Search Results - "T. Caputo"
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Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels
Published in Cell (11-06-2010)“…Potassium channels embedded in cell membranes employ gates to regulate K + current. While a specific constriction in the permeation pathway has historically…”
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Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint
Published in Proceedings of the National Academy of Sciences - PNAS (08-08-2017)“…Glycoproteins traversing the eukaryotic secretory pathway begin life in the endoplasmic reticulum (ER), where their folding is surveyed by the 170-kDa…”
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Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins
Published in Scientific reports (04-03-2021)“…Puromycin and the Streptomyces alboniger -derived puromycin N -acetyltransferase (PAC) enzyme form a commonly used system for selecting stably transfected…”
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Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases--Not Glycolipid Processing Enzymes
Published in PLoS neglected tropical diseases (14-03-2016)“…It has long been thought that iminosugar antiviral activity is a function of inhibition of endoplasmic reticulum-resident α-glucosidases, and on this basis,…”
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Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4
Published in Antiviral research (01-05-2016)“…The antiviral activity of UV-4 was previously demonstrated against dengue virus serotype 2 (DENV2) in multiple mouse models. Herein, step-wise minimal…”
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Gold standard strategic plans: how well do Canadian police services do?
Published in Police practice & research (03-05-2020)“…This paper reports the results of a content analysis of the business/strategic plans of 23 Canadian police services that provide service to 48% of the…”
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Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint
Published in Frontiers in molecular biosciences (14-12-2022)“…None of the current data processing pipelines for X-ray crystallography fragment-based lead discovery (FBLD) consults all the information available when…”
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Lymphatic ascites following pelvic and paraaortic lymphadenectomy procedures for gynecologic malignancies
Published in Gynecologic oncology (01-04-2012)“…Abstract Objective Lymphatic ascites is an unusual complication in patients with cancer. In the gynecologic oncology patient population, the most common…”
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Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines
Published in Heliyon (01-06-2020)“…Regulation of type-I interferon (IFN) production is essential to the balance between antimicrobial defence and autoimmune disorders. The human protein-coding…”
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Electrical resistivity tomography imaging of the near-surface structure of the Solfatara crater, Campi Flegrei (Naples, Italy)
Published in Bulletin of volcanology (01-04-2015)“…We describe the results from an electrical resistivity tomography (ERT) survey performed inside the Solfatara crater, located in the central part of the Campi…”
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Symptoms of ovarian cancer
Published in Obstetrics and gynecology (New York. 1953) (01-08-2001)“…OBJECTIVE: To examine the symptoms of ovarian cancer in patients compared with symptoms experienced by healthy women using a case-control design. METHODS:…”
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Feasibility, safety and learning curve of robotic laparo-endoscopic single site gynecologic and gyneco-oncologic surgery
Published in Gynecologic oncology (01-10-2015)Get full text
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A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint
Published in iScience (20-10-2023)“…Misfolded glycoprotein recognition and endoplasmic reticulum (ER) retention are mediated by the ER glycoprotein folding quality control (ERQC) checkpoint…”
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Multi-parametric study of an eruptive phase comprising unrest, major explosions, crater failure, pyroclastic density currents and lava flows: Stromboli volcano, 1 December 2020–30 June 2021
Published in Frontiers in earth science (Lausanne) (22-08-2022)“…Open conduit volcanoes like Stromboli can display elusive changes in activity before major eruptive events. Starting on December 2020, Stromboli volcano…”
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Treatment With Adjuvant Pelvic Radiation Therapy ± Vaginal Brachytherapy in Patients With High-Risk Stage I or Stage II Uterine Papillary Serous, Clear Cell, and High-Grade Endometrioid Carcinoma
Published in International journal of radiation oncology, biology, physics (01-09-2014)Get full text
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234: MMP2 as a molecular biomarker of proficient tumor–stroma cross-talk in lung cancer
Published in European journal of cancer (1990) (01-07-2014)Get full text
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Risk-reducing salpingectomy at the time of benign hysterectomy and permanent sterilization: A survey of obstetricians/gynecologists
Published in Gynecologic oncology (01-07-2013)Get full text
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Molecular alterations of PIK3CA in uterine malignant mesodermal mixed tumors and clear cell carcinomas
Published in Gynecologic oncology (01-07-2013)Get full text
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