Search Results - "TAOUJI, Said"

Genomic Profiling of Hepatocellular Adenomas Reveals Recurrent FRK-Activating Mutations and the Mechanisms of Malignant Transformation by Pilati, Camilla, Letouzé, Eric, Nault, Jean-Charles, Imbeaud, Sandrine, Boulai, Anaïs, Calderaro, Julien, Poussin, Karine, Franconi, Andrea, Couchy, Gabrielle, Morcrette, Guillaume, Mallet, Maxime, Taouji, Saïd, Balabaud, Charles, Terris, Benoit, Canal, Frédéric, Paradis, Valérie, Scoazec, Jean-Yves, de Muret, Anne, Guettier, Catherine, Bioulac-Sage, Paulette, Chevet, Eric, Calvo, Fabien, Zucman-Rossi, Jessica

“…Hepatocellular adenomas (HCA) are benign liver tumors predominantly developed in women using oral contraceptives. Here, exome sequencing identified recurrent…”
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Hepatocellular adenoma subtypes: the impact of overweight and obesity by Bioulac-Sage, Paulette, Taouji, Said, Possenti, Laurent, Balabaud, Charles

“…Background Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women using oral contraceptives. With the appearance of a generation of…”
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Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design by Mazella, Jean, Pétrault, Olivier, Lucas, Guillaume, Deval, Emmanuel, Béraud-Dufour, Sophie, Gandin, Carine, El-Yacoubi, Malika, Widmann, Catherine, Guyon, Alice, Chevet, Eric, Taouji, Said, Conductier, Grégory, Corinus, Alain, Coppola, Thierry, Gobbi, Gabriella, Nahon, Jean-Louis, Heurteaux, Catherine, Borsotto, Marc

“…Current antidepressant treatments are inadequate for many individuals, and when they are effective, they require several weeks of administration before a…”
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First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay by Elkaim, Judith, Castroviejo, Michel, Bennani, Driss, Taouji, Said, Allain, Nathalie, Laguerre, Michel, Rosenbaum, Jean, Dessolin, Jean, Lestienne, Patrick

“…The human protein Pontin, which belongs to the AAA+ (ATPases associated with various cellular activities) family, is overexpressed in several cancers and its…”
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Dimerization capacities of FGF2 purified with or without heparin-affinity chromatography by Platonova, Natalia, Miquel, Géraldine, Chiu, Liang-Yuan, Taouji, Said, Moroni, Elisabetta, Colombo, Giorgio, Chevet, Eric, Sue, Shih-Che, Bikfalvi, Andreas

“…Fibroblast growth factor-2 (FGF2) is a pleiotropic growth factor exhibiting a variety of biological activities. In this article, we studied the capacity of…”
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Allosteric Inhibition of HER2 by Moesin-Mimicking Compounds Targets HER2-Positive Cancers and Brain Metastases by Faure, Camille, Djerbi-Bouillié, Rym, Domingot, Anaïs, Bouzinba-Segard, Haniaa, Taouji, Saïd, Saidi, Yanis, Bernard, Sandra, Carallis, Floriane, Rothe-Walther, Romy, Lenormand, Jean-Luc, Chevet, Eric, Bourdoulous, Sandrine

“…Therapies targeting the tyrosine kinase receptor HER2 have significantly improved survival of patients with HER2 cancer. However, both and acquired resistance…”
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Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration by Torres, Chloé, Garling, Asja, Taouji, Saïd, Calmels, Christina, Andreola, Marie-Line, Métifiot, Mathieu

“…Multiple viral targets are now available in the clinic to fight HIV infection. Even if this targeted therapy is highly effective at suppressing viral…”
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P97/CDC-48: Proteostasis control in tumor cell biology by Fessart, Delphine, Marza, Esther, Taouji, Saïd, Delom, Frédéric, Chevet, Eric

“…Highlights • P97/CDC-48 is a member of the AAA+ ATPase family. • P97/CDC-48 is involved in numerous cellular process through its binding to accessory proteins…”
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Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization by Bernard, Sandra C, Simpson, Nandi, Join-Lambert, Olivier, Federici, Christian, Laran-Chich, Marie-Pierre, Maïssa, Nawal, Bouzinba-Ségard, Haniaa, Morand, Philippe C, Chretien, Fabrice, Taouji, Saïd, Chevet, Eric, Janel, Sébastien, Lafont, Frank, Coureuil, Mathieu, Segura, Audrey, Niedergang, Florence, Marullo, Stefano, Couraud, Pierre-Olivier, Nassif, Xavier, Bourdoulous, Sandrine

“…Neisseria meningitidis is the causative agent of potentially fatal meningitis and septic shock, induced by bacterial colonization of blood vessels in the brain…”
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H2O2, Which Causes Macrophage-Related Stress, Triggers Induction of Expression of Virulence-Associated Plasmid Determinants in Rhodococcus equi by BENOIT, Stephanie, BENACHOUR, Abdellah, TAOUJI, Said, AUFFRAY, Yanick, HARTKE, Axel

