Search Results - "TANGHETTI, EMIL A."

Dermal sensitization, safety, and tolerability of triple-combination clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel from three clinical trials by Draelos, Zoe D., Tanghetti, Emil A., Kircik, Leon H., Bhatia, Neal, Zeichner, Joshua A., Sugarman, Jeffrey L., Stein Gold, Linda

“…Using a three-pronged acne treatment approach-combining an antibiotic, antimicrobial agent, and retinoid-may provide greater efficacy than monad or dyad…”
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Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin by Tanghetti, Emil A., Zeichner, Joshua A., Gold, Michael, Sadick, Neil, Cook-Bolden, Fran E., Kircik, Leon H., Stein Gold, Linda, Weiss, Jonathan, Tyring, Stephen K., Del Rosso, James Q., Guenin, Eric

“…Excessive sebum production is a factor in acne development. Tazarotene 0.045% lotion has demonstrated reductions in acne lesions and acne-induced sequelae…”
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The histology of skin treated with a picosecond alexandrite laser and a fractional lens array by Tanghetti, Emil A.

“…Background and Objectives The treatment of acne scars and wrinkles with a picosecond Alexandrite laser was recently FDA cleared. In 2014 we presented our…”
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A Current Review of Topical Benzoyl Peroxide: New Perspectives on Formulation and Utilization by Tanghetti, Emil A., MD, Popp, Karl F., RPh

“…Benzoyl peroxide (BPO) is the most widely used topical acne treatment, with significant antibacterial, antikeratolytic, and comedolytic activity. It has been…”
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Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 Analysis by Kircik, Leon H., Stein Gold, Linda, Gold, Michael, Weiss, Jonathan S., Harper, Julie C., Del Rosso, James Q., Bunick, Christopher G., Bhatia, Neal, Tanghetti, Emil A., Eichenfield, Lawrence F., Baldwin, Hilary, Draelos, Zoe D., Callender, Valerie D., Han, George, Gooderham, Melinda J., Sadick, Neil, Lupo, Mary P., Lain, Edward (Ted), Werschler, William Philip

“…Introduction A three-pronged approach to acne treatment combining an antibiotic, antimicrobial, and retinoid may be more efficacious than single/double…”
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The role of inflammation in the pathology of acne by Tanghetti, Emil A

“…The conventional perspective of acne pathogenesis holds that Propionibacterium acnes colonizes the duct of the sebaceous follicle, causing an innate immune…”
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Split‐face randomized treatment of facial telangiectasia comparing pulsed dye laser and an intense pulsed light handpiece by Tanghetti, Emil A.

“…Background and Objective Facial telangiectasia and other vascular lesions have historically been effectively treated with the pulsed dye laser (PDL). This…”
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Optimized formulation for topical application of a fixed combination halobetasol/tazarotene lotion using polymeric emulsion technology by Tanghetti, Emil A., Stein Gold, Linda, Del Rosso, James Q., Lin, Tina, Angel, Arturo, Pillai, Radhakrishnan

“…Successful clinical data on halobetasol propionate 0.01%/tazarotene 0.045% (HP/TAZ) lotion in moderate-to-severe plaque psoriasis are published. This article…”
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Challenges in Psoriatic Disease Addressed by Fixed-Combination Halobetasol Propionate 0.01% and Tazarotene 0.045% Lotion by Kircik, Leon, Tanghetti, Emil A, Friedman, Adam, Kucera, Kristine, Jacobson, Abby

“…The fixed-dose corticosteroid/retinoid combination halobetasol propionate (0.01%) and tazarotene (0.045%) lotion (HP/TAZ) is approved for topical treatment of…”
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A Phase 2, Multicenter, Double-Blind, Randomized, Vehicle-Controlled Clinical Study to Compare the Safety and Efficacy of a Novel Tazarotene 0.045% Lotion and Tazarotene 0.1% Cream in the Treatment of Moderate-to-Severe Acne Vulgaris by Tanghetti, Emil A., Kircik, Leon H., Green, Lawrence J., Guenin, Eric, Harris, Susan, Martin, Gina, Pillai, Radhakrishnan

“…Background: Tazarotene has been extensively studied in clinical trials and is widely used to treat acne vulgaris (acne). Irritation potential has limited its…”
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Oxymetazoline and Energy‐Based Therapy in Patients with Rosacea: Evaluation of the Safety and Tolerability in an Open‐Label, Interventional Study by Tanghetti, Emil A., Goldberg, David J., Dover, Jeffrey S., Geronemus, Roy G., Bai, Zane, Alvandi, Nancy, Shanler, Stuart D.

“…Background and Objectives The objectives of this study were to evaluate the safety, tolerability, and efficacy of oxymetazoline hydrochloride cream, 1%…”
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Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug by Stein Gold, Linda, Baldwin, Hilary, Kircik, Leon H., Weiss, Jonathan S., Pariser, David M., Callender, Valerie, Lain, Edward, Gold, Michael, Beer, Kenneth, Draelos, Zoe, Sadick, Neil, Pillai, Radhakrishnan, Bhatt, Varsha, Tanghetti, Emil A.

