Search Results - "TANGSOMBATVISIT, Stephanie"

On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions by Price, Jordan V, Tangsombatvisit, Stephanie, Xu, Guangyu, Yu, Jiangtao, Levy, Dan, Baechler, Emily C, Gozani, Or, Varma, Madoo, Utz, Paul J, Liu, Chih Long

“…Using the semiconductor synthesis technology of maskless photolithography on microprocessor-grade silicon wafers, Jordan Price and colleagues synthesized…”
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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies by Liu, Chih Long, Tangsombatvisit, Stephanie, Rosenberg, Jacob M, Mandelbaum, Gil, Gillespie, Emily C, Gozani, Or P, Alizadeh, Ash A, Utz, Paul J

“…Autoreactivity to histones is a pervasive feature of several human autoimmune disorders, including systemic lupus erythematosus (SLE). Specific…”
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Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance by Revelo, Xavier S., Ghazarian, Magar, Chng, Melissa Hui Yen, Luck, Helen, Kim, Justin H., Zeng, Kejing, Shi, Sally Y., Tsai, Sue, Lei, Helena, Kenkel, Justin, Liu, Chih Long, Tangsombatvisit, Stephanie, Tsui, Hubert, Sima, Corneliu, Xiao, Changting, Shen, Lei, Li, Xiaoying, Jin, Tianru, Lewis, Gary F., Woo, Minna, Utz, Paul J., Glogauer, Michael, Engleman, Edgar, Winer, Shawn, Winer, Daniel A.

“…Obesity-related inflammation of metabolic tissues, including visceral adipose tissue (VAT) and liver, are key factors in the development of insulin resistance…”
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Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape by WOO, Seng-Ryong, TURNIS, Meghan E, TANGSOMBATVISIT, Stephanie, GROSSO, Joseph F, NETTO, George, SMELTZER, Matthew P, CHAUX, Alcides, UTZ, Paul J, WORKMAN, Creg J, PARDOLL, Drew M, KORMAN, Alan J, DRAKE, Charles G, GOLDBERG, Monica V, VIGNALI, Dario A. A, BANKOTI, Jaishree, SELBY, Mark, NIRSCHL, Christopher J, BETTINI, Matthew L, GRAVANO, David M, VOGEL, Peter, LONG LIU, Chih

“…Inhibitory receptors on immune cells are pivotal regulators of immune escape in cancer. Among these inhibitory receptors, CTLA-4 (targeted clinically by…”
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Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range by Tabakman, Scott M., Lau, Lana, Robinson, Joshua T., Price, Jordan, Sherlock, Sarah P., Wang, Hailiang, Zhang, Bo, Chen, Zhuo, Tangsombatvisit, Stephanie, Jarrell, Justin A., Utz, Paul J., Dai, Hongjie

“…Protein chips are widely used for high-throughput proteomic analysis, but to date, the low sensitivity and narrow dynamic range have limited their capabilities…”
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C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes by Santer, Deanna M, Hall, Brian E, George, Thaddeus C, Tangsombatvisit, Stephanie, Liu, Chih Long, Arkwright, Peter D, Elkon, Keith B

“…Almost all humans with homozygous deficiency of C1q develop systemic lupus erythematosus (SLE). The precise cellular mechanism(s) by which C1q prevents the…”
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Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling by Gozani, Or, Levy, Dan, Kuo, Alex J, Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M, Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I, Kuo, Andrew Y, Tanjing, Song, Cheung, Regina, Chua, Katrin F, Utz, Paul J, Shi, Xiaobing, Prinjha, Rab K, Lee, Kevin, Garcia, Benjamin A, Bedford, Mark T, Tarakhovsky, Alexander, Cheng, Xiaodong

“…Binding of the transcription factor NF-κB subunit RelA activates proinflammatory gene expression. Gozani and colleagues show that basal expression of RelA…”
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Development of Th17-associated interstitial kidney inflammation in lupus-prone mice lacking the gene encoding Signal Transduction and Activator of Transcription-1 (STAT-1) by Yiu, Gloria, Rasmussen, Tue Kruse, Ajami, Bahareh, Haddon, David J., Chu, Alvina D., Tangsombatvisit, Stephanie, Haynes, Winston A., Diep, Vivian, Steinman, Larry, Faix, James, Utz, Paul J.

