Search Results - "TAHER, Ali"
-
1
Thalassaemia
Published in The Lancet (British edition) (13-01-2018)“…Inherited haemoglobin disorders, including thalassaemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of…”
Get full text
Journal Article -
2
How I manage medical complications of β-thalassemia in adults
Published in Blood (25-10-2018)“…The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in…”
Get full text
Journal Article -
3
β-Thalassemias
Published in The New England journal of medicine (25-02-2021)“…Defective synthesis of the β-globin chain causes recessively inherited disorders characterized by inadequate hemoglobin production and chronic anemia…”
Get full text
Journal Article -
4
Iron overload in thalassemia: different organs at different rates
Published in Hematology (08-12-2017)“…Thalassemic disorders lie on a phenotypic spectrum of clinical severity that depends on the severity of the globin gene mutation and coinheritance of other…”
Get full text
Journal Article -
5
Beta Thalassemia: New Therapeutic Options Beyond Transfusion and Iron Chelation
Published in Drugs (New York, N.Y.) (01-07-2020)“…Hemoglobinopathies are among the most common monogenic diseases worldwide. Approximately 1–5% of the global population are carriers for a genetic thalassemia…”
Get full text
Journal Article -
6
Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management
Published in International journal of molecular sciences (08-01-2018)“…Patients with non-transfusion-dependent thalassemia (NTDT) experience many clinical complications despite their independence from frequent transfusions…”
Get full text
Journal Article -
7
Assessment of X-ray films and image quality in diagnostic radiology departments of teaching hospitals in Iraq
Published in Radiation effects and defects in solids (03-03-2024)“…Background: Patients undergo repeated X-ray examinations after their initial X-ray radiographs are rejected due to poor image quality. Reject analysis in…”
Get full text
Journal Article -
8
Iron deficiency beyond erythropoiesis: should we be concerned?
Published in Current medical research and opinion (02-01-2018)“…Objective: To consider the key implications of iron deficiency for biochemical and physiological functions beyond erythropoiesis. Methods: PubMed was searched…”
Get full text
Journal Article -
9
A paradigm shift on beta-thalassaemia treatment: How will we manage this old disease with new therapies?
Published in Blood reviews (01-07-2018)“…Beta-thalassaemia causes defective haemoglobin synthesis leading to ineffective erythropoiesis, chronic haemolytic anaemia, and subsequent clinical…”
Get full text
Journal Article -
10
Luspatercept for β-thalassemia: beyond red blood cell transfusions
Published in Expert opinion on biological therapy (02-11-2021)“…Red blood cell transfusions and iron chelation therapy are the cornerstone of treatment for β-thalassemia, with allogeneic hematopoietic stem cell…”
Get more information
Journal Article -
11
Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management
Published in American journal of hematology (01-10-2017)“…Iron deficiency, even in the absence of anemia, can be debilitating, and exacerbate any underlying chronic disease, leading to increased morbidity and…”
Get full text
Journal Article -
12
Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia
Published in European spine journal (01-06-2010)“…Ineffective erythropoiesis in patients with thalassemia intermedia drives extramedullary hematopoietic tumor formation in several parts of the body. Paraspinal…”
Get full text
Journal Article -
13
Thalassaemia—A global view
Published in British journal of haematology (01-04-2023)“…Summary The thalassaemias are a group of genetic disorders of haemoglobin which are endemic in the tropics but are now found worldwide due to migration. Basic…”
Get full text
Journal Article -
14
Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study
Published in The Lancet (British edition) (15-10-2011)“…Summary Background Preoperative anaemia is associated with adverse outcomes after cardiac surgery but outcomes after non-cardiac surgery are not well…”
Get full text
Journal Article -
15
How I treat non-transfusion-dependent β-thalassemia
Published in Blood (14-09-2023)“…[Display omitted] The intricate interplay of anemia and iron overload under the pathophysiological umbrella of ineffective erythropoiesis in…”
Get full text
Journal Article -
16
Hepatocellular carcinoma as an emerging morbidity in the thalassemia syndromes: A comprehensive review
Published in Cancer (01-03-2017)“…The incidence of hepatocellular carcinoma (HCC) in patients with thalassemia is on the rise. The 2 well recognized HCC risk factors in thalassemia are iron…”
Get full text
Journal Article -
17
Variations in hemoglobin level and morbidity burden in non-transfusion-dependent β-thalassemia
Published in Annals of hematology (01-07-2021)Get full text
Journal Article -
18
2021 update on clinical trials in β‐thalassemia
Published in American journal of hematology (01-11-2021)“…The treatment landscape for patients with β‐thalassemia is witnessing a swift evolution, yet several unmet needs continue to persist. Patients with…”
Get full text
Journal Article -
19
Ineffective Erythropoiesis: Anemia and Iron Overload
Published in Hematology/oncology clinics of North America (01-04-2018)“…Stress erythropoiesis (SE) is characterized by an imbalance in erythroid proliferation and differentiation under increased demands of erythrocyte generation…”
Get full text
Journal Article -
20
Management of luspatercept therapy in patients with transfusion‐dependent β‐thalassaemia
Published in British journal of haematology (01-06-2023)“…Summary Patients with transfusion‐dependent β‐thalassaemia require lifelong, regular red blood cell transfusions for survival; however, frequent blood…”
Get full text
Journal Article