Search Results - "TABATA, Mitsuhisa"

Role of Endothelial Cell–Derived Angptl2 in Vascular Inflammation Leading to Endothelial Dysfunction and Atherosclerosis Progression by Horio, Eiji, Kadomatsu, Tsuyoshi, Miyata, Keishi, Arai, Yasumichi, Hosokawa, Kentaro, Doi, Yasufumi, Ninomiya, Toshiharu, Horiguchi, Haruki, Endo, Motoyoshi, Tabata, Mitsuhisa, Tazume, Hirokazu, Tian, Zhe, Takahashi, Otowa, Terada, Kazutoyo, Takeya, Motohiro, Hao, Hiroyuki, Hirose, Nobuyoshi, Minami, Takashi, Suda, Toshio, Kiyohara, Yutaka, Ogawa, Hisao, Kaikita, Koichi, Oike, Yuichi

“…OBJECTIVE—Cardiovascular disease (CVD), the most common morbidity resulting from atherosclerosis, remains a frequent cause of death. Efforts to develop…”
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Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance by Tabata, Mitsuhisa, Kadomatsu, Tsuyoshi, Fukuhara, Shigetomo, Miyata, Keishi, Ito, Yasuhiro, Endo, Motoyoshi, Urano, Takashi, Zhu, Hui Juan, Tsukano, Hiroto, Tazume, Hirokazu, Kaikita, Koichi, Miyashita, Kazuya, Iwawaki, Takao, Shimabukuro, Michio, Sakaguchi, Kazuhiko, Ito, Takaaki, Nakagata, Naomi, Yamada, Tetsuya, Katagiri, Hideki, Kasuga, Masato, Ando, Yukio, Ogawa, Hisao, Mochizuki, Naoki, Itoh, Hiroshi, Suda, Toshio, Oike, Yuichi

“…Recent studies of obesity have provided new insights into the mechanisms underlying insulin resistance and metabolic dysregulation. Numerous efforts have been…”
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Angiopoietin-Like Proteins: Potential Therapeutic Targets for Metabolic Syndrome and Cardiovascular Disease by Oike, Yuichi, Tabata, Mitsuhisa

“…Recent major increases in obesity and related metabolic diseases (known as the metabolic syndrome (MetS)) because of sedentary lifestyles and overnutrition in…”
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Adipose Tissue CLK2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting by Hatting, Maximilian, Rines, Amy K., Luo, Chi, Tabata, Mitsuhisa, Sharabi, Kfir, Hall, Jessica A., Verdeguer, Francisco, Trautwein, Christian, Puigserver, Pere

“…A promising approach to treating obesity is to increase diet-induced thermogenesis in brown adipose tissue (BAT), but the regulation of this process remains…”
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USP7 Attenuates Hepatic Gluconeogenesis Through Modulation of FoxO1 Gene Promoter Occupancy by Hall, Jessica A, Tabata, Mitsuhisa, Rodgers, Joseph T, Puigserver, Pere

“…Hepatic forkhead protein FoxO1 is a key component of systemic glucose homeostasis via its ability to regulate the transcription of rate-limiting enzymes in…”
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Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice by Tomita, Kengo, Oike, Yuichi, Teratani, Toshiaki, Taguchi, Takashi, Noguchi, Masaaki, Suzuki, Takahiro, Mizutani, Akiko, Yokoyama, Hirokazu, Irie, Rie, Sumimoto, Hidetoshi, Takayanagi, Atsushi, Miyashita, Kiichi, Akao, Masaki, Tabata, Mitsuhisa, Tamiya, Gen, Ohkura, Tamiko, Hibi, Toshifumi

“…It is unclear how hepatic adiponectin resistance and sensitivity mediated by the adiponectin receptor, AdipoR2, contributes to the progression of nonalcoholic…”
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Efficacy of a Moderately Low Carbohydrate Diet in a 36-Month Observational Study of Japanese Patients with Type 2 Diabetes by Sanada, Mariko, Kabe, Chinatsu, Hata, Hisa, Uchida, Junichi, Inoue, Gaku, Tsukamoto, Yoko, Yamada, Yoshifumi, Irie, Junichiro, Tabata, Shogo, Tabata, Mitsuhisa, Yamada, Satoru

“…We previously showed that a non-calorie-restricted, moderately low-carbohydrate diet (mLCD) is more effective than caloric restriction for glycemic and lipid…”
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A comparison study of patient ratings and safety of 32- and 34-gauge insulin pen needles by Yamada, Satoru, Yamada, Yoshifumi, Tsukamoto, Yoko, Tabata, Mitsuhisa, Irie, Junichiro

“…Objective Our aims were to compare diabetic patients’ evaluations of straight 32- and tapered 34-gauge 4-mm needles for usability and preference as well as the…”
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Angiopoietins contribute to lung development by regulating pulmonary vascular network formation by Hato, Tai, Kimura, Yoshishige, Morisada, Tohru, Koh, Gou Young, Miyata, Keishi, Tabata, Mitsuhisa, Kadomatsu, Tsuyoshi, Endo, Motoyoshi, Urano, Takashi, Arai, Fumio, Araki, Kimi, Suda, Toshio, Kobayashi, Koichi, Oike, Yuichi

