Search Results - "TAMERLER, Candan"

Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides by Boone, Kyle, Wisdom, Cate, Camarda, Kyle, Spencer, Paulette, Tamerler, Candan

“…Current methods in machine learning provide approaches for solving challenging, multiple constraint design problems. While deep learning and related neural…”
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Antimicrobial peptide similarity and classification through rough set theory using physicochemical boundaries by Boone, Kyle, Camarda, Kyle, Spencer, Paulette, Tamerler, Candan

“…Antimicrobial peptides attract considerable interest as novel agents to combat infections. Their long-time potency across bacteria, viruses and fungi as part…”
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Molecular biomimetics: nanotechnology and bionanotechnology using genetically engineered peptides by Tamerler, Candan, Sarikaya, Mehmet

“…Nature provides inspiration for designing materials and systems that derive their functions from highly organized structures. Biological hard tissues are…”
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Adsorption Behavior of Linear and Cyclic Genetically Engineered Platinum Binding Peptides by Seker, Urartu Ozgur Safak, Wilson, Brandon, Dincer, Sevil, Kim, Il Won, Oren, Ersin Emre, Evans, John Spencer, Tamerler, Candan, Sarikaya, Mehmet

“…Recently, phage and cell-surface display libraries have been adapted for genetically selecting short peptides for a variety of inorganic materials. Despite the…”
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Autonomous-Strengthening Adhesive Provides Hydrolysis-Resistance and Enhanced Mechanical Properties in Wet Conditions by Ezazi, Mohammadamin, Ye, Qiang, Misra, Anil, Tamerler, Candan, Spencer, Paulette

“…The low-viscosity adhesive that is used to bond composite restorative materials to the tooth is readily damaged by acids, enzymes, and oral fluids. Bacteria…”
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Harnessing biomolecules for bioinspired dental biomaterials by Fischer, Nicholas G, Münchow, Eliseu A, Tamerler, Candan, Bottino, Marco C, Aparicio, Conrado

“…Dental clinicians have relied for centuries on traditional dental materials (polymers, ceramics, metals, and composites) to restore oral health and function to…”
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Threats to adhesive/dentin interfacial integrity and next generation bio‐enabled multifunctional adhesives by Spencer, Paulette, Ye, Qiang, Song, Linyong, Parthasarathy, Ranganathan, Boone, Kyle, Misra, Anil, Tamerler, Candan

“…Nearly 100 million of the 170 million composite and amalgam restorations placed annually in the United States are replacements for failed restorations. The…”
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Direct interaction of ligand-receptor pairs specifying stomatal patterning by Lee, Jin Suk, Kuroha, Takeshi, Hnilova, Marketa, Khatayevich, Dmitriy, Kanaoka, Masahiro M, McAbee, Jessica M, Sarikaya, Mehmet, Tamerler, Candan, Torii, Keiko U

“…Valves on the plant epidermis called stomata develop according to positional cues, which likely involve putative ligands (EPIDERMAL PATTERNING FACTORS [EPFs])…”
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Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells by Carson, Daniel, Hnilova, Marketa, Yang, Xiulan, Nemeth, Cameron L, Tsui, Jonathan H, Smith, Alec S.T, Jiao, Alex, Regnier, Michael, Murry, Charles E, Tamerler, Candan, Kim, Deok-Ho

“…Understanding the phenotypic development of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is a prerequisite to advancing regenerative…”
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Conformational Behavior of Genetically-Engineered Dodecapeptides as a Determinant of Binding Affinity for Gold by Corni, Stefano, Hnilova, Marketa, Tamerler, Candan, Sarikaya, Mehmet

“…Genetically engineered solid binding peptides, because of their unique affinity and specificity for solid materials, represent a promising molecular toolbox…”
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Engineering Interfacial Integrity with Hydrolytic-Resistant, Self-Reinforcing Dentin Adhesive by Demirel, Erhan, Korkmaz, Burak, Chang, Youngwoo, Misra, Anil, Tamerler, Candan, Spencer, Paulette

“…The leading cause of composite restoration failure is secondary caries, and although caries is a multifactorial problem, weak, damage-prone adhesives play a…”
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Engineered Peptide Repairs Defective Adhesive–Dentin Interface by Ye, Qiang, Spencer, Paulette, Yuca, Esra, Tamerler, Candan

“…Failure of dental composite restorations is primarily due to recurrent decay at the tooth–composite interface. At this interface, the adhesive and its bond…”
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Evolution of Network Structure and Mechanical Properties in Autonomous-Strengthening Dental Adhesive by Sarikaya, Rizacan, Song, Linyong, Ye, Qiang, Misra, Anil, Tamerler, Candan, Spencer, Paulette

“…The inherent degradation property of most dental resins in the mouth leads to the long-term release of degradation by-products at the adhesive/tooth interface…”
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Controlling Self-Assembly of Engineered Peptides on Graphite by Rational Mutation by So, Christopher R, Hayamizu, Yuhei, Yazici, Hilal, Gresswell, Carolyn, Khatayevich, Dmitriy, Tamerler, Candan, Sarikaya, Mehmet

“…Self-assembly of proteins on surfaces is utilized in many fields to integrate intricate biological structures and diverse functions with engineered materials…”
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Editorial: Biomaterials for chronic wound healing by Kammona, Olga, Vamvakaki, Maria, Tamerler, Candan

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Engineered Peptides Enable Biomimetic Route for Collagen Intrafibrillar Mineralization by Cloyd, Aya K, Boone, Kyle, Ye, Qiang, Snead, Malcolm L, Spencer, Paulette, Tamerler, Candan

“…Overcoming the short lifespan of current dental adhesives remains a significant clinical need. Adhesives rely on formation of the hybrid layer to adhere to…”
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Peptide-Enabled Nanocomposites Offer Biomimetic Reconstruction of Silver Diamine Fluoride-Treated Dental Tissues by Woolfolk, Sarah Kay, Cloyd, Aya Kirahm, Ye, Qiang, Boone, Kyle, Spencer, Paulette, Snead, Malcolm L, Tamerler, Candan

“…Caries is the most ubiquitous infectious disease of mankind, and early childhood caries (ECC) is the most prevalent chronic disease in children worldwide, with…”
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Molecular biomimetics: nanotechnology through biology by Sarikaya, Mehmet, Tamerler, Candan, Jen, Alex K. -Y, Schulten, Klaus, Baneyx, François

“…Proteins, through their unique and specific interactions with other macromolecules and inorganics, control structures and functions of all biological hard and…”
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Regulation of in vitro Calcium Phosphate Mineralization by Combinatorially Selected Hydroxyapatite-Binding Peptides by Gungormus, Mustafa, Fong, Hanson, Kim, Il Won, Evans, John Spencer, Tamerler, Candan, Sarikaya, Mehmet

“…We report selection and characterization of hydroxyapatite-binding heptapeptides from a peptide−phage library and demonstrate the effects of two peptides, with…”
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Integration of clinical perspective into biomimetic bioreactor design for orthopedics by Drapal, Victoria, Gamble, Jordan M., Robinson, Jennifer L., Tamerler, Candan, Arnold, Paul M., Friis, Elizabeth A.

“…The challenges to accommodate multiple tissue formation metrics in conventional bioreactors have resulted in an increased interest to explore novel bioreactor…”
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