“…Type I interferon (IFN-I) signaling is a central pathogenic pathway in Systemic Lupus Erythematosus (SLE), and therapeutics targeting IFN-I signaling are in…”
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Development of Th17‐Associated Interstitial Kidney Inflammation in Lupus‐Prone Mice Lacking the Gene Encoding STAT‐1 by Yiu, Gloria, Rasmussen, Tue K., Ajami, Bahareh, Haddon, David J., Chu, Alvina D., Tangsombatvisit, Stephanie, Haynes, Winston A., Diep, Vivian, Steinman, Larry, Faix, James, Utz, Paul J.

“…Objective Type I interferon (IFN) signaling is a central pathogenic pathway in systemic lupus erythematosus (SLE), and therapeutics targeting type I IFN…”
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Silicon-based peptide microarrays for epitope mapping of serum autoantibodies from patients with systemic lupus erythematosus with single-amino acid resolution (P4030) by Haddon, David, Jarrell, Justin, Liu, Chih-Long, Price, Jordan, Tangsombatvisit, Stephanie, Credo, Grace, Xu, Guangyu, Varma, Madoo, Baechler, Emily, Utz, Paul

“…Abstract We have developed a silicon-based peptide microarray with >5,700 features, corresponding to 891 unique peptides derived from the U1-70 protein, a…”
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Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution by Haddon, David James, Jarrell, Justin Ansel, Diep, Vivian K., Wand, Hannah E., Price, Jordan V., Tangsombatvisit, Stephanie, Credo, Grace M., Mackey, Sally, Dekker, Cornelia L., Baechler, Emily C., Liu, Chih Long, Varma, Madoo, Utz, Paul J.

“…The mechanisms underlying development of ribonucleoprotein (RNP) autoantibodies are unclear. The U1-70K protein is the predominant target of RNP…”
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Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies by Liu, Chih L, Tangsombatvisit, Stephanie, Rosenberg, Jacob M, Mandelbaum, Gil, Gillespie, Emily C, Gozani, Or P, Alizadeh, Ash A, Utz, Paul J

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Lysine methylation of the NF-[kappa]B subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-[kappa]B signaling by Levy, Dan, Kuo, Alex J, Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M, Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I, Kuo, Andrew Y, Tanjing, Song, Cheung, Regina, Chua, Katrin F, Utz, Paul J, Shi, Xiaobing, Prinjha, Rab K, Lee, Kevin, Garcia, Benjamin A, Bedford, Mark T, Tarakhovsky, Alexander, Cheng, Xiaodong, Gozani, Or

“…Signaling via the methylation of lysine residues in proteins has been linked to diverse biological and disease processes, yet the catalytic activity and…”
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SETD6 lysine methylation of RelA couples GLP activity at chromatin to tonic repression of NF-κB signaling by Levy, Dan, Kuo, Alex J., Chang, Yanqi, Schaefer, Uwe, Kitson, Christopher, Cheung, Peggie, Espejo, Alexsandra, Zee, Barry M., Liu, Chih Long, Tangsombatvisit, Stephanie, Tennen, Ruth I., Kuo, Andrew Y., Tanjing, Song, Cheung, Regina, Chua, Katrin F., Utz, Paul J., Shi, Xiaobing, Prinjha, Rab K., Lee, Kevin, Garcia, Benjamin A., Bedford, Mark T., Tarakhovsky, Alexander, Cheng, Xiaodong, Gozani, Or

“…Protein lysine methylation signaling is implicated in diverse biological and disease processes. Yet the catalytic activity and substrate specificity are…”
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