, Weizman, A V, Tennakoon, A, Targownik, L E

    Published in Journal of Crohn's and colitis (15-01-2020)
    “…Abstract Background Despite advances in medical therapy for inflammatory bowel disease (IBD), surgery is required in 50–80% of patients with Crohn’s disease…”
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