Search Results - "T. Kietzmann"
-
1
Effects of contextual information and stimulus ambiguity on overt visual sampling behavior
Published in Vision research (Oxford) (01-05-2015)“…•Increased information changes the initial overt visual exploration of objects.•Contextual scenes lead to shorter reaction times, yet longer fixation…”
Get full text
Journal Article -
2
-
3
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase
Published in Circulation research (06-07-2001)“…The heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1) is activated under hypoxic conditions, resulting in the upregulation of its target…”
Get full text
Journal Article -
4
Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells
Published in Biological chemistry (01-03-2004)“…Pulmonary hypertension and vascular remodeling processes are associated with oxidative stress, hypoxia and enhanced levels of thrombin and vascular endothelial…”
Get more information
Journal Article -
5
Perivenous expression of the mRNA of the three hypoxia-inducible factor α-subunits, HIF1α, HIF2α and HIF3α, in rat liver
Published in Biochemical journal (15-03-2001)Get full text
Journal Article -
6
Modulation of glucokinase expression by hypoxia-inducible factor 1 and upstream stimulatory factor 2 in primary rat hepatocytes
Published in Biological chemistry (01-03-2004)“…Glucokinase (GK) is the key enzyme of glucose utilization in liver and is localized in the less aerobic perivenous area. Until now, the O2-responsive elements…”
Get more information
Journal Article -
7
Expression patterns of erythropoietin and its receptor in the developing midbrain
Published in Anatomy and Embryology (01-03-2004)“…The expression patterns of erythropoietin (EPO) and its receptor (EPOR) were investigated in the midbrain and in adjacent parts of the synencephalon and…”
Get full text
Journal Article -
8
Reactive oxygen species in signal transduction
Published in Ukrainian biochemical journal (27-12-2013)Get full text
Journal Article -
9
Oxygen: modulator of physiological and pathophysiological processes in the liver
Published in Zeitschrift für Gastroenterologie (01-01-2006)“…Oxygen has important functions as substrate for biochemical reactions and as modulator of gene expression. In the liver, the physiologically occurring oxygen…”
Get more information
Journal Article -
10
Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression
Published in Thrombosis and haemostasis (01-06-2005)“…The p21-activated serine/threonine kinases (PAK) play an important role in a variety of cellular functions. However, their role in the smooth muscle response…”
Get more information
Journal Article -
11
Expression of hypoxia-inducible factor-1 in the cochlea of newborn rats
Published in Hearing research (01-09-2003)“…Hypoxia/ischemia is a major pathogenetic factor in the development of hearing loss. An important transcription factor involved in the signaling and adaptation…”
Get full text
Journal Article -
12
An atypical NF-kappa B-regulated pathway mediates phorbol ester-dependent Heme oxygenase-1 gene activation in monocytes
Published in Cell communication and signaling (26-02-2009)Get full text
Journal Article -
13
Serum-Free, Long-Term Cultures of Human Hepatocytes: Maintenance of Cell Morphology, Transcription Factors, and Liver-Specific Functions
Published in Biochemical and biophysical research communications (05-03-2000)“…Since human hepatocytes are available only in limited number, the development of a serum-free culture system for long-term cultivation of differentiated and…”
Get full text
Journal Article -
14
RECOMBINANT LENTIVIRUS-MEDIATED SILENCING OF ADAPTOR PROTEIN RUK/CIN85 EXPRESSION INFLUENCES BIOLOGICAL RESPONSES OF TUMOR CELLS
Published in Biotechnologia acta (01-01-2013)“…It was the aim of the present study to investigate whether inhibition of Ruk/CIN85 expression has an effect on the biological properties of the cells. In order…”
Get full text
Journal Article -
15
Modulation by oxygen of zonal gene expression in liver studied in primary rat hepatocyte cultures
Published in Cell biology and toxicology (01-07-1997)“…The different endowment with key enzymes and thus different metabolic capacities of periportal and perivenous cell types led to the model of "metabolic…”
Get full text
Journal Article -
16
Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension
Published in Molecular pharmacology (01-07-1999)“…Treatment of male rats with phenobarbital (PB) results in a perivenous and mid-zonal pattern of cytochrome P-450 (CYP)2B1 mRNA expression within the liver…”
Get more information
Journal Article -
17
Influence of ischemia/hypoxia on the HIF-1 activity and expression of hypoxia-dependent genes in the cochlea of the newborn rat
Published in HNO (01-09-2006)“…Transcription factor HIF-1 (hypoxia-inducible factor-1) regulates the expression of genes which are involved in glucose supply, growth, metabolism, redox…”
Get full text
Journal Article -
18
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures
Published in Biochemical journal (01-09-2000)“…P-Glycoprotein transporters encoded by mdr1 (multidrug resistance) genes mediate extrusion of an array of lipophilic xenobiotics from the cell. In rat liver,…”
Get full text
Journal Article -
19
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression
Published in Seminars in cell & developmental biology (01-08-2005)“…Reactive oxygen species (ROS) have long been considered as cytotoxic. However, recent evidence indicates a prominent role of ROS as signaling molecules in the…”
Get full text
Journal Article -
20
Oxygen as a regulator of serine dehydratase (SerDH) gene expression
Published in Biopolimery i kletka (2007)“…An oxygen gradient is formed in the liver due to the unidirectional blood flow from the portal vein and hepatic artery to the central vein and due to the…”
Get full text
Journal Article