Search Results - "TAKEDA, SHIGEFUMI"
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Cognitive Improving and Cerebral Protective Effects of Acylated Oligosaccharides in Polygala tenuifolia
Published in Biological & Pharmaceutical Bulletin (01-07-2004)“…We studied the cognitive improving and cerebral protective constituents in the roots of Polygala tenuifolia WILLDENOW, a well-known Chinese traditional…”
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Effect of Gomisin A (TJN-101) on liver regeneration
Published in Planta medica (01-12-1992)“…We studied the effect of TJN-101, a lignan component of Schisandra fruits (Schisandrae fructus), on liver regeneration after partial hepatectomy. TJN-101 was…”
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VOMITING INDUCTION BY IPECAC SYRUP IN DOGS AND FERRETS
Published in Journal of toxicological sciences (1997)“…The dog has been used as an experimental animal in emesis research. In this study, we analyzed the emetic effects of ipecac syrup using a smaller animal, the…”
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Evaluation of gastric adaptive relaxation in isolated stomach from the guinea-pig
Published in Nippon Shōkakibyō Gakkai zasshi (1995)“…To evaluate the mechanism of gastric adaptive relaxation (GAR), we designed and established the experimental system for the measurement of GAR in isolated…”
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Effect of gomisin A (TJN-101), a lignan compound isolated from Schisandra fruits, on liver function in rats
Published in Nihon yakurigaku zasshi (1988)“…TJN-101 [+)-(6S, 7S, R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy- 6,7-dimethyl-10,11-methylenedioxy-6-dibenzo [a, c] cyclooctenol) is one of the lignan…”
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Effects of Gomisin A (TJN-101), a lignan compound from Schisandra fruits, on liver metabolism in rats
Published in Japanese Journal of Pharmacology (1990)“…We previously reported that TJN-101 (T), a lignan compound isolated from Schisandra fruits, enhances liver functions, including induction of drug-metabolizing…”
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The choleretic mechanism of coumarin compounds and phenolic compounds
Published in Journal of pharmacobio-dynamics (01-01-1981)“…In this work, the choleretic properties and mechanism of coumarin compounds and phenolic compounds were studied by examining their effects on parameters such…”
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Effects of gomisin A, a lignan component of Schizandra fruits, on experimental liver injuries and liver microsomal drug-metabolizing enzymes
Published in Nihon yakurigaku zasshi (01-02-1986)“…Effects of oral administration of gomisin A, one of the components isolated from Schizandra fruits, on liver injuries induced by CCl4, d-galactosamine and…”
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Effects of Gomisin A on Hepatocarcinogenesis by 3’-Methyl-4-dimethylaminoazobenzene in Rats
Published in Japanese Journal of Pharmacology (1991)“…We examined the effects of gomisin A on tumor promotion in the liver after a short-term feeding of 3’-methyl-4-dimethylaminoazobenzene (3’-MeDAB) to rats,…”
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Pharmacological studies on iridoid compounds. III. The choleretic mechanism of iridoid compounds
Published in Journal of pharmacobio-dynamics (1981)“…We made a study on choleretic property and mechanism of action of iridoid compounds as well as dehydrocholate (DHC), cholate (CA), and salicylate (SA),…”
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Effects of Gomisin A on Liver Functions in Hepatotoxic Chemicals-Treated Rats
Published in Japanese journal of pharmacology (01-01-1985)“…The effects of gomisin A, which is a lignan component of schizandra fruits, on liver functions in various experimental liver injuries and on bile secretion in…”
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Effects of TJN-101, a lignan compound isolated from Schisandra fruits, on liver fibrosis and on liver regeneration after partial hepatectomy in rats with chronic liver injury induced by CCl4
Published in Nihon yakurigaku zasshi (1987)“…TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy -6,7-dimethyl-10,11-methylenedioxy-6-dibenzo[a,c]cyclooctenol) is one of the lignan…”
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Pharmacological studies of gardenia fruit. V. Mechanisms of inhibitory effect of genipin on gastric acid secretion and its facilitatory effect on bile secretion in rats
Published in Journal of pharmacobio-dynamics (1980)“…In the experiment on continuous perfusion of rat stomach in vivo, genipin inhibited only the gastric acid secretion induced by carbachol, but not by…”
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Effects of iridoid compounds on bile flow
Published in Nippon Shōkakibyō Gakkai zasshi (01-12-1985)Get more information
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Protective effects of juzentaihoto, dried decoctum of 10 Chinese herbs mixture, upon the adverse effects of mitomycin C in mice
Published in Journal of pharmacobio-dynamics (01-01-1983)“…In view of the reduction of side effects as well as the enhancement of anti-tumor activities of anticancer drugs, we have been interested in the combined use…”
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Inhibitory Effect of TJN-101 ((+)-(6S,7S,R-Biar)-5,6,7,8-Tetrahydro-1,2,3,12-Tetramethoxy-6,7-Dimethyl-10,11-Methylenedioxy-6-Dibenzo[a,c]cyclooctenol) on Immunologically Induced Liver Injuries
Published in Japanese journal of pharmacology (1987)“…TJN-101, which is a lignan component isolated from schisandra fruits, inhibits hepatotoxic chemicals-induced liver injuries. In this study, effects of TJN-101…”
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Gomisin A(TJN-101)の体内動態に関する研究(第2報)四塩化炭素肝障害ラットにおける吸収及び排泄
Published in YAKUGAKU ZASSHI (1991)Get full text
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Studies on the Metabolic Fate of Gomisin A (TJN-101). II. Absorption and Excretion in CCl4 Treated Rats
Published in YAKUGAKU ZASSHI (01-09-1991)“…The absorption and excretion of gomisin A (TJN-101) in rats whose livers were injured by carbon tetrachloride (CCl4) were investigated. After intravenous…”
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