Search Results - "TAKETANI, SHIGERU"

Mitochondrial function provides instructive signals for activation-induced B-cell fates by Jang, Kyoung-Jin, Mano, Hiroto, Aoki, Koji, Hayashi, Tatsunari, Muto, Akihiko, Nambu, Yukiko, Takahashi, Katsu, Itoh, Katsuhiko, Taketani, Shigeru, Nutt, Stephen L., Igarashi, Kazuhiko, Shimizu, Akira, Sugai, Manabu

“…During immune reactions, functionally distinct B-cell subsets are generated by stochastic processes, including class-switch recombination (CSR) and plasma cell…”
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Platelet-rich plasma enhances the proliferation of human adipose stem cells through multiple signaling pathways by Lai, Fangyuan, Kakudo, Natsuko, Morimoto, Naoki, Taketani, Shigeru, Hara, Tomoya, Ogawa, Takeshi, Kusumoto, Kenji

“…Platelet-rich plasma (PRP) is an autologous blood product that contains a high concentration of several growth factors. Platelet-derived growth factor…”
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Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes by Minegishi, Saika, Yumura, Aki, Miyoshi, Hirotsuna, Negi, Shigeru, Taketani, Shigeru, Motterlini, Roberto, Foresti, Roberta, Kano, Koji, Kitagishi, Hiroaki

“…Carbon monoxide (CO) is produced in mammalian cells during heme metabolism and serves as an important signaling messenger. Here we report the bioactive…”
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Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation by Ma, Yuanyuan, Kakudo, Natsuko, Morimoto, Naoki, Lai, Fangyuan, Taketani, Shigeru, Kusumoto, Kenji

“…Human adipose-derived stem cells (hASCs) are a subset of mesenchymal stem cells (MSCs); it has been regarded as one of the most promising stem cells. We…”
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Continuous de novo biosynthesis of haem and its rapid turnover to bilirubin are necessary for cytoprotection against cell damage by Takeda, Taka-aki, Mu, Anfeng, Tai, Tran Tien, Kitajima, Sakihito, Taketani, Shigeru

“…It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain and drug metabolism…”
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FGF-2 combined with bilayer artificial dermis composed of collagen matrix prompts generation of fat pad in subcutis of mice by Kakudo, Natsuko, Morimoto, Naoki, Ogawa, Takeshi, Taketani, Shigeru, Kusumoto, Kenji

“…Fibroblast growth factor (FGF)-2 induces mitogenesis, angiogenesis and adipogenesis. In this study, the adipogenesis-inducing effects of FGF-2 combined with…”
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Aquisition, Mobilization and Utilization of Cellular Iron and Heme: Endless Findings and Growing Evidence of Tight Regulation by Taketani, Shigeru

“…Iron is fastidiously utilized by living cells, since it is an essential element, but is toxic in excess. Cells take up iron via a transferrin-transferrin…”
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Neurotransmitter Transporter Family Including SLC6A6 and SLC6A13 Contributes to the 5-Aminolevulinic Acid (ALA)-Induced Accumulation of Protoporphyrin IX and Photodamage, through Uptake of ALA by Cancerous Cells by Tran, Tai Tien, Mu, Anfeng, Adachi, Yuka, Adachi, Yasushi, Taketani, Shigeru

“…δ‐Aminolevulinic acid (ALA)‐induced protoporphyrin accumulation is widely used in the treatment of cancer, as photodynamic therapy (PDT). To clarify the…”
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Ferrochelatase Catalyzes the Formation of Zn-protoporphyrin of Dry-Cured Ham via the Conversion Reaction from Heme in Meat by Chau, Tuan Thanh, Ishigaki, Mutsumi, Kataoka, Takao, Taketani, Shigeru

“…Ferrochelatase (FECH), the enzyme at the last step of the heme-biosynthetic pathway, is involved in the formation of Zn-protoporphyrin via an iron-removal…”
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p53 directly regulates the transcription of the human frataxin gene and its lack of regulation in tumor cells decreases the utilization of mitochondrial iron by Shimizu, Rina, Lan, Nguyen Ngoc, Tai, Tran Tien, Adachi, Yuka, Kawazoe, Asako, Mu, Anfeng, Taketani, Shigeru

