Search Results - "TANG, T. Y"
-
1
Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells
Published in Nature chemistry (01-01-2022)“…Key requirements for the first cells on Earth include the ability to compartmentalize and evolve. Compartmentalization spatially localizes biomolecules from a…”
Get full text
Journal Article -
2
Reversible pH‐Responsive Coacervate Formation in Lipid Vesicles Activates Dormant Enzymatic Reactions
Published in Angewandte Chemie International Edition (06-04-2020)“…In situ, reversible coacervate formation within lipid vesicles represents a key step in the development of responsive synthetic cellular models. Herein, we…”
Get full text
Journal Article -
3
MaxSynBio: Avenues Towards Creating Cells from the Bottom Up
Published in Angewandte Chemie International Edition (08-10-2018)“…A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective…”
Get full text
Journal Article -
4
Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning
Published in Nature chemistry (01-04-2022)“…It has long been proposed that phase-separated compartments can provide a basis for the formation of cellular precursors in prebiotic environments. However, we…”
Get full text
Journal Article -
5
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model
Published in Nature chemistry (01-06-2014)“…Mechanisms of prebiotic compartmentalization are central to providing insights into how protocellular systems emerged on the early Earth. Protocell models are…”
Get full text
Journal Article -
6
In vitro gene expression within membrane-free coacervate protocells
Published in Chemical communications (Cambridge, England) (21-07-2015)“…Cell-free gene expression of a fluorescent protein (mCherry) is demonstrated within the molecularly crowded matrix of a polysaccharide/polypeptide coacervate…”
Get more information
Journal Article -
7
Enhanced Ribozyme‐Catalyzed Recombination and Oligonucleotide Assembly in Peptide‐RNA Condensates
Published in Angewandte Chemie International Edition (06-12-2021)“…The ability of RNA to catalyze RNA ligation is critical to its central role in many prebiotic model scenarios, in particular the copying of information during…”
Get full text
Journal Article -
8
Controlling Protein Nanocage Assembly with Hydrostatic Pressure
Published in Journal of the American Chemical Society (09-12-2020)“…Controlling the assembly and disassembly of nanoscale protein cages for the capture and internalization of protein or non-proteinaceous components is…”
Get full text
Journal Article -
9
Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in Water
Published in Angewandte Chemie International Edition (13-07-2015)“…We report on the formation of coacervate droplets from poly(diallyldimethylammonium chloride) with either adenosine triphosphate or carboxymethyl‐dextran using…”
Get full text
Journal Article -
10
Microfluidic formation of proteinosomes
Published in Chemical communications (Cambridge, England) (2018)“…Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets, based on bovine serum albumin and glucose oxidase conjugated…”
Get more information
Journal Article -
11
Frontiers in biomolecular condensate research
Published in Nature cell biology (01-04-2023)“…Biomolecular condensation of macromolecules is an increasingly important concept in cell biology. Indeed, research on condensates touches on multiple areas of…”
Get full text
Journal Article -
12
Can coacervation unify disparate hypotheses in the origin of cellular life?
Published in Current opinion in colloid & interface science (01-04-2021)“…Here, we review the recent progress in the characterisation and utilisation of coacervates as protocell models in the origin of life studies. We provide…”
Get full text
Journal Article -
13
Ribozyme activity modulates the physical properties of RNA-peptide coacervates
Published in eLife (16-06-2023)“…Condensed coacervate phases are now understood to be important features of modern cell biology, as well as valuable protocellular models in origin-of-life…”
Get full text
Journal Article -
14
IMPACT OF TYPHOONS ON THE OCEAN IN THE PACIFIC
Published in Bulletin of the American Meteorological Society (01-09-2014)“…Tropical cyclones (TCs) change the ocean by mixing deeper water into the surface layers, by the direct air–sea exchange of moisture and heat from the sea…”
Get full text
Journal Article -
15
Special Issue on Bottom‐Up Synthetic Biology
Published in Chembiochem : a European journal of chemical biology (15-10-2019)“…Bottom‐up synthetic biology uses both biological and artificial chemical building blocks to create biomimetic systems, including artificial cells. Existing and…”
Get full text
Journal Article -
16
Gene-Mediated Chemical Communication in Synthetic Protocell Communities
Published in ACS synthetic biology (16-02-2018)“…A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed,…”
Get full text
Journal Article -
17
Characterization of RNA content in individual phase-separated coacervate microdroplets
Published in Nature communications (12-05-2022)“…Condensates formed by complex coacervation are hypothesized to have played a crucial part during the origin-of-life. In living cells, condensation organizes…”
Get full text
Journal Article -
18
Cell Free Expression in Proteinosomes Prepared from Native Protein‐PNIPAAm Conjugates
Published in Macromolecular bioscience (01-03-2024)“…Towards the goal of building synthetic cells from the bottom‐up, the establishment of micrometer‐sized compartments that contain and support cell free…”
Get full text
Journal Article -
19
Guide Field Dependence of Energy Conversion and Magnetic Topologies in Reconnection Turbulent Outflow
Published in Geophysical research letters (16-07-2024)“…Energy conversion between the fields and the particles occurs through various physical processes within space environments. Magnetic reconnection stands out as…”
Get full text
Journal Article -
20
Role of ultrasonography in the diagnosis of temporal arteritis
Published in British journal of surgery (01-12-2010)“…Background: Temporal artery (TA) biopsy is the current standard for diagnosing temporal arteritis, but has limited sensitivity. Colour duplex ultrasonography…”
Get full text
Journal Article