Search Results - "TAO, QIUSHAN"
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The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer's Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability
Published in Annals of neurology (01-12-2024)“…Sex differences in the association between cardiovascular risk factors and the incident all-cause dementia and the subtype Alzheimer's disease (AD) risk are…”
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Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers
Published in JAMA network open (05-10-2018)“…The association between peripheral inflammatory biomarkers and Alzheimer disease (AD) is not consistent in the literature. It is possible that chronic…”
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Comparison of Commonly Measured Plasma and Cerebrospinal Fluid Proteins and Their Significance for the Characterization of Cognitive Impairment Status
Published in Journal of Alzheimer's disease (01-01-2024)“…Although cerebrospinal fluid (CSF) amyloid-β42 peptide (Aβ42) and phosphorylated tau (p-tau) and blood p-tau are valuable for differential diagnosis of…”
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Association Between Elevated Depressive Symptoms and Cognitive Function Moderated by APOE4 Status: Framingham Offspring Study
Published in Journal of Alzheimer's disease (01-01-2021)“…Depression and Apolipoprotein E4 (APOE4) are associated with decreased cognitive function and differences in brain structure. This study investigated whether…”
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Cerebral Microbleeds in Different Brain Regions and Their Associations With the Digital Clock-Drawing Test: Secondary Analysis of the Framingham Heart Study
Published in Journal of medical Internet research (29-07-2024)“…Cerebral microbleeds (CMB) increase the risk for Alzheimer disease. Current neuroimaging methods that are used to detect CMB are costly and not always…”
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Monomeric C‐reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype‐dependent pattern: A risk factor for Alzheimer’s disease?
Published in Aging cell (01-11-2021)“…In chronic peripheral inflammation, endothelia in brain capillary beds could play a role for the apolipoprotein E4 (ApoE4)‐mediated risk for Alzheimer's…”
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Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease
Published in Neuropharmacology (01-06-2017)“…Amylin is an important gut-brain axis hormone. Since amylin and amyloid-β peptide (Aβ) share similar β sheet secondary structure despite not having the same…”
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The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer’s disease
Published in Translational psychiatry (22-12-2022)“…Apolipoprotein ε4 ( APOE ε4) is the most significant genetic risk factor for late-onset Alzheimer’s disease (AD). Elevated blood C-reactive protein (CRP)…”
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Comparisons of different metabolic syndrome definitions and associations with coronary heart disease, stroke, and peripheral arterial disease in a rural Chinese population
Published in PloS one (11-05-2015)“…We estimated the prevalence of metabolic syndrome (MetS) and compared associations of different MetS definitions with coronary heart disease (CHD), stroke, and…”
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An accurate risk score for estimation 5-year risk of type 2 diabetes based on a health screening population in Taiwan
Published in Diabetes research and clinical practice (01-08-2009)“…Abstract This study aimed to provide the epidemiological model evaluating the risk of developing type 2 diabetes (T2DM) in Taiwan periodic health-check…”
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educational level, obesity and incidence of diabetes among Chinese adult men and women aged 18-59 years old: an 11-year follow-up study
Published in PloS one (20-06-2013)“…To determine whether educational level and overweight/obesity was associated with the development of diabetes among Chinese adult men and women. A cohort…”
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Risk prediction model of dyslipidaemia over a 5-year period based on the Taiwan MJ health check-up longitudinal database
Published in Lipids in health and disease (17-11-2018)“…This study aimed to provide an epidemiological model to evaluate the risk of developing dyslipidaemia within 5 years in the Taiwanese population. A cohort of…”
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Pramlintide: The Effects of a Single Drug Injection on Blood Phosphatidylcholine Profile for Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2018)“…Studies suggest that a single injection of pramlintide, an amylin analog, induces changes in Alzheimer's disease (AD) biomarkers in the blood of AD mouse…”
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Metabolic syndrome and the development of chronic kidney disease among 118 924 non-diabetic Taiwanese in a retrospective cohort
Published in Nephrology (Carlton, Vic.) (01-02-2010)“…Aim: Metabolic syndrome (MetS) is a common risk factor for cardiovascular and chronic kidney disease (CKD) in Western populations; however, no prospective…”
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Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study
Published in EClinicalMedicine (01-11-2022)“…It remains unclear whether persistent loneliness is related to brain structures that are associated with cognitive decline and development of Alzheimer's…”
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Monomeric C‐reactive protein induces the cellular pathology of Alzheimer's disease
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)“…Introduction Human study shows that elevated C‐reactive protein (CRP) in blood impacts apolipoprotein E (APOE) ε4, but not APOE ε3 or APOE ε2, genotype to…”
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Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults
Published in JAMA network open (02-08-2019)“…Preclinical studies suggest that amylin has a U-shaped dose-response association with risk of Alzheimer disease (AD). The association of plasma amylin with AD…”
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Identification of an APOE ε4–specific blood‐based molecular pathway for Alzheimer's disease risk
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-10-2023)“…INTRODUCTION The precise apolipoprotein E (APOE) ε4‐specific molecular pathway(s) for Alzheimer's disease (AD) risk are unclear. METHODS Plasma protein…”
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Uric acid and incident chronic kidney disease in a large health check-up population in Taiwan
Published in Nephrology (Carlton, Vic.) (01-11-2011)“…ABSTRACT Aim: Uric acid (UA) is strongly associated with the confirmed chronic kidney disease (CKD) risk factors, such as hypertension, diabetes and metabolic…”
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The association between circulating CD34+CD133+ endothelial progenitor cells and reduced risk of Alzheimer's disease in the Framingham Heart Study
Published in Exploration of medicine (2024)“…Endothelial dysfunction has been associated with both cerebrovascular pathology and Alzheimer's disease (AD). However, the connection between circulating…”
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