Search Results - "TAKEICHI, Yoh'ichiro"
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Improvement of solubility and oral bioavailability of a poorly water-soluble drug, TAS-301, by its melt-adsorption on a porous calcium silicate
Published in Journal of pharmaceutical sciences (01-02-2002)“…The aim of the present study was to improve the solubility and oral bioavailability of a poorly water-soluble drug, 3-bis(4-methoxyphenyl)…”
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Improvement of Aqueous Solubility and Rectal Absorption of 6-Mercaptopurine by Addition of Sodium Benzoate
Published in Biological & pharmaceutical bulletin (1994)“…The solubility of 6-mercaptopurine (6-MP) in water increased as the concentration of sodium benzoate or sodium hippurate in the solution increased. The…”
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Molecular Behavior and Dissolution Characteristics of Uracil in Ground Mixtures
Published in Chemical & pharmaceutical bulletin (1990)“…Ground mixtures containing uracill were prepared using various additives such as celluloses, proteins, cyclodextrins, enteric coating agents and inorganic…”
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Combinative Improving Effect of Increased Solubility and the Use of Absorption Enhancers on the Rectal Absorption of Uracil in Beagle Dogs
Published in Chemical & pharmaceutical bulletin (1990)“…An improvement of the rectal absorption of uracil was examined by the application of absorption enhancers in addition to the increased solubility of…”
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A Novel Method for the Preclinical Assessment of Rectal Irritation
Published in Journal of pharmacy and pharmacology (01-03-1996)“…The purpose of this study concerns a novel method for preclinical assessment of rectal irritation caused by suppositories introduced into the rectum. Rectal…”
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Effects of Fluidity and Vesicle Size on Antitumor Activity and Myelosuppressive Activity of Liposomes Loaded with Daunorubicin
Published in Biological & pharmaceutical bulletin (01-07-1994)“…The effects of fluidity and vesicle size on the antitumor activity and myelosuppressive activity of liposomes loaded with daunorubicin, an anthracycline…”
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Simultaneous determination of a new dihydropyridine calcium antagonist (MPC-1304) and its metabolite in dog plasma by high-performance liquid chromatography with electrochemical detection
Published in Journal of chromatography (15-11-1991)“…A rapid and sensitive high-performance liquid chromatographic analysis, with electrochemical detection, has been developed for the simultaneous determination…”
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