“…Angiopoietin (Ang) signaling through the Tie2 receptor regulates vasculature. The role of Ang signaling in pulmonary hypertension is well investigated, but its…”
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Nifedipine increases energy expenditure by increasing PGC-1α expression in skeletal muscle by Tian, Zhe, Miyata, Keishi, Tabata, Mitsuhisa, Yano, Masato, Tazume, Hirokazu, Aoi, Jun, Takahashi, Otowa, Araki, Kimi, Kawasuji, Michio, Oike, Yuichi

“…Nifedipine, an L-type calcium (Ca) channel blocker, is one of the most widely used Ca channel-blocking medications for hypertension. Previous studies have…”
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Effects of Pretreatment with Low-dose Metformin on Metabolic Parameters and Weight Gain by Pioglitazone in Japanese Patients with Type 2 Diabetes by Kawai, Toshihide, Funae, Osamu, Shimada, Akira, Tabata, Mitsuhisa, Hirata, Takumi, Atsumi, Yoshihito, Itoh, Hiroshi

“…Objective We investigated whether or not "low dose" metformin could prevent weight gain induced by pioglitazone. Research Design and Methods Sixty-nine…”
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Angiopoietin‐like proteins: emerging targets for treatment of obesity and related metabolic diseases by Kadomatsu, Tsuyoshi, Tabata, Mitsuhisa, Oike, Yuichi

“…Obesity and related metabolic diseases, such as type 2 diabetes, hypertension and hyperlipidemia are an increasingly prevalent medical and social problem in…”
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The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism by Hato, Tai, Tabata, Mitsuhisa, Oike, Yuichi

“…Recently, a family of proteins structurally similar to the angiogenic regulating factors angiopoietins was identified and designated “angiopoietin-like…”
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AGF/Angpt16 by Tabata, Mitsuhisa, Oike, Yuichi

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Effects of the angiotensin II type 1 receptor antagonist candesartan, compared with angiotensin-converting enzyme inhibitors, on the urinary excretion of albumin and type IV collagen in patients with diabetic nephropathy by Sato, Atsuhisa, Tabata, Mitsuhisa, Hayashi, Koichi, Saruta, Takao

“…We previously reported that the angiotensin II type 1 receptor antagonist candesartan was effective in reducing blood pressure and microalbuminuria in…”
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Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1 by Iwabu, Masato, Yamauchi, Toshimasa, Okada-Iwabu, Miki, Sato, Koji, Nakagawa, Tatsuro, Funata, Masaaki, Yamaguchi, Mamiko, Namiki, Shigeyuki, Nakayama, Ryo, Tabata, Mitsuhisa, Ogata, Hitomi, Kubota, Naoto, Takamoto, Iseki, Hayashi, Yukiko K., Yamauchi, Naoko, Waki, Hironori, Fukayama, Masashi, Nishino, Ichizo, Tokuyama, Kumpei, Ueki, Kohjiro, Oike, Yuichi, Ishii, Satoshi, Hirose, Kenzo, Shimizu, Takao, Touhara, Kazushige, Kadowaki, Takashi

“…Adiponectin is an anti-diabetic adipokine. Its receptors possess a seven-transmembrane topology with the amino terminus located intracellularly, which is the…”
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Oleic Acid Stimulates Complete Oxidation of Fatty Acids through Protein Kinase A-dependent Activation of SIRT1-PGC1α Complex by Lim, Ji-Hong, Gerhart-Hines, Zachary, Dominy, John E., Lee, Yoonjin, Kim, Sungjin, Tabata, Mitsuhisa, Xiang, Yang K., Puigserver, Pere

“…Fatty acids are essential components of the dynamic lipid metabolism in cells. Fatty acids can also signal to intracellular pathways to trigger a broad range…”
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Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/− mice by Morita, Masahiro, Oike, Yuichi, Nagashima, Takeshi, Kadomatsu, Tsuyoshi, Tabata, Mitsuhisa, Suzuki, Toru, Nakamura, Takahisa, Yoshida, Nobuaki, Okada, Mariko, Yamamoto, Tadashi

“…Obesity is a life‐threatening factor and is often associated with dysregulation of gene expression. Here, we show that the CNOT3 subunit of the CCR4–NOT…”
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Two Cases in which an Abnormal Hemoglobin (Hb Kamakura) was Identified on the Basis of an Abnormally Low Glycohemoglobin Levels by SAISHO, Yoshifumi, SAITOH, Fumitake, TABATA, Mitsuhisa, IMAFUKU, Toshio, OGIHARA, Tohru, ISSIKI, Ikuko, HATTORI, Yukio, YAMASHIRO, Yasuhiro

“…We encountered two patients with abnormally low glycohemoglobin levels in spite of normal plasma glucose levels. Since the presence of an abnormal hemoglobin…”
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Cdc2-Like Kinase 2 Suppresses Hepatic Fatty Acid Oxidation and Ketogenesis Through Disruption of the PGC-1α and MED1 Complex by TABATA, Mitsuhisa, RODGERS, Joseph T, HALL, Jessica A, YOONJIN LEE, JEDRYCHOWSKI, Mark P, GYGI, Steven P, PUIGSERVER, Pere

“…Hepatic ketogenesis plays an important role in catabolism of fatty acids during fasting along with dietary lipid overload, but the mechanisms regulating this…”
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