Search Results - "TANIERE, Philippe"

KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer by Lal, Neeraj, White, Brian S, Goussous, Ghaleb, Pickles, Oliver, Mason, Mike J, Beggs, Andrew D, Taniere, Philippe, Willcox, Benjamin E, Guinney, Justin, Middleton, Gary W

“…mutation is a common canonical mutation in colorectal cancer, found at differing frequencies in all consensus molecular subtypes (CMS). The independent…”
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The Clinicopathological and Molecular Associations of PD-L1 Expression in Non-small Cell Lung Cancer: Analysis of a Series of 10,005 Cases Tested with the 22C3 Assay by Evans, Matthew, O’Sullivan, Brendan, Hughes, Frances, Mullis, Tina, Smith, Matthew, Trim, Nicola, Taniere, Philippe

“…PD-L1 expression testing is mandatory prior to pembrolizumab prescription in non-small cell lung cancer. Our service offers PD-L1 testing using the PD-L1 IHC…”
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PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains by PICAUD, Sarah, DA COSTA, David, BRADNER, James E, TANIERE, Philippe, O'SULLIVAN, Brendan, MÜLLER, Susanne, SCHWALLER, Juerg, STANKOVIC, Tatjana, KNAPP, Stefan, THANASOPOULOU, Angeliki, FILIPPAKOPOULOS, Panagis, FISH, Paul V, PHILPOTT, Martin, FEDOROV, Oleg, BRENNAN, Paul, BUNNAGE, Mark E, OWEN, Dafydd R

“…Bromo and extra terminal (BET) proteins (BRD2, BRD3, BRD4, and BRDT) are transcriptional regulators required for efficient expression of several growth…”
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Squamous Cell Carcinoma in Never Smokers: An Insight into SMARCB1 Loss by Patel, Akshay J, Hemead, Hanan, Jesani, Hannah, Bille, Andrea, Taniere, Philippe, Middleton, Gary

“…Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) constituting 85% of cases. Among NSCLCs,…”
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Genomic complexity of urothelial bladder cancer revealed in urinary cfDNA by Togneri, Fiona S, Ward, Douglas G, Foster, Joseph M, Devall, Adam J, Wojtowicz, Paula, Alyas, Sofia, Vasques, Fabiana Ramos, Oumie, Assa, James, Nicholas D, Cheng, K K, Zeegers, Maurice P, Deshmukh, Nayneeta, O'Sullivan, Brendan, Taniere, Philippe, Spink, Karen G, McMullan, Dominic J, Griffiths, Mike, Bryan, Richard T

“…Urothelial bladder cancers (UBCs) have heterogeneous clinical characteristics that are mirrored in their diverse genomic profiles. Genomic profiling of UBCs…”
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A novel next generation sequencing approach to improve sarcoma diagnosis by McConnell, Lauren, Houghton, Oisín, Stewart, Peter, Gazdova, Jana, Srivastava, Shambhavi, Kim, Chang, Catherwood, Mark, Strobl, Anna, Flanagan, Adrienne M., Oniscu, Anca, Kroeze, Leonie I., Groenen, Patricia, Taniere, Philippe, Salto-Tellez, Manuel, Gonzalez, David

“…Sarcoma is a rare disease affecting both bone and connective tissue and with over 100 pathologic entities, differential diagnosis can be difficult…”
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Large-Scale EGFR Mutation Testing in Clinical Practice: Analysis of a Series of 18,920 Non-Small Cell Lung Cancer Cases by Evans, Matthew, O’Sullivan, Brendan, Smith, Matthew, Hughes, Frances, Mullis, Tina, Trim, Nicola, Taniere, Philippe

“…We make use of a very large dataset of non-small cell lung cancer specimens to examine the molecular epidemiology of EGFR mutations, particularly with respect…”
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Adenoid cystic carcinoma of the thymus gland by Shatila, Mohamed, Hemead, Hanan, Murukesh, Nishanth, Taniere, Philippe, Russell, Caroline, Menon, Ashvini, Patel, Akshay J

“…Abstract Background Thymic carcinomas are rare and aggressive tumours. They constitute a heterogeneous group of tumours with various histological patterns and…”
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PD-L1 Testing in Urothelial Carcinoma: Analysis of a Series of 1401 Cases Using Both the 22C3 and SP142 Assays by Evans, Harriet, O'Sullivan, Brendan, Hughes, Frances, Charles, Kathryn, Robertson, Lee, Taniere, Philippe, Diaz-Cano, Salvador

“…Immune checkpoint blockade (ICB) drugs are a novel, effective treatment for advanced urothelial carcinoma. Worldwide, several different ICB drugs are approved,…”
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TMP3-NTRK1 rearranged uterine sarcoma: A case report by Boyle, William, Williams, Anthony, Sundar, Sudha, Yap, Jason, Taniere, Philippe, Rehal, Pauline, Ganesan, Raji

“…Uterine sarcomas are a group of rare tumours with heterogeneous morphological and genetic features. Recent advances in the molecular characterisation of these…”
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Pulmonary-type adenocarcinoma and signet ring mucinous adenocarcinoma arising in an ovarian dermoid cyst: report of a unique case by Boyd, Clinton, FRCPath, Patel, Kaushik, FRCPath, O'Sullivan, Brendan, FRCPath, Taniere, Philippe, FRCPath, McCluggage, W. Glenn, FRCPath

“…Summary Dermoid cysts are common benign ovarian germ cell neoplasms. Occasionally, one of the mature elements undergoes malignant transformation resulting in…”
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Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas by Ng, Alvin Wei Tian, Contino, Gianmarco, Killcoyne, Sarah, Devonshire, Ginny, Hsu, Ray, Abbas, Sujath, Su, Jing, Redmond, Aisling M., Weaver, Jamie M. J., Eldridge, Matthew D., Tavaré, Simon, Edwards, Paul A. W., Fitzgerald, Rebecca C.

