Search Results - "TAKEUCHI, Ayako"

Spatial and Functional Crosstalk between the Mitochondrial Na+-Ca2+ Exchanger NCLX and the Sarcoplasmic Reticulum Ca2+ Pump SERCA in Cardiomyocytes by Takeuchi, Ayako, Matsuoka, Satoshi

“…The mitochondrial Na+-Ca2+ exchanger, NCLX, was reported to supply Ca2+ to sarcoplasmic reticulum (SR)/endoplasmic reticulum, thereby modulating various…”
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Minor contribution of NCX to Na+-Ca2+ exchange activity in brain mitochondria by Takeuchi, Ayako, Matsuoka, Satoshi

“…[Display omitted] •Both NCX and NCLX are expressed at mouse brain mitochondria.•Forward mode of mitochondrial Na+- or Li+-Ca2+ exchange is inhibited by a NCLX…”
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Temperature-modulated antibody drug separation using thermoresponsive mixed polymer brush-modified stationary phase by Nagase, Kenichi, Ishii, Saki, Takeuchi, Ayako, Kanazawa, Hideko

“…[Display omitted] •Mixed polymer brush composed thermoresponsive and affinity polymers was developed.•Exposing affinity polymer was controlled by changing…”
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Physiological and Pathophysiological Roles of Mitochondrial Na+-Ca2+ Exchanger, NCLX, in Hearts by Takeuchi, Ayako, Matsuoka, Satoshi

“…It has been over 10 years since SLC24A6/SLC8B1, coding the Na+/Ca2+/Li+ exchanger (NCLX), was identified as the gene responsible for mitochondrial Na+-Ca2+…”
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Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression by Uosaki, Hideki, Fukushima, Hiroyuki, Takeuchi, Ayako, Matsuoka, Satoshi, Nakatsuji, Norio, Yamanaka, Shinya, Yamashita, Jun K

“…Human embryonic and induced pluripotent stem cells (hESCs/hiPSCs) are promising cell sources for cardiac regenerative medicine. To realize hESC/hiPSC-based…”
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Physiological functions of mitochondrial Na+-Ca2+ exchanger, NCLX, in lymphocytes by Takeuchi, Ayako, Kim, Bongju, Matsuoka, Satoshi

“…[Display omitted] •NCLX is involved in mitochondria-ER Ca2+ recycling in B lymphocytes.•NCLX is important for Ca2+ response to B cell receptor stimulation,…”
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The destiny of Ca2+ released by mitochondria by Takeuchi, Ayako, Kim, Bongju, Matsuoka, Satoshi

“…Mitochondrial Ca 2+ is known to regulate diverse cellular functions, for example energy production and cell death, by modulating mitochondrial dehydrogenases,…”
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Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4) by Kasahara, Yoichi, Narukawa, Masataka, Takeuchi, Ayako, Tominaga, Makoto, Abe, Keiko, Asakura, Tomiko

“…The taste is biologically of intrinsic importance. It almost momentarily perceives environmental stimuli for better survival. In the early 2000s, research into…”
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Membrane current evoked by mitochondrial Na+–Ca2+ exchange in mouse heart by Islam, Mohammed M, Takeuchi, Ayako, Matsuoka, Satoshi

“…Abstract The electrogenicity of mitochondrial Na + –Ca 2+ exchange (NCXm) had been controversial and no membrane current through it had been reported. We…”
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TMC4 is a novel chloride channel involved in high-concentration salt taste sensation by Kasahara, Yoichi, Narukawa, Masataka, Ishimaru, Yoshiro, Kanda, Shinji, Umatani, Chie, Takayama, Yasunori, Tominaga, Makoto, Oka, Yoshitaka, Kondo, Kaori, Kondo, Takashi, Takeuchi, Ayako, Misaka, Takumi, Abe, Keiko, Asakura, Tomiko

“…"Salty taste" sensation is evoked when sodium and chloride ions are present together in the oral cavity. The presence of an epithelial cation channel that…”
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The mitochondrial Na+-Ca2+ exchanger, NCLX, regulates automaticity of HL-1 cardiomyocytes by Takeuchi, Ayako, Kim, Bongju, Matsuoka, Satoshi

“…Mitochondrial Ca 2+ is known to change dynamically, regulating mitochondrial as well as cellular functions such as energy metabolism and apoptosis. The NCLX…”
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A simulation study on the constancy of cardiac energy metabolites during workload transition by Saito, Ryuta, Takeuchi, Ayako, Himeno, Yukiko, Inagaki, Nobuya, Matsuoka, Satoshi

