Search Results - "TAKASHI SAITO"

A lithium superionic conductor for millimeter-thick battery electrode by Li, Yuxiang, Song, Subin, Kim, Hanseul, Nomoto, Kuniharu, Kim, Hanvin, Sun, Xueying, Hori, Satoshi, Suzuki, Kota, Matsui, Naoki, Hirayama, Masaaki, Mizoguchi, Teruyasu, Saito, Takashi, Kamiyama, Takashi, Kanno, Ryoji

“…No design rules have yet been established for producing solid electrolytes with a lithium-ion conductivity high enough to replace liquid electrolytes and…”
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Novel Bioactive Adhesive Monomer CMET Promotes Odontogenic Differentiation and Dentin Regeneration by Qiu, Youjing, Saito, Takashi

“…This study aimed to evaluate the in vitro effect of the novel bioactive adhesive monomer CMET, a calcium salt of 4-methacryloxyethyl trimellitate acid (4-MET),…”
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High Oxide‐Ion Conductivity through the Interstitial Oxygen Site in Sillén Oxychlorides by Yaguchi, Hiroshi, Morikawa, Daisuke, Saito, Takashi, Tsuda, Kenji, Yashima, Masatomo

“…Oxide‐ion conductors are gaining attention as future materials in energy applications, such as solid oxide fuel cells. Many Bi‐containing compounds exhibit…”
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Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease by Zhang, Hua, Wu, Lili, Pchitskaya, Ekaterina, Zakharova, Olga, Saito, Takashi, Saido, Takaomi, Bezprozvanny, Ilya

“…Alzheimer's disease (AD) is the most common reason for elderly dementia in the world. We proposed that memory loss in AD is related to destabilization of…”
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Barriers to the Utilization of Low-Vision Rehabilitation Services among Over-50-Year-Old People in East and Southeast Asian Regions: A Scoping Review by Takashi, Saito, Kumiko, Imahashi

“…East and Southeast Asia (ESEA) are facing age-related eye health issues. Low-vision rehabilitation (LVR), which is a special rehabilitation service for…”
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ScaleS: an optical clearing palette for biological imaging by Hama, Hiroshi, Hioki, Hiroyuki, Namiki, Kana, Hoshida, Tetsushi, Kurokawa, Hiroshi, Ishidate, Fumiyoshi, Kaneko, Takeshi, Akagi, Takumi, Saito, Takashi, Saido, Takaomi, Miyawaki, Atsushi

“…Sca l eS is a tissue clearing method for light and electron microscopy featuring stable tissue preservation for immunochemical and genetic labeling of tissue…”
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Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease by Jun, Heechul, Bramian, Allen, Soma, Shogo, Saito, Takashi, Saido, Takaomi C., Igarashi, Kei M.

“…Patients with Alzheimer's disease (AD) suffer from spatial memory impairment and wandering behavior, but the brain circuit mechanisms causing such symptoms…”
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Neuroinflammation in mouse models of Alzheimer's disease by Saito, Takashi, Saido, Takaomi C.

“…Alzheimer's disease (AD) is the most common type of neurocognitive disorder. Although both amyloid β peptide deposition and neurofibrillary tangle formation in…”
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Ultra-large single crystals by abnormal grain growth by Kusama, Tomoe, Omori, Toshihiro, Saito, Takashi, Kise, Sumio, Tanaka, Toyonobu, Araki, Yoshikazu, Kainuma, Ryosuke

“…Producing a single crystal is expensive because of low mass productivity. Therefore, many metallic materials are being used in polycrystalline form, even…”
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Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression by Saito, Takashi, Matsuba, Yukio, Yamazaki, Naomi, Hashimoto, Shoko, Saido, Takaomi C

“…Intraneuronal calcium stimulates the calpain-dependent conversion of p35 to p25, a CDK5 activator. It is widely believed that amyloid β peptide (Aβ) induces…”
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Biocompatibility of Novel Type I Collagen Purified from Tilapia Fish Scale: An In Vitro Comparative Study by Tang, Jia, Saito, Takashi