“…Mitochondrial frataxin functions in iron homeostasis, biogenesis of iron–sulfur clusters, protection from oxidative stress and apoptosis, and as a tumor…”
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Activation of cell adhesion and migration is an early event of platelet-rich plasma (PRP)-dependent stimulation of human adipose-derived stem/stromal cells by Fukui, Michika, Lai, Fangyuan, Hihara, Masakatsu, Mitsui, Toshihito, Matsuoka, Yuki, Sun, Zhongxin, Kunieda, Sakurako, Taketani, Shigeru, Odaka, Tokifumi, Okuma, Kazu, Kakudo, Natsuko

“…Stem cell therapy is a promising treatment in regenerative medicine. Human adipose-derived stem/stromal cells (hASCs), a type of mesenchymal stem cell, are…”
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Hypoxia Enhances Proliferation of Human Adipose-Derived Stem Cells via HIF-1ɑ Activation by Kakudo, Natsuko, Morimoto, Naoki, Ogawa, Takeshi, Taketani, Shigeru, Kusumoto, Kenji

“…Adipose tissue-derived stem cells (ASCs) have been recently isolated from human subcutaneous adipose tissue. ASCs may be useful in regenerative medicine as an…”
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Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate by Kelter, Gerhard, Steinbach, Daniel, Konkimalla, Venkata Badireenath, Tahara, Tsuyoshi, Taketani, Shigeru, Fiebig, Heinz-Herbert, Efferth, Thomas

“…The anti-malarial artesunate also exerts profound anti-cancer activity. The susceptibility of tumor cells to artesunate can be enhanced by ferrous iron. The…”
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Stem Cell Replacement Improves Expression of SMP30 in db/db Mice by Li, Ming, Guo, Kequan, Taketani, Shigeru, Adachi, Yasushi, Ikehara, Susumu

“…We have previously reported that replacing bone marrow stem cells may improve hyperglycemia and oxidative stress in db/db mice, a type 2 diabetic mouse model…”
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The p53-Dependent Expression of Frataxin Controls 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX and Photo-Damage in Cancerous Cells by Sawamoto, Mari, Imai, Takafumi, Umeda, Mana, Fukuda, Koji, Kataoka, Takao, Taketani, Shigeru

“…Mitochondrial frataxin is involved in various functions such as iron homeostasis, iron–sulfur cluster biogenesis, the protection from oxidative stress and…”
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Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene by Mori, Masayuki, Gotoh, Saki, Taketani, Shigeru, Hiai, Hiroshi, Higuchi, Keiichi

“…The Nakano cataract (NCT) is a recessive disorder in the mouse linked to the nct locus on chromosome 16. In this study, we positionally cloned the critical…”
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Mitochondrial localization of ferrochelatase in a red alga Cyanidioschyzon merolae by Watanabe, Satoru, Hanaoka, Mitsumasa, Ohba, Yusaku, Ono, Tomohiro, Ohnuma, Mio, Yoshikawa, Hirofumi, Taketani, Shigeru, Tanaka, Kan

“…Ferrochelatase (FECH) is an essential enzyme for the final step of heme biosynthesis. In green plants, its activity has been reported in both plastids and…”
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Porcine Ferrochelatase: The Relationship between Iron-Removal Reaction and the Conversion of Heme to Zn-Protoporphyrin by CHAU, Tuan Thanh, ISHIGAKI, Mutsumi, KATAOKA, Takao, TAKETANI, Shigeru

“…At the terminal step of heme biosynthesis, ferrochelatase (FECH) catalyzes the insertion of Fe 2+ into protoporphyrin to form heme. It is located on the inner…”
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Late-onset Erythropoietic Protoporphyria Associated with Myelodysplastic Syndrome Treated with Azacitidine by Yoshioka, Ai, Fujiwara, Susumu, Kawano, Hiroki, Nakano, Hajime, Taketani, Shigeru, Matsui, Toshimitsu, Katayama, Yoshio, Nishigori, Chikako

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Change in the developmental fate of the chick optic vesicle from the neural retina to the telencephalon by Shirahama, Misaki, Steinfeld, Ichie, Karaiwa, Akari, Taketani, Shigeru, Vogel‐Höpker, Astrid, Layer, Paul G., Araki, Masasuke

“…The forebrain develops into the telencephalon, diencephalon, and optic vesicle (OV). The OV further develops into the optic cup, the inner and outer layers of…”
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