“…Key points The cardiac energy metabolites such as ATP, phosphocreatine, ADP and NADH are kept relatively constant during physiological cardiac workload…”
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Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia by Sasaki, Kenichi, Makiyama, Takeru, Yoshida, Yoshinori, Wuriyanghai, Yimin, Kamakura, Tsukasa, Nishiuchi, Suguru, Hayano, Mamoru, Harita, Takeshi, Yamamoto, Yuta, Kohjitani, Hirohiko, Hirose, Sayako, Chen, Jiarong, Kawamura, Mihoko, Ohno, Seiko, Itoh, Hideki, Takeuchi, Ayako, Matsuoka, Satoshi, Miura, Masaru, Sumitomo, Naokata, Horie, Minoru, Yamanaka, Shinya, Kimura, Takeshi

“…Human induced pluripotent stem cells (hiPSCs) offer a unique opportunity for disease modeling. However, it is not invariably successful to recapitulate the…”
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Roles of the mitochondrial Na+-Ca2+ exchanger, NCLX, in B lymphocyte chemotaxis by Kim, Bongju, Takeuchi, Ayako, Hikida, Masaki, Matsuoka, Satoshi

“…Lymphocyte chemotaxis plays important roles in immunological reactions, although the mechanism of its regulation is still unclear. We found that the cytosolic…”
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Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches by Hu, Yaopeng, Duan, Yubin, Takeuchi, Ayako, Hai-Kurahara, Lin, Ichikawa, Jun, Hiraishi, Keizo, Numata, Tomohiro, Ohara, Hiroki, Iribe, Gentaro, Nakaya, Michio, Mori, Masayuki X, Matsuoka, Satoshi, Ma, Genshan, Inoue, Ryuji

“…Transient receptor potential cation channel subfamily melastatin member 4 (TRPM4), a Ca2+-activated nonselective cation channel abundantly expressed in the…”
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Bias Correction of Multi-sensor Total Column Ozone Satellite Data for 1978–2017 by NAOE, Hiroaki, MATSUMOTO, Takanori, UENO, Keisuke, MAKI, Takashi, DEUSHI, Makoto, TAKEUCHI, Ayako

“…This study constructs a merged total column ozone (TCO) dataset using 20 available satellite Level 2 TCO (L2SAT) datasets over 40 years from 1978 to 2017. The…”
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Peering into an ATPase ion pump with single-channel recordings by Gadsby, David C, Takeuchi, Ayako, Artigas, Pablo, Reyes, Nicolás

“…In principle, an ion channel needs no more than a single gate, but a pump requires at least two gates that open and close alternately to allow ion access from…”
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Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage by Sakamaki, Kazuhiro, Ishii, Takahiro M., Sakata, Toshiya, Takemoto, Kiwamu, Takagi, Chiyo, Takeuchi, Ayako, Morishita, Ryo, Takahashi, Hirotaka, Nozawa, Akira, Shinoda, Hajime, Chiba, Kumiko, Sugimoto, Haruyo, Saito, Akiko, Tamate, Shuhei, Satou, Yutaka, Jung, Sang-Kee, Matsuoka, Satoshi, Koyamada, Koji, Sawasaki, Tatsuya, Nagai, Takeharu, Ueno, Naoto

“…Activation of caspases is crucial for the execution of apoptosis. Although the caspase cascade associated with activation of the initiator caspase-8 (CASP8)…”
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Ionic mechanisms of cardiac cell swelling induced by blocking Na+/K+ pump as revealed by experiments and simulation by Takeuchi, Ayako, Tatsumi, Shuji, Sarai, Nobuaki, Terashima, Keisuke, Matsuoka, Satoshi, Noma, Akinori

“…Although the Na(+)/K(+) pump is one of the key mechanisms responsible for maintaining cell volume, we have observed experimentally that cell volume remained…”
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Impairment of Ubiquitin–Proteasome System by E334K cMyBPC Modifies Channel Proteins, Leading to Electrophysiological Dysfunction by Bahrudin, Udin, Morikawa, Kumi, Takeuchi, Ayako, Kurata, Yasutaka, Miake, Junichiro, Mizuta, Einosuke, Adachi, Kaori, Higaki, Katsumi, Yamamoto, Yasutaka, Shirayoshi, Yasuaki, Yoshida, Akio, Kato, Masahiko, Yamamoto, Kazuhiro, Nanba, Eiji, Morisaki, Hiroko, Morisaki, Takayuki, Matsuoka, Satoshi, Ninomiya, Haruaki, Hisatome, Ichiro

“…Cardiac arrhythmogenesis is regulated by channel proteins whose protein levels are in turn regulated by the ubiquitin–proteasome system (UPS). We have…”
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