Search Results - "TANG, Wilson"

Gut Microbiota in Cardiovascular Health and Disease by Tang, W.H Wilson, Kitai, Takeshi, Hazen, Stanley L

“…Significant interest in recent years has focused on gut microbiota–host interaction because accumulating evidence has revealed that intestinal microbiota play…”
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Dietary metabolism, the gut microbiome, and heart failure by Tang, W. H. Wilson, Li, Daniel Y., Hazen, Stanley L.

“…Advances in our understanding of how the gut microbiota contributes to human health and diseases have expanded our insight into how microbial composition and…”
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The contributory role of gut microbiota in cardiovascular disease by Tang, W H Wilson, Hazen, Stanley L

“…Our group recently discovered that certain dietary nutrients possessing a trimethylamine (TMA) moiety, namely choline/phosphatidylcholine and L-carnitine,…”
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Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney Disease by Tang, W.H Wilson, Wang, Zeneng, Kennedy, David J, Wu, Yuping, Buffa, Jennifer A, Agatisa-Boyle, Brendan, Li, Xinmin S, Levison, Bruce S, Hazen, Stanley L

“…RATIONALE:Trimethylamine-N-oxide (TMAO), a gut microbial-dependent metabolite of dietary choline, phosphatidylcholine (lecithin), and L-carnitine, is elevated…”
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Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association by Rangaswami, Janani, Bhalla, Vivek, Blair, John E.A, Chang, Tara I, Costa, Salvatore, Lentine, Krista L, Lerma, Edgar V, Mezue, Kenechukwu, Molitch, Mark, Mullens, Wilfried, Ronco, Claudio, Tang, W.H Wilson, McCullough, Peter A

“…Cardiorenal syndrome encompasses a spectrum of disorders involving both the heart and kidneys in which acute or chronic dysfunction in 1 organ may induce acute…”
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Intersections Between Microbiome and Heart Failure: Revisiting the Gut Hypothesis by Nagatomo, Yuji, MD, PhD, Tang, W. H. Wilson, MD

“…Abstract Microbes play an important role in human health and disease. In the setting of heart failure (HF), substantial hemodynamic changes, such as…”
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Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review by Tang, W H Wilson, Bäckhed, Fredrik, Landmesser, Ulf, Hazen, Stanley L

“…Despite major strides in reducing cardiovascular disease (CVD) burden with modification of classic CVD risk factors, significant residual risks remain. Recent…”
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The Gut Microbiome and Its Role in Cardiovascular Diseases by Tang, W. H Wilson, Hazen, Stanley L

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Usefulness of Neutrophil-to-Lymphocyte Ratio in Risk Stratification of Patients With Advanced Heart Failure by Benites-Zapata, Vicente A., MD, Hernandez, Adrian V., MD, PhD, Nagarajan, Vijaiganesh, MD, MRCP, Cauthen, Clay A., MA, MD, Starling, Randall C., MD, MPH, Wilson Tang, W.H., MD

“…Elevated neutrophil-to-lymphocyte ratio (NLR) has been associated with increased mortality in patients with acute heart failure (HF) and neoplastic diseases…”
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Intestinal Microbiota in Cardiovascular Health and Disease by Tang, W.H. Wilson, Bäckhed, Fredrik, Landmesser, Ulf, Hazen, Stanley L.

“…Despite major strides in reducing cardiovascular disease (CVD) burden with modification of classic CVD risk factors, significant residual risks remain. Recent…”
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Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk by Tang, W.H. Wilson, Wang, Zeneng, Levison, Bruce S, Koeth, Robert A, Britt, Earl B, Fu, Xiaoming, Wu, Yuping, Hazen, Stanley L

“…The production of trimethylamine-N-oxide (TMAO) from dietary phosphatidylcholine was found to be dependent on metabolism by the intestinal microbiota…”
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Plasma Trimethylamine N -Oxide, a Gut Microbe–Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden by Senthong, Vichai, MD, Li, Xinmin S., PhD, Hudec, Timothy, BS, Coughlin, John, BS, Wu, Yuping, PhD, Levison, Bruce, PhD, Wang, Zeneng, PhD, Hazen, Stanley L., MD, PhD, Tang, W.H. Wilson, MD

