Search Results - "TAKEDA, Yoshiyu"

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    Epigenetic Regulation of the Renin-Angiotensin-Aldosterone System in Hypertension by Takeda, Yoshimichi, Demura, Masashi, Yoneda, Takashi, Takeda, Yoshiyu

    “…Activation of the renin-angiotensin-aldosterone system (RAAS) plays an important pathophysiological role in hypertension. Increased mRNA levels of the ,…”
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    Journal Article
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    DNA Methylation of the Angiotensinogen Gene, AGT , and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases by Takeda, Yoshimichi, Demura, Masashi, Yoneda, Takashi, Takeda, Yoshiyu

    “…Angiotensinogen (AGT) and aldosterone play key roles in the regulation of blood pressure and are implicated in the pathogenesis of cardiovascular diseases. DNA…”
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    Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1 by Takeda, Yoshimichi, Demura, Masashi, Kometani, Mitsuhiro, Karashima, Shigehiro, Yoneda, Takashi, Takeda, Yoshiyu

    “…Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular diseases and metabolic disorders. Epigenetics is a mechanism to control…”
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    Primary aldosteronism subtype discordance between computed tomography and adrenal venous sampling by Aono, Daisuke, Kometani, Mitsuhiro, Karashima, Shigehiro, Usukura, Mikiya, Gondo, Yuko, Hashimoto, Atsushi, Demura, Masashi, Furukawa, Kenji, Takeda, Yoshiyu, Kawashiri, Masaaki, Yoneda, Takashi

    Published in Hypertension research (01-12-2019)
    “…The primary aldosteronism (PA) subtype is usually confirmed by CT and adrenal venous sampling (AVS). However, the subtype diagnosis by AVS is not necessarily…”
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    Comparison of eplerenone and spironolactone for the treatment of primary aldosteronism by Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Ohe, Masashi, Mori, Shunsuke, Sawamura, Toshitaka, Furukawa, Kenji, Seta, Takashi, Yamagishi, Masakazu, Takeda, Yoshiyu

    Published in Hypertension research (01-03-2016)
    “…The mineralocorticoid receptor (MR) is expressed in the kidneys and in adipose tissue, and primary aldosteronism (PA) is associated with metabolic syndrome…”
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    Adrenal Hemorrhaging in a Patient with Severe Obstructive Sleep Apnea Syndrome with Elevated Plasma ACTH Levels by Sawamura, Toshitaka, Karashima, Shigehiro, Aono, Daisuke, Ohmori, Ai, Kometani, Mitsuhiro, Takeda, Yoshiyu, Yoneda, Takashi

    Published in Internal Medicine (01-08-2023)
    “…Adrenal hemorrhaging (AH) is a rare condition characterized by bleeding into the suprarenal glands. A 62-year-old man with untreated obstructive sleep apnea…”
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    Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism by Takeda, Yoshimichi, Demura, Masashi, Kometani, Mitsuhiro, Karashima, Shigehiro, Aono, Daisuke, Konishi, Seigo, Horike, Shin-ichi, Meguro-Horike, Makiko, Yoneda, Takashi, Takeda, Yoshiyu

    Published in Endocrine Journal (01-01-2024)
    “…11Beta-hydroxysteroid dehydrogenase 1 (11β-HSD1) is a key enzyme involved in metabolic syndrome. Transcript-specific epigenetic regulation of the gene encoding…”
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    Journal Article
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    Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice by Hashimoto, Atsushi, Takeda, Yoshimichi, Karashima, Shigehiro, Kometani, Mitsuhiro, Aono, Daisuke, Demura, Masashi, Higashitani, Takuya, Konishi, Seigo, Yoneda, Takashi, Takeda, Yoshiyu

    Published in Hypertension research (01-10-2020)
    “…It has been suggested that aldosterone breakthrough during treatment with a type 1 angiotensin II receptor (AT1R) blocker (ARB) may be an important risk factor…”
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    Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension by Takeda, Yoshiyu

    Published in Hypertension research (01-05-2009)
    “…Mineralocorticoid receptors (MRs) are expressed in non-epithelial tissues, such as blood vessels, the heart and adipose tissue. The combined effects of…”
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    Effect of sodium glucose cotransporter 2 inhibitors on obstructive sleep apnea in patients with type 2 diabetes by Sawada, Kei, Karashima, Shigehiro, Kometani, Mitsuhiro, Oka, Rie, Takeda, Yoshimichi, Sawamura, Toshitaka, Fujimoto, Aya, Demura, Masashi, Wakayama, Ayako, Usukura, Mikiya, Yagi, Kunimasa, Takeda, Yoshiyu, Yoneda, Takashi

    Published in Endocrine Journal (01-01-2018)
    “…Obstructive sleep apnea syndrome (OSAS) is often associated with metabolic disorders such as obesity and type 2 diabetes and may contribute to cardiovascular…”
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    Prevalence of primary aldosteronism among prehypertensive and stage 1 hypertensive subjects by Ito, Yuji, Takeda, Ryoyu, Karashima, Shigehiro, Yamamoto, Yasuhiro, Yoneda, Takashi, Takeda, Yoshiyu

    Published in Hypertension research (01-01-2011)
    “…Recent studies have reported a high prevalence of primary aldosteronism among patients with severe hypertension. However, the prevalence of this disease among…”
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    Predictor of Steroid Replacement Duration after Removal of Cortisol-producing Adenoma by Kubo, Yui, Sone, Masakatsu, Katabami, Takuyuki, Izawa, Shoichiro, Ichijo, Takamasa, Tsuiki, Mika, Okamura, Shintaro, Yoshimoto, Takanobu, Otsuki, Michio, Takeda, Yoshiyu, Suzuki, Tomoko, Naruse, Mitsuhide, Tanabe, Akiyo, Group, ACPA-J Study

    Published in Internal Medicine (18-10-2024)
    “…Objective Cortisol-producing adenoma (CPA) is a major subtype of functional adrenal tumors. CPAs are generally treated with adrenalectomy; however, it is…”
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    Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study by Kometani, Mitsuhiro, Yoneda, Takashi, Aono, Daisuke, Gondoh-Noda, Yuko, Matsuoka, Takahiro, Higashitani, Takuya, Yoshikura, Shohei, Sawada, Kei, Takeda, Yoshimichi, Fujimoto, Aya, Karashima, Shigehiro, Usukura, Mikiya, Takeda, Yoshiyu

    Published in Internal Medicine (01-04-2021)
    “…Objective Primary aldosteronism (PA) is a major cause of secondary hypertension. The association between PA and other hormone disorders is unclear. The present…”
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