Search Results - "T. H. Aldrich"

Angiopoietin-2, a Natural Antagonist for Tie2 that Disrupts In vivo Angiogenesis by Maisonpierre, Peter C., Suri, Chitra, Jones, Pamela F., Bartunkova, Sona, Wiegand, Stanley J., Radziejewski, Czeslaw, Compton, Debra, McClain, Joyce, Aldrich, Thomas H., Papadopoulos, Nick, Daly, Thomas J., Davis, Samuel, Sato, Thomas N., Yancopoulos, George D.

“…Angiogenesis is thought to depend on a precise balance of positive and negative regulation. Angiopoietin-1 (Ang1) is an angiogenic factor that signals through…”
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Ligands for EPH-Related Receptor Tyrosine Kinases That Require Membrane Attachment or Clustering for Activity by Davis, Samuel, Gale, Nicholas W., Aldrich, Thomas H., Maisonpierre, Peter C., Lhotak, Vladimir, Pawson, Tony, Goldfarb, Mitchell, Yancopoulos, George D.

“…The EPH-related transmembrane tyrosine kinases constitute the largest known family of receptor-like tyrosine kinases, with many members displaying specific…”
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The Receptor for Ciliary Neurotrophic Factor by Davis, Samuel, Aldrich, Thomas H., Valenzuela, David M., Wong, Vivien, Furth, Mark E., Squinto, Stephen P., Yancopoulos, George D.

“…Although neurotrophic factors were originally isolated on the basis of their ability to support the survival of neurons, these molecules are now thought to…”
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Released Form of CNTF Receptor α Component as a Soluble Mediator of CNTF Responses by Davis, Samuel, Aldrich, Thomas H., Ip, Nancy Y., Stahl, Neil, Scherer, Steven, Farruggella, Thomas, DiStefano, Peter S., Curtis, Rory, Panayotatos, Nikos, Gascan, Hugues, Chevalier, Sylvie, Yancopoulos, George D.

“…The α component of the receptor for ciliary neurotrophic factor (CNTF) differs from other known growth factor receptors in that it is anchored to cell…”
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Angiopoietins 3 and 4: Diverging Gene Counterparts in Mice and Humans by Valenzuela, David M., Griffiths, Jennifer A., Rojas, Jose, Aldrich, Thomas H., Jones, Pamela F., Zhou, Hao, McClain, Joyce, Copeland, Neal G., Gilbert, Debra J., Jenkins, Nancy A., Huang, Tammy, Papadopoulos, Nick, Maisonpierre, Peter C., Davis, Samuel, Yancopoulos, George D.

“…The angiopoietins have recently joined the members of the vascular endothelial growth factor family as the only known growth factors largely specific for…”
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LIFRβ and gp 130 as heterodimerizing signal transducers of the tripartite CNTF receptor by DAVIS, S, ALDRICH, T. H, STAHL, N, LI PAN, TAGA, T, KISHIMOTO, T, IP, N. Y, YANCOPOULOS, G. D

“…The ciliary neurotrophic factor (CNTF) receptor complex is shown here to include the CNTF binding protein (CNTFR[Alpha]) as well as the components of the…”
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LIFRβ and gp130 as Heterodimerizing Signal Transducers of the Tripartite CNTF Receptor by Davis, Samuel, Aldrich, Thomas H., Stahl, Neil, Pan, Li, Taga, Tetsuya, Kishimoto, Tadamitsu, Ip, Nancy Y., Yancopoulos, George D.