“…Type I collagen (COL-1) is the prevailing component of the extracellular matrix in a number of tissues including skin, ligament, cartilage, bone, and dentin…”
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Oxygen Reduction Reaction Catalytic Activities of Pure Ni-Based Perovskite-Related Structure Oxides by Abe, Yoshiyuki, Satoh, Iwao, Saito, Takashi, Kan, Daisuke, Shimakawa, Yuichi

“…Complex transition-metal oxides offer an interesting class of materials for use as oxygen reduction reaction (ORR) catalysts. A recent study proposed a…”
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Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation by Saito, Takashi, Mihira, Naomi, Matsuba, Yukio, Sasaguri, Hiroki, Hashimoto, Shoko, Narasimhan, Sneha, Zhang, Bin, Murayama, Shigeo, Higuchi, Makoto, Lee, Virginia M.Y., Trojanowski, John Q., Saido, Takaomi C.

“…In cortical regions of brains from individuals with preclinical or clinical Alzheimer's disease (AD), extracellular β-amyloid (Aβ) deposition precedes the…”
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Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model by Clayton, Kevin, Delpech, Jean Christophe, Herron, Shawn, Iwahara, Naotoshi, Ericsson, Maria, Saito, Takashi, Saido, Takaomi C, Ikezu, Seiko, Ikezu, Tsuneya

“…Recent studies suggest that microglia contribute to tau pathology progression in Alzheimer's disease. Amyloid plaque accumulation transforms microglia, the…”
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Antifibrotic therapy by sustained release of low molecular weight heparin from poly(lactic-co-glycolic acid) microparticles on bleomycin-induced pulmonary fibrosis in mice by Saito, Takashi, Kotani, Takuya, Suzuki, Koichi

“…Heparin and low molecular weight heparin (LMWH) have recently been considered useful treatment tools for inflammation. Heparin has antifibrotic activity,…”
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Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice by Park, Hanseul, Cho, Byounggook, Kim, Hongwon, Saito, Takashi, Saido, Takaomi C., Won, Kyoung-Jae, Kim, Jongpil

“…Alzheimer’s disease (AD) is associated with progressive neuronal degeneration as amyloid-beta (Aβ) and tau proteins accumulate in the brain. Glial cells were…”
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Aberrant Excitatory-Inhibitory Synaptic Mechanisms in Entorhinal Cortex Microcircuits During the Pathogenesis of Alzheimer's Disease by Petrache, Alexandra L, Rajulawalla, Aarib, Shi, Anqi, Wetzel, Andrea, Saito, Takashi, Saido, Takaomi C, Harvey, Kirsten, Ali, Afia B

“…Abstract Synaptic dysfunction is widely proposed as an initial insult leading to the neurodegeneration observed in Alzheimer's disease (AD). We hypothesize…”
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Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease by Sobue, Akira, Komine, Okiru, Hara, Yuichiro, Endo, Fumito, Mizoguchi, Hiroyuki, Watanabe, Seiji, Murayama, Shigeo, Saito, Takashi, Saido, Takaomi C, Sahara, Naruhiko, Higuchi, Makoto, Ogi, Tomoo, Yamanaka, Koji

“…Microglia-mediated neuroinflammation has been implicated in the pathogenesis of Alzheimer's disease (AD). Although microglia in aging and neurodegenerative…”
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SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice by Liu, Yong, Cheng, Aiwu, Li, Yu-Jiao, Yang, Ying, Kishimoto, Yuki, Zhang, Shi, Wang, Yue, Wan, Ruiqian, Raefsky, Sophia M., Lu, Daoyuan, Saito, Takashi, Saido, Takaomi, Zhu, Jian, Wu, Long-Jun, Mattson, Mark P.

“…Intermittent food deprivation (fasting, IF) improves mood and cognition and protects neurons against excitotoxic degeneration in animal models of epilepsy and…”
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Hypoxia-induced angiogenesis is increased by the controlled release of deferoxiamine from gelatin hydrogels by Saito, Takashi, Tabata, Yasuhiko

“…The objective of this study is to design biodegradable hydrogels for the controlled release of deferoxiamine (DFO) and evaluate their biological activity. When…”
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