Search Results - "TAKESHI USUI"

Pharmaceutical Prospects of Phytoestrogens by USUI, Takeshi

“…Interest in the physiologic and pharmacologic role of bioactive compounds present in plants has increased dramatically over the last decade. Of particular…”
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A case of retinitis pigmentosa homozygous for a rare CNGA1 causal variant by Saito, Kohei, Gotoh, Norimoto, Kang, Inyeop, Shimada, Toshio, Usui, Takeshi, Terao, Chikashi

“…Retinitis pigmentosa (RP) is a heterogenous hereditary disorder leading to blindness. Despite using next-generation sequencing technologies, causal variants in…”
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Pancreatic cancer risk in diabetic patients using the Japanese Regional Insurance Claims by Satoh, Tatsunori, Nakatani, Eiji, Ariyasu, Hiroyuki, Kawaguchi, Shinya, Ohno, Kazuya, Itoh, Hiroshi, Hayashi, Kaori, Usui, Takeshi

“…Pancreatic cancer presents a critical health issue characterized by low survival rates. Identifying risk factors in specific populations, such as those with…”
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Histopathological Diagnosis of Primary Aldosteronism Using CYP11B2 Immunohistochemistry by Nanba, Kazutaka, Tsuiki, Mika, Sawai, Kuniko, Mukai, Kuniaki, Nishimoto, Koshiro, Usui, Takeshi, Tagami, Tetsuya, Okuno, Hiroshi, Yamamoto, Tetsuro, Shimatsu, Akira, Katabami, Takuyuki, Okumura, Ataru, Kawa, Gen, Tanabe, Akiyo, Naruse, Mitsuhide

“…Context: Although primary aldosteronism (PA) is the most common cause of endocrine hypertension, histopathological methods to reveal the presence and sites of…”
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Identification of a homozygous c.1039C>T (p.R347C) variant in CYP17A1 in a 67-year-old female patient with partial 17α-hydroxylase/17,20-lyase deficiency by Yamagata, Satoshi, Kageyama, Kazunori, Usui, Takeshi, Saito, Kohei, Takayasu, Shinobu, Usutani, Mari, Terui, Ken, Daimon, Makoto

“…17α-Hydroxylase/17,20-lyase deficiency (17OHD) is caused by pathogenic mutations in CYP17A1. Impaired 17α-hydroxylase and 17,20-lyase activities typically…”
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Familial congenital choanal atresia with GATA3 associated hypoparathyroidism-deafness-renal dysplasia syndrome unidentified on auditory brainstem response by Kita, Makoto, Kuwata, Yasuhiro, Usui, Takeshi

“…Hypoparathyroidism-deafness-renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder primarily caused by GATA3 haploinsufficiency and is…”
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Retroperitoneal paraganglioma with loss of heterozygosity of the von Hippel–Lindau gene: a case report and review of the literature by Anno, Mari, Izawa, Shoichiro, Fujioka, Yohei, Matsuzawa, Kazuhiko, Saito, Kohei, Hikita, Katsuya, Makishima, Karen, Nosaka, Kanae, Takenaka, Atsushi, Usui, Takeshi, Yamamoto, Kazuhiro

“…Von Hippel–Lindau (VHL) disease is an autosomal dominant disease related to germline mutations in VHL. In VHL disease, pheochromocytoma develops in 10%–20% of…”
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Comparisons of plasma aldosterone and renin data between an automated chemiluminescent immunoanalyzer and conventional radioimmunoassays in the screening and diagnosis of primary aldosteronism by Tamura, Naohisa, Watanabe, Erika, Shirakawa, Rumi, Nakatani, Eiji, Yamada, Kanako, Hatakeyama, Hiroshi, Torii-Hanakita, Mizuki, Kyo, Chika, Kosugi, Rieko, Ogawa, Tatsuo, Kotani, Masato, Usui, Takeshi, Inoue, Tatsuhide

“…Determining values of plasma renin activity (PRA) or plasma active renin concentration (ARC), plasma aldosterone concentration (PAC), and aldosterone-to-renin…”
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Prions disturb post-Golgi trafficking of membrane proteins by Uchiyama, Keiji, Muramatsu, Naomi, Yano, Masashi, Usui, Takeshi, Miyata, Hironori, Sakaguchi, Suehiro

“…Conformational conversion of normal cellular prion protein PrP C into pathogenic PrP Sc is central to the pathogenesis of prion diseases. However, the…”
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Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist by Moriyama, Kenji, Tagami, Tetsuya, Akamizu, Takashi, Usui, Takeshi, Saijo, Misa, Kanamoto, Naotetsu, Hataya, Yuji, Shimatsu, Akira, Kuzuya, Hideshi, Nakao, Kazuwa

“…Bisphenol A (BPA), a monomer of polycarbonate plastics, has been shown to possess estrogenic properties and act as an agonist for the estrogen receptors…”
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Parameters of captopril challenge test can predict results of other confirmatory tests for primary aldosteronism and propose the next test to be done by Tamura, Naohisa, Yamada, Kanako, Hatakeyama, Hiroshi, Torii-Hanakita, Mizuki, Kyo, Chika, Kosugi, Rieko, Yonemoto, Takako, Ogawa, Tatsuo, Kotani, Masato, Usui, Takeshi, Inoue, Tatsuhide

