Search Results - "TAKAHASHI, Nagahide"
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Roles of glial cells in schizophrenia: Possible targets for therapeutic approaches
Published in Neurobiology of disease (01-05-2013)“…Abstract Glial cells consisting of oligodendrocytes, astrocytes, microglia, and NG2 positive cells are major cell populations in the central nervous system,…”
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Peripheral biomarkers of attention-deficit hyperactivity disorder: Current status and future perspective
Published in Journal of psychiatric research (01-05-2021)“…Attention-deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by a persistent pattern of inattention,…”
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3
The genetic architecture of schizophrenia: review of large-scale genetic studies
Published in Journal of human genetics (01-03-2023)“…Schizophrenia is a complex and often chronic psychiatric disorder with high heritability. Diagnosis of schizophrenia is still made clinically based on…”
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4
Efficacy and safety of fixed doses of intranasal Esketamine as an add-on therapy to Oral antidepressants in Japanese patients with treatment-resistant depression: a phase 2b randomized clinical study
Published in BMC psychiatry (25-10-2021)“…Esketamine nasal spray (Spravato) in conjunction with oral antidepressants (ADs) is approved in the European Union, United States, and other markets for…”
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Perfluorooctanoate and perfluorooctane sulfonate in umbilical cord blood and child cognitive development: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)
Published in Environment international (01-05-2022)“…[Display omitted] •We investigated prenatal exposure to PFAS in association with child ASD.•Prenatal PFOA and PFNA were associated with increased risk of…”
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Interleukin-23 levels in umbilical cord blood are associated with neurodevelopmental trajectories in infancy
Published in PloS one (09-04-2024)“…Our previous study, which aimed to understand the early neurodevelopmental trajectories of children with and without neurodevelopmental disorders, identified…”
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Identification of neurodevelopmental transition patterns from infancy to early childhood and risk factors predicting descending transition
Published in Scientific reports (21-03-2022)“…It is unclear whether neurodevelopmental progress from infancy to early childhood remains stable. Moreover, little is known about the risk factors, if any,…”
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8
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication
Published in Molecular autism (17-12-2010)“…SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key functional elements to the PSD and to the…”
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Outdoor Play as a Mitigating Factor in the Association Between Screen Time for Young Children and Neurodevelopmental Outcomes
Published in JAMA pediatrics (01-03-2023)“…Whether the association between higher screen time in infancy and later suboptimal neurodevelopment can be mitigated by frequency of outdoor play is unknown…”
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Long-term effect of persistent postpartum depression on children's psychological problems in childhood
Published in Journal of affective disorders (15-05-2022)“…Maternal postpartum depression (PPD) is a well-established risk factor for psychological problems in children; however, little is known about the sustained…”
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11
Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy
Published in Translational psychiatry (17-08-2020)“…Attention deficit hyperactive disorder (ADHD) is a highly heritable neurodevelopmental disorder, and excessive daytime sleepiness is frequently observed in…”
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12
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity
Published in Nature neuroscience (01-09-2012)“…The authors show that chronic treatment with antipsychotic drugs decreases expression of mGlu2 and histone acetylation at its promoter in frontal cortex. This…”
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13
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice
Published in PloS one (10-08-2012)“…Copy number variation (CNV) at the 15q11.2 region, which includes a gene that codes for CYFIP1 (cytoplasmic FMR1 interacting protein 1), has been implicated in…”
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14
Assessment of executive functions using a 3D-video game in children and adolescents with ADHD
Published in Frontiers in psychiatry (22-08-2024)“…Executive functions are important factors that affect the well-being of children with ADHD. Therefore, inclusion of a convenient assessment of executive…”
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Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g
Published in BMC medicine (24-09-2021)“…Background Both genetic and pre- and perinatal factors, including birth weight, have been implicated in the onset of attention deficit hyperactivity disorder…”
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16
Perceived Social Support Partially Mediates the Impact of Temperament and Character on Postpartum Depression
Published in Frontiers in psychiatry (24-01-2022)“…Temperament and character of pregnant women, especially harm avoidance (HA) and self-directedness (SD) have been identified as risk factors for postpartum…”
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Autism spectrum disorder comorbid with obsessive compulsive disorder and eating disorder in a woman with NBEA deletion
Published in Psychiatry and clinical neurosciences (01-01-2022)Get full text
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18
Sex differences in neurodevelopmental trajectories in children with different levels of autistic traits
Published in Psychiatry and clinical neurosciences (01-05-2023)“…Aim Little is known about early manifestations of autism spectrum disorders (ASD) in females, including those who may be overlooked by the current diagnostic…”
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19
Strong synaptic transmission impact by copy number variations in schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-2010)“…Schizophrenia is a psychiatric disorder with onset in late adolescence and unclear etiology characterized by both positive and negative symptoms, as well as…”
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20
Early temperament as a predictor of language skills at 40 months
Published in BMC pediatrics (21-01-2022)“…Mastering language involves the development of expressive and receptive skills among children. While it has been speculated that early temperament plays a role…”
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