Search Results - "TACCONI, M"

Solution of Heliospheric Propagation: Unveiling the Local Interstellar Spectra of Cosmic-ray Species by Boschini, M. J., Torre, S. Della, Gervasi, M., Grandi, D., Jóhannesson, G., Kachelriess, M., Vacca, G. La, Masi, N., Moskalenko, I. V., Orlando, E., Ostapchenko, S. S., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Local interstellar spectra (LIS) for protons, helium, and antiprotons are built using the most recent experimental results combined with state-of-the-art…”
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HelMod in the Works: From Direct Observations to the Local Interstellar Spectrum of Cosmic-Ray Electrons by Boschini, M. J., Torre, S. Della, Gervasi, M., Grandi, D., Jóhannesson, G., La Vacca, G., Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…The local interstellar spectrum (LIS) of cosmic-ray (CR) electrons for the energy range 1 MeV to 1 TeV is derived using the most recent experimental results…”
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A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics by Chaikuad, Apirat, M C Tacconi, Eliana, Zimmer, Jutta, Liang, Yanke, Gray, Nathanael S, Tarsounas, Madalena, Knapp, Stefan

“…Crystallographic analysis depicting the interaction of the kinase inhibitor SCH772984 with ERK1/2 reveals a unique binding pocket distinct from off-targets…”
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Deciphering the Local Interstellar Spectra of Secondary Nuclei with the Galprop/Helmod Framework and a Hint for Primary Lithium in Cosmic Rays by Boschini, M. J., Torre, S. Della, Gervasi, M., Grandi, D., Jøhannesson, G., Vacca, G. La, Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Local interstellar spectra (LIS) of secondary cosmic-ray (CR) nuclei, lithium, beryllium, boron, and partially secondary nitrogen, are derived in the rigidity…”
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Deciphering the Local Interstellar Spectra of Primary Cosmic-Ray Species with HelMod by Boschini, M. J., Torre, S. Della, Gervasi, M., Grandi, D., Jóhannesson, G., Vacca, G. La, Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Local interstellar spectra (LIS) of primary cosmic ray (CR) nuclei, such as helium, oxygen, and mostly primary carbon are derived for the rigidity range from…”
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The Discovery of a Low-energy Excess in Cosmic-Ray Iron: Evidence of the Past Supernova Activity in the Local Bubble by Boschini, M. J., Della Torre, S., Gervasi, M., Grandi, D., Jóhannesson, G., La Vacca, G., Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Since its launch, the Alpha Magnetic Spectrometer-02 (AMS-02) has delivered outstanding quality measurements of the spectra of cosmic-ray (CR) species ( , ,…”
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A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells by Dagg, Rebecca A., Zonderland, Gijs, Lombardi, Emilia Puig, Rossetti, Giacomo G., Groelly, Florian J., Barroso, Sonia, Tacconi, Eliana M. C., Wright, Benjamin, Lockstone, Helen, Aguilera, Andrés, Halazonetis, Thanos D., Tarsounas, Madalena

“…BRCA1 or BRCA2 germline mutations predispose to breast, ovarian and other cancers. High-throughput sequencing of tumour genomes revealed that oncogene…”
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A Hint of a Low-energy Excess in Cosmic-Ray Fluorine by Boschini, M. J., Della Torre, S., Gervasi, M., Grandi, D., Jóhannesson, G., La Vacca, G., Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Abstract Since its launch, the Alpha Magnetic Spectrometer–02 (AMS-02) has delivered outstanding quality measurements of the spectra of cosmic-ray (CR) species…”
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Spectra of Cosmic-Ray Sodium and Aluminum and Unexpected Aluminum Excess by Boschini, M. J., Torre, S. Della, Gervasi, M., Grandi, D., Jóhannesson, G., La Vacca, G., Masi, N., Moskalenko, I. V., Pensotti, S., Porter, T. A., Quadrani, L., Rancoita, P. G., Rozza, D., Tacconi, M.

“…Abstract Since its launch, the Alpha Magnetic Spectrometer-02 (AMS-02) has delivered outstanding quality measurements of the spectra of cosmic-ray (CR)…”
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On the forward‐backward‐in‐time approach for Monte Carlo solution of Parker's transport equation: One‐dimensional case by Bobik, P., Boschini, M. J., Della Torre, S., Gervasi, M., Grandi, D., La Vacca, G., Pensotti, S., Putis, M., Rancoita, P. G., Rozza, D., Tacconi, M., Zannoni, M.

“…The cosmic rays propagation inside the heliosphere is well described by a transport equation introduced by Parker in 1965. To solve this equation, several…”
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Bronchiectasis as long-term complication of acute fire smoke inhalation? by Rizzato, S., Tacconi, M., Andrisani, D., Luppi, F., Clini, E., Cerri, S.