“…In Japan, primary aldosteronism (PA) is diagnosed if any one of the captopril challenge test (CCT), saline infusion test (SIT), furosemide-upright test (FUP),…”
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Prevention of type 2 diabetes in a primary healthcare setting: three-year results of lifestyle intervention in Japanese subjects with impaired glucose tolerance by Sakane, Naoki, Sato, Juichi, Tsushita, Kazuyo, Tsujii, Satoru, Kotani, Kazuhiko, Tsuzaki, Kokoro, Tominaga, Makoto, Kawazu, Shoji, Sato, Yuzo, Usui, Takeshi, Kamae, Isao, Yoshida, Toshihide, Kiyohara, Yutaka, Sato, Shigeaki, Kuzuya, Hideshi

“…A randomized control trial was performed to test whether a lifestyle intervention program, carried out in a primary healthcare setting using existing…”
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What Equol Can Do for Human Health? by Takeshi Usui

“…Although soy is considered to be beneficial for various health problems, including postmenopausal symptoms, osteoporosis,lipid metabolism, and obesity based on…”
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Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans by Ariyasu, Hiroyuki, Takaya, Kazuhiko, Tagami, Tetsuya, Ogawa, Yoshihiro, Hosoda, Kiminori, Akamizu, Takashi, Suda, Michio, Koh, Toshikiyo, Natsui, Koshi, Toyooka, Shigetake, Shirakami, Gotaro, Usui, Takeshi, Shimatsu, Akira, Doi, Kentaro, Hosoda, Hiroshi, Kojima, Masayasu, Kangawa, Kenji, Nakao, Kazuwa

“…Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat stomach and is involved in a novel system for regulating GH release…”
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Confirmatory Testing in Primary Aldosteronism by Nanba, Kazutaka, Tamanaha, Tamiko, Nakao, Kanako, Kawashima, Sachiko-Tsukamoto, Usui, Takeshi, Tagami, Tetsuya, Okuno, Hiroshi, Shimatsu, Akira, Suzuki, Tomoko, Naruse, Mitsuhide

“…Context: Although confirmatory testing to verify aldosterone excess is a key step in the diagnosis of primary aldosteronism (PA), there is no consensus as to…”
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High-dose fludrocortisone therapy was transiently required in a female neonate with 21-hydroxylase deficiency by Kawasaki, Yusuke, Sato, Takeshi, Nakano, Satsuki, Usui, Takeshi, Narumi, Satoshi, Ishii, Tomohiro, Hasegawa, Tomonobu

“…For salt-wasting 21-hydroxylase deficiency (21OHD), fludrocortisone (FC) is usually supplemented at 0.05–0.2 mg/d dose. To date, no report has described 21OHD…”
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Ghrelin Strongly Stimulates Growth Hormone Release in Humans by Takaya, Kazuhiko, Ariyasu, Hiroyuki, Kanamoto, Naotetsu, Iwakura, Hiroshi, Yoshimoto, Akihiro, Harada, Masaki, Mori, Kiyoshi, Komatsu, Yasato, Usui, Takeshi, Shimatsu, Akira, Ogawa, Yoshihiro, Hosoda, Kiminori, Akamizu, Takashi, Kojima, Masayasu, Kangawa, Kenji, Nakao, Kazuwa

“…Ghrelin is a recently identified endogenous ligand for the GH secretagogue receptor and is involved in a novel system for regulating GH release. However,…”
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Endometrial Cancer Diagnosed at an Early Stage during Lynch Syndrome Surveillance: A Case Report by Umemiya, Maki, Horikawa, Naoki, Kanai, Ami, Saeki, Ayaka, Ida, Kohei, Makio, Satoru, Yoshida, Teruki, Tsuji, Mitsuru, Gou, Rei, Tani, Hirohiko, Usui, Takeshi, Kosaka, Kenzo

“…Abstract Lynch syndrome is an autosomal dominant inherited disorder caused by a germline pathogenic variant in DNA mismatch repair genes, resulting in…”
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Importance of the Average Glucose Level and Estimated Glycated Hemoglobin in a Diabetic Patient with Hereditary Hemolytic Anemia and Liver Cirrhosis by Nakatani, Rieko, Murata, Takashi, Usui, Takeshi, Moriyoshi, Koki, Komeda, Toshiki, Masuda, Yuichi, Kakita-Kobayashi, Maiko, Tagami, Tetsuya, Imashuku, Shinsaku, Kono, Shigeo, Yamada, Kazunori, Shimatsu, Akira

“…Glycated hemoglobin (HbA1c) is a widely used marker of glycemic control but can be affected by hemolytic anemia. Glycated albumin (GA) is also affected in…”
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Unusual Proliferative Glomerulonephritis in a Patient Diagnosed to Have Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome with a Novel Mutation in the GATA3 Gene by Kamezaki, Michitsugu, Kusaba, Tetsuro, Adachi, Takaomi, Yamashita, Noriyuki, Nakata, Mayumi, Ota, Noriyoshi, Shiotsu, Yayoi, Ishida, Mami, Usui, Takeshi, Tamagaki, Keiichi

“…Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disease caused by GATA3 mutations. Although several…”
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