Search Results - "TAMAYO, Rita"
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Cyclic diguanylate riboswitches control bacterial pathogenesis mechanisms
Published in PLoS pathogens (07-02-2019)“…The gram-negative Vibrio cholerae encodes two class I c-di-GMP riboswitches that respond to the ligand in opposing directions, and neither function by…”
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A genetic switch controls the production of flagella and toxins in Clostridium difficile
Published in PLoS genetics (27-03-2017)“…In the human intestinal pathogen Clostridium difficile, flagella promote adherence to intestinal epithelial cells. Flagellar gene expression also indirectly…”
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Growth in a Biofilm Induces a Hyperinfectious Phenotype in Vibrio cholerae
Published in Infection and Immunity (01-08-2010)“…Biofilm formation plays a multifaceted role in the life cycles of a wide variety of microorganisms. In the case of pathogenic Vibrio cholerae, biofilm…”
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4
Type IV Pili Promote Clostridium difficile Adherence and Persistence in a Mouse Model of Infection
Published in Infection and immunity (01-05-2018)“…Cyclic diguanylate (c-di-GMP) is a second messenger that regulates the transition from motile to sessile lifestyles in numerous bacteria and controls virulence…”
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5
Roles of cyclic diguanylate in the regulation of bacterial pathogenesis
Published in Annual review of microbiology (01-01-2007)“…Cyclic diguanylate (c-di-GMP) is a bacterial second messenger of growing recognition involved in the regulation of a number of complex physiological processes…”
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6
Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile
Published in PLoS pathogens (05-07-2022)“…The opportunistic nosocomial pathogen Clostridioides difficile exhibits phenotypic heterogeneity through phase variation, a stochastic, reversible process that…”
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Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile
Published in Journal of Bacteriology (01-07-2012)“…Clostridium difficile-associated disease is increasing in incidence and is costly to treat. Our understanding of how this organism senses its entry into the…”
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8
Enhancing bacterial survival through phenotypic heterogeneity
Published in PLoS pathogens (01-05-2020)“…Variations in the number of nucleotides within an SSR in a coding sequence may cause a frameshift mutation that creates a premature stop codon and a truncated…”
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Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile
Published in Journal of bacteriology (01-03-2015)“…Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections with symptoms ranging from mild diarrhea to fulminant colitis…”
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10
Rho factor mediates flagellum and toxin phase variation and impacts virulence in Clostridioides difficile
Published in PLoS pathogens (12-08-2020)“…The intestinal pathogen Clostridioides difficile exhibits heterogeneity in motility and toxin production. This phenotypic heterogeneity is achieved through…”
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Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of sigD
Published in Journal of Bacteriology (01-11-2013)“…The Gram-positive obligate anaerobe Clostridium difficile causes potentially fatal intestinal diseases. How this organism regulates virulence gene expression…”
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Regulation of Type IV Pili Contributes to Surface Behaviors of Historical and Epidemic Strains of Clostridium difficile
Published in Journal of bacteriology (01-02-2016)“…The intestinal pathogen Clostridium difficile is an urgent public health threat that causes antibiotic-associated diarrhea and is a leading cause of fatal…”
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13
The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
Published in Microbiome (28-01-2021)“…Prebiotic galacto-oligosaccharides (GOS) have an extensively demonstrated beneficial impact on intestinal health. In this study, we determined the impact of…”
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The Vibrio cholerae Pst2 Phosphate Transport System Is Upregulated in Biofilms and Contributes to Biofilm-Induced Hyperinfectivity
Published in Infection and Immunity (01-05-2012)“…Author's Correction ( vol. 80 , p. 4495 ) Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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15
The RNA Domain Vc1 Regulates Downstream Gene Expression in Response to Cyclic Diguanylate in Vibrio cholerae
Published in PloS one (05-02-2016)“…In many bacterial species, including the aquatic bacterium and human pathogen Vibrio cholerae, the second messenger cyclic diguanylate (c-di-GMP) modulates…”
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16
Genome-wide detection of conservative site-specific recombination in bacteria
Published in PLoS genetics (05-04-2018)“…The ability of clonal bacterial populations to generate genomic and phenotypic heterogeneity is thought to be of great importance for many commensal and…”
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17
Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence
Published in PLoS biology (28-10-2019)“…Recent work has revealed that Clostridioides difficile, a major cause of nosocomial diarrheal disease, exhibits phenotypic heterogeneity within a clonal…”
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Multiple Regulatory Mechanisms Control the Production of CmrRST, an Atypical Signal Transduction System in Clostridioides difficile
Published in mBio (22-02-2021)“…Clostridioides difficile, an intestinal pathogen and leading cause of nosocomial infection, exhibits extensive phenotypic heterogeneity through phase…”
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The EAL Domain Protein VieA Is a Cyclic Diguanylate Phosphodiesterase
Published in The Journal of biological chemistry (30-09-2005)“…The newly recognized bacterial second messenger 3′,5′-cyclic diguanylic acid (cyclic diguanylate (c-di-GMP)) has been shown to regulate a wide variety of…”
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PilZ Domain Proteins Bind Cyclic Diguanylate and Regulate Diverse Processes in Vibrio cholerae
Published in The Journal of biological chemistry (27-04-2007)“…Cyclic diguanylate (c-di-GMP) is an allosteric activator and second messenger implicated in the regulation of a variety of biological processes in diverse…”
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