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Review of Adjuvant Therapies in Renal Cell Carcinoma: Evidence to Date by Tacconi, Eliana MC, Tuthill, Mark, Protheroe, Andrew

“…In 2018, there were 400,000 new cases of renal cell carcinoma (RCC) globally, with 175,000 deaths attributable to the disease. Three quarters of patients have…”
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SYSTEMATIC INVESTIGATION OF SOLAR MODULATION OF GALACTIC PROTONS FOR SOLAR CYCLE 23 USING A MONTE CARLO APPROACH WITH PARTICLE DRIFT EFFECTS AND LATITUDINAL DEPENDENCE by BOBIK, P, BOELLA, G, TACCONI, M, BOSCHINI, M. J, CONSOLANDI, C, DELLA TORRE, S, GERVASI, M, GRANDI, D, KUDELA, K, PENSOTTI, S, RANCOITA, P. G

“…A propagation model of galactic cosmic protons through the heliosphere was implemented using a two-dimensional Monte Carlo approach to determine the…”
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How homologous recombination maintains telomere integrity by Tacconi, Eliana M. C., Tarsounas, Madalena

“…Telomeres protect the ends of linear chromosomes against loss of genetic information and inappropriate processing as damaged DNA and are therefore crucial to…”
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Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma by McGowan, Daniel R., Skwarski, Michael, Bradley, Kevin M., Campo, Leticia, Fenwick, John D., Gleeson, Fergus V., Green, Marcus, Horne, Amanda, Maughan, Timothy S., McCole, Mark G., Mohammed, Seid, Muschel, Ruth J., Ng, Stasya M., Panakis, Niki, Prevo, Remko, Strauss, Victoria Y., Stuart, Robert, Tacconi, Eliana M.C., Vallis, Katherine A., McKenna, W. Gillies, Macpherson, Ruth E., Higgins, Geoff S.

“…Pre-clinically, phosphoinositide 3-kinase (PI3K) inhibition radiosensitises tumours by increasing intrinsic radiosensitivity and by reducing tumour hypoxia. We…”
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PHOTON-INDUCED EVOLUTIONARY RATES OF LiHe+ (1Σ+) IN EARLY UNIVERSE FROM ACCURATE QUANTUM COMPUTATIONS by BOVINO, S, TACCONI, M, GIANTURCO, F. A

“…The radiative association rates for the formation of LiHe+ molecules in their ground electronic state have been calculated employing an accurate ab initio…”
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Cold Chemistry with Ionic Partners: Quantum Features of HeH+(1Σ) with H(1S) at Ultralow Energies by Bovino, S, Tacconi, M, Gianturco, F. A

“…Quantum reactive calculations are presented for an ion-atom reaction involving the HeH+cation and its destruction via a barrierless interaction with H atoms…”
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The economic burden of cancer, coronary heart disease, dementia, and stroke in England in 2018, with projection to 2050: an evaluation of two cohort studies by Landeiro, Filipa, Harris, Callum, Groves, David, O’Neill, Samuel, Jandu, Kuljinder Singh, Tacconi, Eliana M C, Field, Samantha, Patel, Nileema, Göpfert, Anya, Hagson, Hannes, Leal, José, Luengo-Fernández, Ramón

“…Cancer, coronary heart disease, dementia, and stroke are major contributors to morbidity and mortality in England. We aimed to assess the economic burden…”
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BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity by Tacconi, Eliana MC, Lai, Xianning, Folio, Cecilia, Porru, Manuela, Zonderland, Gijs, Badie, Sophie, Michl, Johanna, Sechi, Irene, Rogier, Mélanie, Matía García, Verónica, Batra, Ankita Sati, Rueda, Oscar M, Bouwman, Peter, Jonkers, Jos, Ryan, Anderson, Reina‐San‐Martin, Bernardo, Hui, Joannie, Tang, Nelson, Bruna, Alejandra, Biroccio, Annamaria, Tarsounas, Madalena

“…Maintenance of genome integrity requires the functional interplay between Fanconi anemia (FA) and homologous recombination (HR) repair pathways. Endogenous…”
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Chlorambucil targets BRCA1/2‐deficient tumours and counteracts PARP inhibitor resistance by Tacconi, Eliana MC, Badie, Sophie, De Gregoriis, Giuliana, Reisländer, Timo, Lai, Xianning, Porru, Manuela, Folio, Cecilia, Moore, John, Kopp, Arnaud, Baguña Torres, Júlia, Sneddon, Deborah, Green, Marcus, Dedic, Simon, Lee, Jonathan W, Batra, Ankita Sati, Rueda, Oscar M, Bruna, Alejandra, Leonetti, Carlo, Caldas, Carlos, Cornelissen, Bart, Brino, Laurent, Ryan, Anderson, Biroccio, Annamaria, Tarsounas, Madalena

“…Due to compromised homologous recombination (HR) repair, BRCA1‐ and BRCA2‐ mutated tumours accumulate DNA damage and genomic rearrangements conducive of tumour…”
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