“…Abstract Background Trimethylamine N -oxide (TMAO), a gut microbiota metabolite from dietary phosphatidylcholine, has mechanistic links to atherosclerotic…”
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Cardiorenal Outcomes After Slow Continuous Ultrafiltration Therapy in Refractory Patients With Advanced Decompensated Heart Failure by Patarroyo, Maria, MD, Wehbe, Edgard, MD, Hanna, Mazen, MD, Taylor, David O., MD, Starling, Randall C., MD, MPH, Demirjian, Sevag, MD, Wilson Tang, W.H., MD

“…Objectives The purpose of this study was to examine the clinical outcomes of using slow continuous ultrafiltration (SCUF) in patients with acute decompensated…”
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Gut microbiome - A potential mediator of pathogenesis in heart failure and its comorbidities: State-of-the-art review by Mamic, Petra, Chaikijurajai, Thanat, Tang, W.H. Wilson

“…Gut microbiome (GMB) has been increasingly recognized as a contributor to development and progression of heart failure (HF), immune-mediated subtypes of…”
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Importance of Venous Congestion for Worsening of Renal Function in Advanced Decompensated Heart Failure by Mullens, Wilfried, MD, Abrahams, Zuheir, MD, PhD, Francis, Gary S., MD, FACC, Sokos, George, DO, Taylor, David O., MD, FACC, Starling, Randall C., MD, MPH, FACC, Young, James B., MD, FACC, Tang, W.H. Wilson, MD, FACC

“…Objectives To determine whether venous congestion, rather than impairment of cardiac output, is primarily associated with the development of worsening renal…”
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Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease by Gupta, Nilaksh, Buffa, Jennifer A., Roberts, Adam B., Sangwan, Naseer, Skye, Sarah M., Li, Lin, Ho, Karen J., Varga, John, DiDonato, Joseph A., Tang, W.H. Wilson, Hazen, Stanley L.

“…OBJECTIVE:Gut microbial metabolism of dietary choline, a nutrient abundant in a Western diet, produces trimethylamine (TMA) and the atherothrombosis- and…”
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A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors by Nemet, Ina, Saha, Prasenjit Prasad, Gupta, Nilaksh, Zhu, Weifei, Romano, Kymberleigh A., Skye, Sarah M., Cajka, Tomas, Mohan, Maradumane L., Li, Lin, Wu, Yuping, Funabashi, Masanori, Ramer-Tait, Amanda E., Naga Prasad, Sathyamangla Venkata, Fiehn, Oliver, Rey, Federico E., Tang, W.H. Wilson, Fischbach, Michael A., DiDonato, Joseph A., Hazen, Stanley L.

“…Using untargeted metabolomics (n = 1,162 subjects), the plasma metabolite (m/z = 265.1188) phenylacetylglutamine (PAGln) was discovered and then shown in an…”
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Abdominal Contributions to Cardiorenal Dysfunction in Congestive Heart Failure by Verbrugge, Frederik H., MD, Dupont, Matthias, MD, Steels, Paul, MD, Grieten, Lars, PhD, Malbrain, Manu, MD, PhD, Tang, W.H. Wilson, MD, Mullens, Wilfried, MD, PhD

“…Current pathophysiological models of congestive heart failure unsatisfactorily explain the detrimental link between congestion and cardiorenal function…”
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Evaluation of kidney function throughout the heart failure trajectory – a position statement from the Heart Failure Association of the European Society of Cardiology by Mullens, Wilfried, Damman, Kevin, Testani, Jeffrey M., Martens, Pieter, Mueller, Christian, Lassus, Johan, Tang, W.H. Wilson, Skouri, Hadi, Verbrugge, Frederik H., Orso, Francesco, Hill, Loreena, Ural, Dilek, Lainscak, Mitcha, Rossignol, Patrick, Metra, Marco, Mebazaa, Alexandre, Seferovic, Petar, Ruschitzka, Frank, Coats, Andrew

“…Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney…”
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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk by Zhu, Weifei, Gregory, Jill C., Org, Elin, Buffa, Jennifer A., Gupta, Nilaksh, Wang, Zeneng, Li, Lin, Fu, Xiaoming, Wu, Yuping, Mehrabian, Margarete, Sartor, R. Balfour, McIntyre, Thomas M., Silverstein, Roy L., Tang, W.H. Wilson, DiDonato, Joseph A., Brown, J. Mark, Lusis, Aldons J., Hazen, Stanley L.

“…Normal platelet function is critical to blood hemostasis and maintenance of a closed circulatory system. Heightened platelet reactivity, however, is associated…”
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