“…The ciliary neurotrophic factor (CNTF) receptor complex is shown here to include the CNTF binding protein (CNTFRα) as well as the components of the leukemia…”
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The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development by Ip, Nancy Y, McClain, Joyce, Barrezueta, Nestor X, Aldrich, Thomas H, Pan, Li, Li, Yanping, Wiegand, Stanley J, Friedman, Beth, Davis, Samuel, Yancopoulos, George D

“…We recently proposed that ciliary neurotrophic factor (CNTF) shares two receptor components with a generally acting cytokine, leukemia inhibitory factor (LIF),…”
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Expression of normal and mutant ras proteins in human acute leukemia by Shen, W P, Aldrich, T H, Venta-Perez, G, Franza, Jr, B R, Furth, M E

“…The expression of normal and mutant ras genes in human acute leukemias was assessed by the direct analysis of p21ras polypeptides, using immunoprecipitation…”
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trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor by Squinto, Stephen P, Stitt, Trevor N, Aldrich, Thomas H, Davis, Samuel, Blanco, Stella M, RadzieJewski, Czeslaw, Glass, David J, Masiakowski, Piotr, Furth, Mark E, Valenzuela, David M, Distefano, Peter S, Yancopoulos, George D

“…A variety of findings seem to functionally link brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), while distinguishing both of these factors…”
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Abundant Expression of Ras Proteins in Aplysia Neurons by SWANSON, M. E, ELSTE, A. M, GREENBERG, S. M, SCHWARTZ, J. H, ALDRICH, T. H, FURTH, M. E

“…We have cloned a DNA fragment from the marine mollusc Aplysia californica, which contains sequences homologous to mammalian ras genes, by screening a genomic…”
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Expression of ras proto-oncogene proteins in normal human tissues by Furth, M E, Aldrich, T H, Cordon-Cardo, C

“…The expression of ras proto-oncogenes in normal human tissues was studied by immunohistochemical staining and by immunoblotting using monoclonal antibodies. We…”
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Neurotrophic factors, their receptors, and the signal transduction pathways they activate by Yancopoulos, G D, Maisonpierre, P C, Ip, N Y, Aldrich, T H, Belluscio, L, Boulton, T G, Cobb, M H, Squinto, S P, Furth, M E

“…Our studies of the spatiotemporal availability of neurotrophic factors, coupled with tagged ligand binding assays that identify cell bearing receptors for…”
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Biological effects of a murine retrovirus carrying an activated N-ras gene of human origin by Souyri, M, Koehne, C F, O'Donnell, P V, Aldrich, T H, Furth, M E, Fleissner, E

“…We have introduced a genomic DNA clone of a mutated human N-ras gene from a T-cell leukemia cell line into a retroviral vector equipped with a neo resistance…”
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Antisera to the variable region of ras oncogene proteins, and specific detection of H-ras expression in an experimental model of chemical carcinogenesis by Bizub, D, Heimer, E P, Felix, A, Chizzonite, R, Wood, A, Skalka, A M, Slater, D, Aldrich, T H, Furth, M E

“…Antisera were prepared in mice, rats and rabbits by immunization with peptides corresponding to regions of highest variability, located near the C-termini of…”
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Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning by Davis, Samuel, Aldrich, Thomas H, Jones, Pamela F, Acheson, Ann, Compton, Debra L, Jain, Vivek, Ryan, Terence E, Bruno, Joanne, Radziejewski, Czeslaw, Maisonpierre, Peter C, Yancopoulos, George D

“…TIE2 is a receptor-like tyrosine kinase expressed almost exclusively in endothelial cells and early hemopoietic cells and required for the normal development…”
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Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering by Davis, Samuel, Papadopoulos, Nick, Aldrich, Thomas H, Maisonpierre, Peter C, Huang, Tammy, Kovac, Lubomir, Xu, April, Leidich, Raymond, Radziejewska, Elzbieta, Rafique, Ashique, Goldberg, Judah, Jain, Vivek, Bailey, Kevin, Karow, Margaret, Fandl, Jim, Samuelsson, Steven J, Ioffe, Ella, Rudge, John S, Daly, Thomas J, Radziejewski, Czeslaw, Yancopoulos, George D

“…Angiopoietins are a recently discovered family of angiogenic factors that interact with the endothelial receptor tyrosine kinase Tie2, either as agonists…”
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Mollusca from the Upper Miocene of South Carolina with Descriptions of New Species by Julia A. Gardner, T. H. Aldrich

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The Grand Gulf Formation by Smith, Eugene A., Aldrich, Truman H.

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The Grand Gulf Formation by Smith, Eugene A., Aldrich, Truman H.

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