Search Results - "TAKAMORI, Yasushi"
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Granulysin Produced by Uterine Natural Killer Cells Induces Apoptosis of Extravillous Trophoblasts in Spontaneous Abortion
Published in The American journal of pathology (01-09-2008)“…Immune changes are known to occur in recurrent spontaneous abortion, but it is unclear whether either maternal natural killer (NK) cells or T cells attack…”
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Granulysin in human serum as a marker of cell‐mediated immunity
Published in European journal of immunology (01-07-2003)“…Granulysin is a cytolytic granule protein of natural killer (NK) cells and cytotoxic T lymphocytes (CTL) with a broad range of antimicrobial and tumoricidal…”
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Development of therapeutic and prophylactic vaccine against Tuberculosis using monkey and transgenic mice models
Published in Human vaccines (01-01-2011)“…[Purpose] BCG is not efficacious against M. tuberculosis (TB) in adult. Therefore, novel TB vaccines were established by using three kinds of animal models…”
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Granulysin induces cell death with nuclear accumulation
Published in Journal of medical and dental sciences (01-03-2005)“…Exogenously added granulysin was reported to kill mammalian target cells. The sites of actions and molecular mechanisms of granulysin in target cell killing,…”
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Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
Published in The Journal of experimental medicine (15-01-2001)“…Prostaglandin (PG)D2, which has long been implicated in allergic diseases, is currently considered to elicit its biological actions through the DP receptor…”
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Efficacy of Brazilian Propolis against Herpes Simplex Virus Type 1 Infection in Mice and Their Modes of Antiherpetic Efficacies
Published in Evidence-based complementary and alternative medicine (01-01-2011)“…Ethanol extracts (AF-06, 07, and 08, 10 mg/kg) of Brazilian propolis were administered orally to cutaneously herpes simplex virus type 1 (HSV-1)-infected mice…”
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Constituents of the Leaves of Woodfordia fruticosa KURZ. I : Isolation, Structure, and Proton and Carbon-13 Nuclear Magnetic Resonance Signal Assignments of Woodfruticosin (Woodfordin C), an Inhibitor of Deoxyribonucleic Acid Topoisomerase II
Published in Chemical & pharmaceutical bulletin (1990)“…Woodfruticosin (woodfordin C), a new cyclic dimeric hydrolyzable tannin having an inhibitory activity toward deoxyribonucleic acid (DNA) topoisomerase II, has…”
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Novel therapeutic vaccines [(HSP65 + IL-12)DNA-, granulysin- and Ksp37-vaccine] against tuberculosis and synergistic effects in the combination with chemotherapy
Published in Human vaccines & immunotherapeutics (01-03-2013)“…Purpose: Multi-drug resistant tuberculosis (MDR-TB) and extremely drug resistant (XDR) TB are big problems in the world. We have developed novel TB therapeutic…”
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Novel Therapeutic Vaccination(granulysin DNA, adenoviral vector/IL‐6 related genes) against Tuberculosis
Published in The FASEB journal (01-04-2008)“…We have developed novel therapeutic tuberculosis (TB) vaccines: IL‐6 related genes (IL‐6 gene + IL‐6 receptor gene + gp130 gene using adenovirus vector) and…”
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Differential expression of granulysin and perforin by NK cells in cancer patients and correlation of impaired granulysin expression with progression of cancer
Published in Cancer Immunology, Immunotherapy (01-01-2002)“…Granulysin has been identified as an effector molecule co-localized with perforin in the cytotoxic granules of cytotoxic T lymphocytes and natural killer (NK)…”
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The study of novel DNA vaccines against tuberculosis: Induction of pathogen-specific CTL in the mouse and monkey models of tuberculosis
Published in Human vaccines & immunotherapeutics (01-03-2013)“…Results: HSP65 + IL-12 DNA vaccine showed higher protective efficacy compared with BCG in both mouse and monkey models of TB. It induced the TB-specific CTL in…”
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A Preadipocyte Clonal Line from Bovine Intramuscular Adipose Tissue: Nonexpression of GLUT-4 Protein during Adipocyte Differentiation
Published in Biochemical and biophysical research communications (15-08-1995)“…A clonal bovine intramuscular preadipocyte (BIP) line has been established from the intramuscular white adipose tissue of the M. longissimus thoracis in each…”
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Woodfruticosin (woodfordin C), a new inhibitor of DNA topoisomerase II. Experimental antitumor activity
Published in Biochemical pharmacology (17-11-1992)“…Woodfruticosin (woodfordin C) (WFC), a new inhibitor of DNA topoisomerase II (topo-II), was isolated from methanol extract of Woodfordia fruticosa Kurz…”
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Constituents of the Leaves of Woodfordia fruticosa KURZ. I
Published in Chemical & pharmaceutical bulletin (01-10-1990)“…Woodfruticosin (woodfordin C), a new cyclic dimeric hydrolyzable tannin having an inhibitory activity toward deoxyribonucleic acid (DNA) topoisomerase II, has…”
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Studies on the Constituents of Acanthopanax sciadophylloides FR. et SAV. Leaves
Published in YAKUGAKU ZASSHI (25-03-1989)“…In fresh leaves of Acanthopanax sciadophylloides FR. et SAV. collected in June, the following substances were identified : (-)-β-caryophyllene,…”
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