Search Results - "TAKAHASHI, Rei"
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The Ang III/AT2R Pathway Enhances Glucose Uptake by Improving GLUT1 Expression in 3T3-L1 Adipocytes
Published in Biological & pharmaceutical bulletin (01-07-2021)“…Angiotensin III (Ang III) is a heptapeptide derived from Ang II that has been confirmed as the preferred agonist of angiotensin II type 2 receptor (AT2R)…”
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Intraperitoneal transfer of microRNA‐29b‐containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer
Published in Cancer science (01-07-2023)“…Small extracellular vesicles (sEV) contain various microRNAs (miRNAs) and play crucial roles in the tumor metastatic process. Although miR‐29b levels in…”
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3
Analysis of the high-dose-range radioresistance of prostate cancer cells, including cancer stem cells, based on a stochastic model
Published in Journal of radiation research (01-05-2019)“…Abstract In radiotherapy, cancer stem cells (CSCs) are well recognized as one of the radioresistant cell types. Even in a small subpopulation, CSCs may have an…”
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MCAM+CD161- Th17 Subset Expressing CD83 Enhances Tc17 Response in Psoriasis
Published in The Journal of immunology (1950) (15-06-2023)“…Recent studies have highlighted the pathogenic roles of IL-17-producing CD8+ T cells (T-cytotoxic 17 [Tc17]) in psoriasis. However, the underlying mechanisms…”
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5
EEG resting-state networks in Alzheimer’s disease associated with clinical symptoms
Published in Scientific reports (09-03-2023)“…Alzheimer’s disease (AD) is a progressive neuropsychiatric disease affecting many elderly people and is characterized by progressive cognitive impairment of…”
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6
Vagus nerve signal has an inhibitory influence on the development of peritoneal metastasis in murine gastric cancer
Published in Scientific reports (03-04-2024)“…The vagus nerve is the only pathway for transmitting parasympathetic signals between the brain and thoracoabdominal organs, thereby exhibiting…”
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4-Methylumbelliferone administration enhances radiosensitivity of human fibrosarcoma by intercellular communication
Published in Scientific reports (15-04-2021)“…Hyaluronan synthesis inhibitor 4-methylumbelliferone (4-MU) is a candidate of radiosensitizers which enables both anti-tumour and anti-metastasis effects in…”
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Role of Cancer Stem-like Cells in the Process of Invasion and Mesenchymal Transformation by a Reconstituted Triple-negative Breast Cancer Cell Population Resistant to p53-induced Apoptosis
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (28-10-2022)“…We investigated the role of cancer stem cells (CSCs) in a population of triple-negative breast cancer (TNBC) cells that are resistant to apoptosis. A human…”
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Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice
Published in Cellular immunology (01-06-2016)“…•Peritoneal resident macrophages from aged mice were pre-activated.•The phenotype of peritoneal resident macrophages from aged mice was M1-like.•The phagocytic…”
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A case of rapidly progressing sarcomatous intrahepatic cholangiocarcinoma with suddenly appearing lymph node metastasis
Published in Surgical case reports (08-01-2024)“…Background The sarcomatous variant of carcinoma is relatively rare in intrahepatic cholangiocarcinoma (ICC). Sarcomatous ICC (SICC) is associated with a poorer…”
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Molecular analysis of jejunal, ileal, caecal and recto-sigmoidal human colonic microbiota using 16S rRNA gene libraries and terminal restriction fragment length polymorphism
Published in Journal of medical microbiology (01-11-2005)“…1 Microbe Division/Japan Collection of Microorganisms, RIKEN BioResource Center, Saitama 351-0198, Japan 2 Departments of Pathology and Tumor Biology, Graduate…”
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A novel animal model of Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis in humanized mice
Published in Blood (26-05-2011)“…EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH) is a rare yet devastating disorder caused by EBV infection in humans. However, the mechanism of…”
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13
Stem-like Human Breast Cancer Cells Initiate Vasculogenic Mimicry on Matrigel
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (20-12-2018)“…Vasculogenic mimicry (VM), referring to vasculogenic structures lined by tumor cells, can be distinguished from angiogenesis, and is responsible for the…”
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14
RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity
Published in Nature neuroscience (01-07-2007)“…We report that during cortical development in the mouse embryo, reversion-inducing cysteine-rich protein with Kazal motifs (RECK) critically regulates Notch…”
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15
Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice
Published in Geriatrics & gerontology international (01-01-2016)“…Aim Secondary necrotic cells generated in vivo induce inflammatory responses; for example, the production of macrophage inflammatory protein‐2 (MIP‐2) and…”
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4-methylumbelliferone inhibits clonogenic potency by suppressing high molecular weight-hyaluronan in fibrosarcoma cells
Published in Oncology letters (01-04-2020)“…The inflammatory response is closely associated with cancer cell survival. It has been reported that inflammatory signaling cascades promote tumor survival and…”
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The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis
Published in Cell (14-12-2001)“…Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling. We previously found that a membrane-anchored glycoprotein, RECK,…”
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Induced Expression of Cancer Stem Cell Markers ALDH1A3 and Sox-2 in Hierarchical Reconstitution of Apoptosis-resistant Human Breast Cancer Cells
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-2016)“…We established an experimental system that can induce p53-dependent apoptosis by doxycycline treatment to analyze characteristics of the apoptosis-resistant…”
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Effects of Helicobacter pylori Infection on Gastric Parietal Cells and E-cadherin in Mongolian Gerbils
Published in Journal of Pharmacological Sciences (2013)“…Atrophic gastritis caused by infection with Helicobacter pylori is characterized by parietal cell loss, which is a main risk factor for gastric cancer…”
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Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition
Published in iScience (21-02-2020)“…Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains…”
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