“…Oesophageal adenocarcinoma (OAC) provides an ideal case study to characterize large-scale rearrangements. Using whole genome short-read sequencing of 383…”
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KIT Mutation and Loss of 14q May Be Sufficient for the Development of Clinically Symptomatic Very Low-Risk GIST by Klinke, Olaf Karl, Mizani, Tuba, Baldwin, Gouri, Bancel, Brigitte, Devouassoux-Shisheboran, Mojgan, Scoazec, Jean-Yves, Bringuier, Pierre-Paul, Feederle, Regina, Jauch, Anna, Hinderhofer, Katrin, Taniere, Philippe, Delecluse, Henri-Jacques

“…The aim of this study was to determine the minimal set of genetic alterations required for the development of a very low risk clinically symptomatic…”
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Enhanced neoplasia detection in chronic ulcerative colitis: the ENDCaP-C diagnostic accuracy study by Awasthi, Ashish, Barbour, Jamie, Beggs, Andrew, Bhandari, Pradeep, Blakeway, Daniel, Brookes, Matthew, Brown, James, Brown, Matthew, Caldwell, Germaine, Clokie, Samuel, Colleypriest, Ben, Conlin, Abby, de Silva, Shanika, de Caestecker, John, Deeks, Jonathan, Dhar, Anjan, Dilworth, Mark, Fogden, Edward, Foley, Stephen, Ghosh, Deb, Grellier, Leonie, Hart, Ailsa, Hoque, Syed Samiul, Iacucci, Marietta, Iqbal, Tariq, James, Jonathan, Jarvis, Mark, Jayaprakash, Anthoor, Keshav, Satish, Magill, Laura, Matthews, Glenn, Mawdsley, Joel, McLaughlin, Simon, Mehta, Samir, Monahan, Kevin, Morton, Dion, Murugesan, Senthil, Parkes, Miles, Pestinger, Valerie, Probert, Chris, Ramadas, Arvind, Rettino, Alessandro, Sebastian, Shaji, Sharma, Naveen, Griffiths, Michael, Stockton, Joanne, Subramanian, Venkat, Suggett, Nigel, Taniere, Philippe, Teare, Julian, Verma, Ajay M, Wallis, Yvonne

“…Background Chronic ulcerative colitis is a large bowel inflammatory condition associated with increased colorectal cancer risk over time, resulting in 1000…”
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Impact of tissue processing, archiving and enrichment techniques on DNA methylation yield in rectal carcinoma by Leong, Kai Juen, James, Jonathan, Wen, Kaisheng, Taniere, Philippe, Morton, Dion G., Bach, Simon P., Matthews, Glenn M.

“…Formalin fixation, duration of tissue storage and tissue enrichment techniques can affect DNA methylation yield but these effects have not been quantitatively…”
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Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1 by Alabraba, Edward, Bramhall, Simon, O'Sullivan, Brendan, Mahon, Brinder, Taniere, Philippe

“…Gastrointestinal stromal tumours (GIST) frequently occur in patients with neurofibromatosis type 1 (NF-1). It has been reported that GIST may co-exist with…”
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Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran by SEPEHR, Alireza, TANIERE, Philippe, MARTEL-PLANCHE, Ghislaine, ZIA'EE, Abed-Ali, RASTGAR-JAZII, Ferdous, YAZDANBOD, Mansour, ETEMAD-MOGHADAM, Gholamreza, KAMANGAR, Farin, SAIDI, Farrokh, HAINAUT, Pierre

“…Extremely high rates of squamous cell carcinoma of the esophagus (SCCE) are observed in Iran, reflecting unknown, genetic and/or epidemiological risk factors…”
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Tp53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke : Distinct patterns in never, former, and current smokers by LE CALVEZ, Florence, MUKERIA, Anush, HUNT, Jay D, KELM, Olaf, HUNG, Rayjean J, TANIERE, Philippe, BRENNAN, Paul, BOFFETTA, Paolo, ZARIDZE, David G, HAINAUT, Pierre

“…TP53 mutations are common in lung cancers of smokers, with high prevalence of G:C-to-T:A transversions generally interpreted as mutagen fingerprints of tobacco…”
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Predicting programmed death-ligand 1 (PD-L1) expression with fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) metabolic parameters in resectable non-small cell lung cancer by Hughes, Daniel Johnathan, Josephides, Eleni, O’Shea, Robert, Manickavasagar, Thubeena, Horst, Carolyn, Hunter, Sarah, Tanière, Philippe, Nonaka, Daisuke, Van Hemelrijck, Mieke, Spicer, James, Goh, Vicky, Bille, Andrea, Karapanagiotou, Eleni, Cook, Gary J. R.

“…Background Programmed death-ligand 1 (PD-L1) expression is a predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). PD-L1 and glucose…”
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Expression and functional consequences of oestrogen and progesterone receptors in human insulinomas by Alabraba, Edward B, Taniere, Philippe, Reynolds, Gary M, Stewart, Paul M, Wigmore, Stephen J, Bramhall, Simon R

“…The expression of steroid receptors by tumours offers a therapeutic advantage if functionally responsive to exogenous hormones. Insulinomas represent a highly…”
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