Search Results - "TANZARELLA, Silvia"
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Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine
Published in Cancer research (Chicago, Ill.) (15-12-2004)“…Cancer/testis antigens (CTA) are suitable targets for immunotherapy of human malignancies, and clinical trials are mainly focusing on MAGE-A3. However, the…”
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Dendritic Cells Acquire the MAGE-3 Human Tumor Antigen from Apoptotic Cells and Induce a Class I-Restricted T Cell Response
Published in Proceedings of the National Academy of Sciences - PNAS (29-02-2000)“…In an attempt to transduce monocyte-derived dendritic cells (DCs) with a retroviral vector coding for an intracytoplasmic tumor antigen (TAA), we were…”
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Identification of a promiscuous T-cell epitope encoded by multiple members of the MAGE family
Published in Cancer research (Chicago, Ill.) (01-06-1999)“…One of the major limitations of tumor-specific vaccination is the generation of antigen-loss variants that are able to escape the immune response elicited by a…”
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Rhabdomyosarcomas are potential target of MAGE-specific immunotherapies
Published in Cancer Immunology, Immunotherapy (01-06-2004)“…The search for alternative strategies of therapy remains a major issue for most neoplastic diseases. The expression of several tumor antigens makes human…”
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Multiple HLA-A alleles can present an immunodominant peptide of the human melanoma antigen Melan-A/MART-1 to a peptide-specific HLA-A0201+ cytotoxic T cell line
Published in The Journal of immunology (1950) (15-07-1996)“…The majority of HLA-A*0201-restricted tumor-infiltrating lymphocytes from melanoma patients recognize a peptide, MT(27-35), derived from the Melan-A/MART-1 Ag…”
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Functional heterogeneity of HLA-A02 subtypes revealed by presentation of a MAGE-3-encoded peptide to cytotoxic T cell clones
Published in The Journal of immunology (1950) (01-09-1997)“…The peptide-binding and presentation characteristics of seven naturally occurring HLA-A2 subtypes were studied using M3(271), a peptide derived from the…”
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Rexpression of HLA class I antigens and restoration of antigen‐specific CTL response in melanoma cells following 5‐aza‐2′‐deoxycytidine treatment
Published in International journal of cancer (15-10-2001)“…Cell surface expression of HLA class I/peptide complexes on tumor cells is a key step in the generation of T‐cell‐based immune responses. Several genetic…”
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Characterization of antigenic peptides presented by HLA‐B44 molecules on tumor cells expressing the gene MAGE‐3
Published in International journal of cancer (27-11-1996)“…The amino acid sequence of the protein encoded by the gene MAGE‐3was screened for peptides containing the binding motif for HLA‐B44. Nine peptides were…”
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Characterization of antigenic peptides presented by HLA-B44 molecules on tumor cells expressing the geneMAGE-3
Published in International journal of cancer (27-11-1996)Get full text
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