“…Background A three-pronged approach to acne treatment—combining an antibiotic, antibacterial, and retinoid—could provide greater efficacy and tolerability than…”
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A Controlled Comparison Study of Topical Fluourouracil 5% Cream Pre-Treatment of Aminolevulinic Acid/Photodynamic Therapy for Actinic Keratosis by Tanghetti, Emil A, Hamann, Carolyn, Tanghetti, Margo

“…Topical Fluorouracil 5% cream (5-FU) and 20% aminolevulinic acid (ALA)/ photodynamic therapy (PDT) are both FDA approved for the treatment of Actinic Keratosis…”
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Comparison of the Cutaneous Thermal Signatures Over Twenty-Four Hours With a Picosecond Alexandrite Laser Using a Flat or Fractional Optic by Tanghetti, Emil A, Tartar, Danielle M

“…This study explored immediate heat signatures with different passing techniques and the delayed thermal data points with the picosecond Alexandrite laser with…”
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Novel Polymeric Lotion Formulation of Once-Daily Tazarotene (0.045%) for Moderate-to-Severe Acne: Pooled Phase 3 Analysis by Tanghetti, Emil A, Werschler, William Philip, Lain, Edward, Guenin, Eric, Harris, Susan, Loncaric, Anya, Pillai, Radhakrishnan

“…Background: As current tazarotene formulations indicated for acne (0.1%) can cause irritation, a new tazarotene 0.045% lotion formu-lation was developed using…”
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Triple‐combination clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel for moderate‐to‐severe acne in children and adolescents: Randomized phase 2 study by Eichenfield, Lawrence F., Stein Gold, Linda, Kircik, Leon H., Werschler, William P., Beer, Kenneth, Draelos, Zoe D., Tanghetti, Emil A., Papp, Kim A., Baldwin, Hilary, Lain, Edward, Sadick, Neil, Gooderham, Melinda J., Konda, Adarsh

“…Background/Objectives Topical clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel (IDP‐126) is the first fixed‐dose triple‐combination…”
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Safety and Efficacy of a Fixed Combination Halobetasol and Tazarotene Lotion in the Treatment of Moderate-to-Severe Plaque Psoriasis: A Pooled Analysis of Two Phase 3 Studies by Sugarman, Jeffrey L, Weiss, Jonathan, Tanghetti, Emil A, Bagel, Jerry, Yamauchi, Paul S, Stein Gold, Linda, Lin, Tina, Martin, Gina, Pillai, Radhakrishnan, Israel, Robert

“…Topical corticosteroids (TCS) are the mainstay of psoriasis treatment. Safety concerns may limit use. Combination with tazarotene may optimize efficacy and…”
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Rosacea Core Domain Set for Clinical Trials and Practice: A Consensus Statement by Dirr, McKenzie A, Ahmed, Areeba, Schlessinger, Daniel I, Haq, Misha, Shi, Victoria, Koza, Eric, Ma, Melissa, Christensen, Rachel E, Ibrahim, Sarah A, Schmitt, Jochen, Johannsen, Lena, Asai, Yuka, Baldwin, Hilary E, Berardesca, Enzo, Berman, Brian, Vieira, Ana Carolina, Chien, Anna L, Cohen, David E, Del Rosso, James Q, Dosal, Jacquelyn, Drake, Lynn A, Feldman, Steven R, Fleischer, Jr, Alan B, Friedman, Adam, Graber, Emmy, Harper, Julie C, Helfrich, Yolanda R, Jemec, Gregor B, Johnson, Sandra M, Katta, Rajani, Lio, Peter, Maier, Lisa E, Martin, George, Nagler, Arielle R, Neuhaus, Isaac M, Palamar, Melis, Parish, Lawrence C, Rosen, Theodore, Shumack, Stephen P, Solomon, James A, Tanghetti, Emil A, Webster, Guy F, Weinkle, Allison, Weiss, Jonathan S, Wladis, Edward J, Maher, Ian A, Sobanko, Joseph F, Cartee, Todd V, Cahn, Brian A, Alam, Murad, Kang, Bianca Y, Iyengar, Sanjana, Anvery, Noor, Alpsoy, Erkan, Bewley, Anthony, Dessinioti, Clio, Egeberg, Alexander, Engin, Burhan, Gollnick, Harald P M, Ioannides, Dimitrios, Kim, Hei Sung, Lazaridou, Elizabeth, Li, Ji, Lim, Hester Gail, Micali, Giuseppe, de Oliveira, Clivia Maria Moraes, Noguera-Morel, Lucero, Parodi, Aurora, Reinholz, Markus, Suh, Dae Hun, Sun, Qiuning, van Zuuren, Esther J, Wollina, Uwe, Zhou, Youwen, Zip, Catherine, Poon, Emily, Pearlman, Ross

“…Inconsistent reporting of outcomes in clinical trials of rosacea is impeding and likely preventing accurate data pooling and meta-analyses. There is a need for…”
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New Polymeric Once-Daily Tazarotene 0.045% Lotion Formulation for Moderate-to-Severe Acne: Pooled Phase 3 Pediatric Analysis by Eichenfield, Lawrence F, Tanghetti, Emil A, Guenin, Eric, Martin, Gina, Pillai, Radhakrishnan

“…Acne vulgaris affects approximately 85% of adolescents. Topical tazarotene is efficacious and safe for acne treatment but irritation limits its use. The…”
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A Randomized, Double-Blind Trial to Investigate the Equivalence of IncobotulinumtoxinA and OnabotulinumtoxinA for Glabellar Frown Lines by Kane, Michael A C, Gold, Michael H, Coleman, William P, Jones, Derek H, Tanghetti, Emil A, Alster, Tina S, Rohrer, Tom E, Burgess, Cheryl M, Shamban, Ava T, Finn, Eleanor

“…BACKGROUNDIncobotulinumtoxinA and onabotulinumtoxinA are indicated for the temporary improvement in the appearance of glabellar frown lines (GFL). This is the…”
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