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Induction of vap genes encoded by the virulence plasmid of Rhodococcus equi during acid tolerance response by Benoit, Stéphanie, Benachour, Abdellah, Taouji, Said, Auffray, Yanick, Hartke, Axel

“…The response of the intracellular pathogen Rhodococcus equi to acid shock, a stress potentially encountered after phagocytosis by macrophages, was analyzed…”
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MicroRNA-1291-mediated silencing of IRE1α enhances Glypican-3 expression by Maurel, Marion, Dejeans, Nicolas, Taouji, Saïd, Chevet, Eric, Grosset, Christophe F

“…MicroRNAs (miRNA) are generally described as negative regulators of gene expression. However, some evidence suggests that they may also play positive roles. As…”
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Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes by Bioulac-Sage, Paulette, Cubel, Gaelle, Taouji, Saïd, Scoazec, Jean-Yves, Leteurtre, Emmanuelle, Paradis, Valérie, Sturm, Nathalie, Nhieu, Jeanne Tran Van, Wendum, Dominique, Bancel, Brigitte, Ramos, Jeanne, Paraf, François, Saint Paul, Marie Christine, Michalak, Sophie, Fabre, Monique, Guettier, Catherine, Le Bail, Brigitte, Zucman-Rossi, Jessica, Balabaud, Charles

“…Phenotypic identification of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) subtypes using immunohistochemical markers has been developed…”
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Phosphorylation of Serine Palmitoyltransferase Long Chain-1 (SPTLC1) on Tyrosine 164 Inhibits Its Activity and Promotes Cell Survival by Taouji, Saïd, Higa, Arisa, Delom, Frédéric, Palcy, Sandrine, Mahon, François-Xavier, Pasquet, Jean-Max, Bossé, Roger, Ségui, Bruno, Chevet, Eric

“…In BCR-ABL-expressing cells, sphingolipid metabolism is altered. Because the first step of sphingolipid biosynthesis occurs in the endoplasmic reticulum (ER),…”
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Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance by Higa, Arisa, Taouji, Said, Lhomond, Stéphanie, Jensen, Devon, Fernandez-Zapico, Martin E., Simpson, Jeremy C., Pasquet, Jean-Max, Schekman, Randy, Chevet, Eric

“…ATF6α, a membrane-anchored transcription factor from the endoplasmic reticulum (ER) that modulates the cellular response to stress as an effector of the…”
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Adaptation of the secretory pathway in cancer through IRE1 signaling by Lhomond, Stéphanie, Pallares, Nestor, Barroso, Kim, Schmit, Kathleen, Dejeans, Nicolas, Fazli, Hélèna, Taouji, Saïd, Patterson, John B, Chevet, Eric

“…The unfolded protein response (UPR) was originally identified as a signaling network coordinating adaptive and apoptotic responses to accumulation of unfolded…”
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Current Screens Based on the AlphaScreen™ Technology for Deciphering Cell Signalling Pathways by Taouji, Saïd, Dahan, Sophie, Bossé, Roger, Chevet, Eric

“…Global deciphering of signal transduction pathways represents a new challenge of the post-genomic era. However, for the majority of these signaling pathways…”
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Using AlphaScreen(®) to Identify Small-Molecule Inhibitors Targeting a Conserved Host-Pathogen Interaction by Austin, Sisley, Taouji, Saïd, Chevet, Eric, Wodrich, Harald, Rayne, Fabienne

“…AlphaScreen(®) is a technology particularly suitable for bi-molecular inhibitor screening assays, e.g. using protein-protein interactions with purified…”
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Systematic functional analysis of the Ras GTPase family unveils a conserved network required for anterograde protein trafficking by Caruso, Marie‐Elaine, Jenna, Sarah, Baillie, David L, Bossé, Roger, Simpson, Jeremy C., Chevet, Eric, Taouji, Saïd

“…Phylogeny is often used to compare entire families of genes/proteins. We previously showed that classification of Caenorhabditis elegans Rho GTPases on the…”
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Genome-wide screen identifies a novel p97/CDC-48-dependent pathway regulating ER-stress-induced gene transcription by Marza, Esther, Taouji, Saïd, Barroso, Kim, Raymond, Anne-Aurélie, Guignard, Léo, Bonneu, Marc, Pallares-Lupon, Néstor, Dupuy, Jean-William, Fernandez-Zapico, Martin E, Rosenbaum, Jean, Palladino, Francesca, Dupuy, Denis, Chevet, Eric

“…The accumulation of misfolded proteins in the endoplasmic reticulum (ER) activates the Unfolded Protein Response (UPR ER ) to restore ER homeostasis. The AAA +…”
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